Possible Causes for large joint involvement Osteoarthritis RESULTS: A 43-year-old Caucasian woman of normal stature presented with a 24-year history of symmetrical polyarticular OA involving both large and small joints. [ncbi.nlm.nih.gov] These measures are particularly important when large, weight-bearing joints are involved, such as the hips or knees. [medicinenet.com] In fact, even modest weight reduction can help to decrease symptoms of osteoarthritis of the large joints, such as the knees and hips. [medicinenet.com] Hemochromatosis […] arthroplasty indications large joint involvement Orthopaedic Manifestations Bilateral ankle arthritis hemochromatosis should be suspected when symmetrical ankle arthropathy [orthobullets.com] large subchondral cysts, uniform loss of joint space and chondrocalcinosis. [cancertherapyadvisor.com] […] damage) phlebotomy regime indications weekly blood letting sessions to reduce serum ferritin levels contraindications severe anemia congestive heart failure Operative total joint [orthobullets.com] Pseudogout Patients with progressive large joint involvement such as the knee may benefit from joint replacement. [health24.com] Primarily affects the elderly Usually involves large joints Symptom onset is usually insidious. [unboundmedicine.com] self-limiting, synovitis) Chronic CPPD crystal inflammatory arthritis (1)[C] Chronic CPPD crystal deposition may cause a progressive degenerative arthritis in numerous joints [unboundmedicine.com] Relapsing Polychondritis large and small joints, with a predilection for the costochondral joints and knees. [msdmanuals.com] The arthritis is usually asymmetric and oligo- or polyarticular, and it involves both large and small peripheral joints. [what-when-how.com] Nasal cartilage inflammation is the next most common manifestation, followed by arthritis that varies from arthralgias to symmetric or asymmetric nondeforming arthritis involving [msdmanuals.com] Bacterial Arthritis These levels were lower in patients with small joint involvement than in those with large joint involvement. [medpagetoday.com] The proportion of patients with large joint involvement (hip and particularly knee) was significantly higher in the antibiotics dexamethasone group (92.3%) than in the antibiotics-only [pediatrics.aappublications.org] Late disease - is mainly involving joints, most commonly a single knee with intermittent, relatively painless large effusions lasting days or even weeks. [pmmonline.org] Pigmented Villonodular Synovitis PVNS generally affects large joints but occasionally involves the temporomandibular joint (TMJ), with occasional extension into the middle cranial fossa. [ncbi.nlm.nih.gov] This case described here is the first case of PVNS involving such a large numbers of joints that has been reported in the literature. [ncbi.nlm.nih.gov] The diffuse form typically involves the large joints (see the first 2 images below), while the localized form typically occurs around the small joints of the hands and feet [emedicine.com] Shoulder Osteoarthritis PURPOSE: The purpose of this study was to evaluate patients who underwent isolated arthroscopic debridement and capsular release without any other procedures for primary glenohumeral osteoarthritis to determine clinical and functional outcomes and time until conversion to shoulder arthroplasty. METHODS: We[…] [ncbi.nlm.nih.gov] Hemophilia Fetal Pediatr Pathol. 2015;34(4):248-51. doi: 10.3109/15513815.2015.1051250. Epub 2015 Jun 24. Author information 1 Clinic for Ginecology and Obstretics, Clinical Centre of Serbia, Department Neonatology, Belgrade, Serbia. Abstract Hemophilia is the most common inherited coagulation disorder, and approximately one-half of[…] [ncbi.nlm.nih.gov] Hemophilic Arthropathy joint involvement, total joint replacement remains the only effective treatment for end-stage disease. [appliedradiology.com] Large joints are most commonly involved in the following order of frequency 2 : knee elbow ankle hip shoulder Plain radiograph joint effusion is seen in the setting of hemarthrosis [radiopaedia.org] The joint involvement was established on a scale of 0 (no abnormalities), I (minimal amount of hemosiderin), II (large amount of hemosiderin and isolated cartilaginous erosion [ncbi.nlm.nih.gov] Calcific Tendinitis of the Shoulder OBJECTIVE: To define prognostic factors in chronically symptomatic patients with calcific tendinitis of the shoulder. METHODS: We evaluated 420 patients (488 shoulders) in the context of a prospective cohort study. Epidemiologic data were assessed. The radiographic and sonographic appearance of the calcific[…] [ncbi.nlm.nih.gov] Eosinophilic