Possible Causes for Large Joint Involvement in USA

  • Bacterial Arthritis
    Large Joint Involvement Joint Deformity

    Bacterial arthritis is predominantly caused by Staphylococcus aureus, streptococci, and Neisseria gonorrhoeae. Joint pain and swelling (involving either one or more joints), as well as fever, are three cardinal symptoms seen in these patients. The diagnosis can be made after a proper physical examination, while the…[1]

  • Relapsing Polychondritis
    Large Joint Involvement

    Relapsing polychondritis is a rare inflammatory disease characterized by recurrent inflammation of cartilage and other structures rich in proteoglycans, and involves damage to eye, ear, nose and cardiovascular system. Typically, relapsing polychondritis presents with sudden pain and common signs of inflammation at…[2]

  • Rheumatic Fever
    Large Joint Involvement

    Rheumatic fever is a systemic inflammatory disease that may develop as a delayed reaction to an infection with group A beta-hemolytic streptococci. It is most often seen in children and young adults. Rheumatic fever does not present with specific signs and symptoms. There is sudden onset of fever, joint pain,…[3]

  • Hemophilic Arthropathy
    Large Joint Involvement Joint Deformity
  • Serum Sickness
    Large Joint Involvement

    When first exposed to drugs containing proteins of other species, individuals showcase the signs and symptoms after about 7 – 10 days. When exposed for the second time, the symptoms appear pretty fast within 1 – 4 days. The signs and symptoms of serum sickness include the following: Fever accompanied by body…[4]

  • Ross River Fever
    Large Joint Involvement

    Ross river fever is caused by an arbovirus infection following mosquito bites. The most prominent clinical features are arthralgia, rashes, myalgia and fever, which respond favorably to nonsteroidal anti-inflammatory agents. The virus is native to Australia and its main reservoir hosts are marsupials. Ross river fever…[5]

  • Ochronosis with Alkaptonuria
    Large Joint Involvement
  • Shoulder Osteoarthritis
    Large Joint Involvement
  • Pigmented Villonodular Synovitis
    Large Joint Involvement

    Pigmented villonodular synovitis is an inflammatory disease of unknown etiology. Local invasive growth of the synovial layer lining joints, tendons and bursae causes pain and functional impairment of the affected structure. Insidious symptom onset and unspecific complaints are the main cause of delays in PVNS…[6]

  • Behçet Disease
    Large Joint Involvement

    Behcet’s syndrome or Behcet’s disease is a multisystem inflammatory disease characterized by oral aphthous ulcers and a myriad potential systemic manifestations. Behcet’s syndrome is confirmed in the presence of any two of the following criteria: Recurrent genital ulcers Anterior or posterior uveitis or retinal…[7]

Further symptoms

Similar symptoms


  1. Bacterial Arthritis, Symptoma
  2. Relapsing Polychondritis, Symptoma
  3. Rheumatic Fever, Symptoma
  4. Serum Sickness, Symptoma
  5. Ross River Fever, Symptoma
  6. Pigmented Villonodular Synovitis, Symptoma
  7. Behçet Disease, Symptoma