Fasciitis Eosinophilic fasciitis (), also known as "Shulman's syndrome", is a form of fasciitis, the inflammatory diseases that affect the fascia, the connective tissues surrounding muscles, blood vessels and nerves. Unlike other diseases in that category, it is limited to the arms and legs, and usually resolves itself, although[…] [en.wikipedia.org] Rheumatic Fever In ARF the large joints are involved while small joints are not. JIA can affect both large and small joints. [pmmonline.org] This is the most common manifestation of ARF, usually involves large joints, and is migratory in nature. It responds dramatically to high-dose salicylates. Carditis. [web.archive.org] - arthritis: the arthritis is typically symmetrical and involves large joints such as the knees, ankles, elbows, and wrists. [childrensheartinstitute.org] Behçet Disease Joints[edit] Arthritis is seen in up to half of people, and is usually a non-erosive poly or oligoarthritis primarily of the large joints of the lower extremities.[4] Brain [en.wikipedia.org] [edit] CNS involvement most often occurs as a chronic meningoencephalitis. [en.wikipedia.org] […] causing severe vascular collapse and death from bleeding in the lungs.[4] Nodules, consolidations, cavities and ground glass lesions are common in patients with pulmonary involvement [en.wikipedia.org] Traumatic Arthropathy The arthropathy principally involves large joints such as elbows, hips, knees, and ankles. [diki.pl] Primary synovial (osteo)chondromatosis typically involves large joints. [jaocr.org] Arthropathy with stiff joints, diabetes, or fatigue, may be the presenting complaint. Spondylarthropathy is any form of arthropathy of the vertebral column. [diki.pl] Serum Sickness Arthritis or arthralgias (10-50%) usually affect multiple large joints, but occasionally, small joints and joints of spine and temporomandibular joint may be inflamed. [whale.to] Lymphadenopathy (10-20%) may be generalized or may involve tenderness in the nodes that drain the injection site; splenomegaly may occur. [whale.to] Intermittent Hydrarthrosis Other joints may also be involved along with the knee. Effusions are large, restricting range of motion but significant pain is not a feature. [en.wikipedia.org] Signs and symptoms [ edit ] Repeated, periodic joint effusions of the knee. Usually one knee is affected but sometimes both knees. [en.wikipedia.org] Tenderness of the joint may or may not be present. [1] Aspirated synovial fluid is usually sterile [2] but will sometimes show elevated cell count ( 100 cells/mL) with 50% [en.wikipedia.org] Ochronosis with Alkaptonuria For large joints, involvement of the joint spaces was scored as absent (0); minimal, with osteophytes, subchondral cysts, or both, but no narrowing of joint spaces (1); mild [nejm.org] Clinically, alkaptonuria resembles ankylosing spondylitis 27 in its particular damage to the spine and large joints but differs in sparing the sacroiliac joint. [nejm.org] The spinal involvement results in kyphosis, height loss, and decreased lumbar flexion, and the joint disease decreases the range of motion and causes effusions. [nejm.org] Ross River Fever Ross River fever is a debilitating viral illness spread by mosquitoes that can leave you bedridden for weeks, sometimes longer. [Image source: iStockphoto ] Ross River fever is caused by a viral infection, transmitted through mosquito bites. The Ross River virus was named after the river in northern Queensland[…] [abc.net.au] Insect Bite or the area from one large joint to another, such as from the ankle to the knee? [cigna.com] Yes Rapid swelling of lips, tongue, mouth, or throat No Rapid swelling of lips, tongue, mouth, or throat Does swelling involve the palms of the hands, the soles of the feet [cigna.com] Cystitis Over time, involvement of large joints and the spine causes significant joint contractures, gait disturbance, and scoliosis and/or kyphosis, resulting in abnormal posture [ncbi.nlm.nih.gov] Onset – typically between ages three and six years – begins with the involvement of the interphalangeal joints. [ncbi.nlm.nih.gov] Congenital Abnormality Progressive pseudorheumatoid dysplasia (PPD) is a skeletal dysplasia characterized by predominant involvement of articular cartilage with progressive joint [ncbi.nlm.nih.gov] Arthritis 0: large joint 1: 2-10 large joints 2: 1-3 small joints (with or without involvement of large joints) 3: 4-10 small joints (with or without involvement of large joints) 5 [radiopaedia.org] It may involve 5 or more large and small joints of the legs and arms, as well as the jaw and neck. [medlineplus.gov] joint gives 0 points Involvement of 2–10 large joints gives 1 point Involvement of 1–3 small joints (with or without involvement of large joints) gives 2 points Involvement [en.wikipedia.org] Hypertension Dynamic (isotonic) refers to the regular, purposeful movement of joints and large muscle groups compared with isometric exercise, which involves static contraction of muscles [doi.org] […] and large muscle groups. [doi.org] […] without joint movement. [doi.org] Arthritis due to Ulcerative Colitis The common pattern of joint involvement was asymmetric arthritis in the lower extremities large joints. The most common type of arthritis was inflammatory. [cjhr.org] The common pattern of joint involvement was asymmetric arthritis in in the lower extrimities large joints. The most common type of arthritis was inflammatory. [jmedsoc.org] It usually involves a few large joints at a time, most frequently a knee or ankle but sometimes a wrist. The joints are active when the colon is active. [hopkinsarthritis.org] Ganglion Cyst Initially treatment involves rest, bracing, activity modification and over the counter pain medication. [thecenteroregon.com] Large cysts can cause concern about appearance Diagnosis and treatment Ganglion cysts often don’t require surgery and may disappear or reduce in size with time. [thecenteroregon.com] […] the wrist Cysts on the finger joint are often associated with arthritis Symptoms Visible lump, although some cysts remain hidden under the skin Pain due to pressure on the joint [thecenteroregon.com] Hyperuricemia In cases where one or two accessible joints are involved, intra-articular injection of corticosteroid (in large joints: 10 to 40 mg of triamcinolone hexacetonide [Aristospan [aafp.org] Gout can affect any joint in your body, but flares often first appear in your large toe. Feet, ankles, knees, and elbows are also common sites of gout. [healthline.com] Gouty tophi involving the proximal interphalangeal joint with erythema of the overlying skin. [aafp.org] Streptococcal Infection ARF can present with migratory arthritis involving primarily the large joints, carditis and valvulitis, central nervous system involvement, rash, or any combination of these [casesjournal.biomedcentral.com] joints, subcutaneous nodules, erythema marginatum, and sydenham chorea (involuntary, purposeless movement). [en.wikipedia.org] The most common clinical finding is a migratory arthritis involving multiple joints. [26] Other indicators of GAS infection such as a DNAase or ASO serology test must confirm [en.wikipedia.org] Fibroma However, FTS rarely arises around a large joint (knee, shoulder, elbow, and ankle) with intra-articular or extra-articular involvement. [ncbi.nlm.nih.gov] Of the FTSs occurring around large joints, the most frequently involved joint was the knee. [bmcmusculoskeletdisord.biomedcentral.com] The knee joint is the most commonly involved joint for FTSs around large joints [2, 6–27]. [ncbi.nlm.nih.gov] Juvenile Seronegative Polyarthritis involved large joint involvement (knees, ankles) asymmetric findings (leg length discrepancy, involved limb ends up LONGER) M:F 1:4, age 2-3y most common type early-onset [orthobullets.com] Types Pauciarticular (4 or fewer joints involved) Age at presentation Involves large joints and is typically asymmetric Boys may develop Sacroiliitis Iridocyclitis may be [fpnotebook.com] It can be symmetrical with large and small joints involved with swelling. It can present with stiffness but minimal swelling. This is often a destructive arthritis. [patient.info] Fracture […] articular involvement and fracture-dislocations impression fracture shear (longitudinal split) fracture combined fracture: T-shape, Y-shape, multifragmentary Features to [radiopaedia.org] joints of a long bone must be assessed) impaction - usually refers to a stable and typically simple fracture in which the fragments are driven into each other Fractures with [radiopaedia.org] […] dislocation of more than the shaft diameter cum distractione: a gap between the fracture ends prevents healing ad peripheriam: rotational displacement (the position of both large [radiopaedia.org] Juvenile Idiopathic Arthritis involved large joint involvement (knees, ankles) asymmetric findings (leg length discrepancy, involved limb ends up LONGER) M:F 1:4, age 2-3y most common type early-onset [orthobullets.com] Most young children do not complain of stiffness or pain, but there may be changes in gait or function. 2 Any joint may be affected, but large joints are involved more frequently [web.archive.org] Large as well as small joints are symmetrically involved and there is even involvement of the jaw and neck. [symptoma.com]
