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13 Possible Causes for Large Joint Involvement, Proximal Interphalangeal Joint Space Narrowed

  • Osteoarthritis

    Hand X-rays showed joint space narrowing, osteophytosis and bone sclerosis of the proximal interphalangeal (PIP) joints.[ncbi.nlm.nih.gov] RESULTS: A 43-year-old Caucasian woman of normal stature presented with a 24-year history of symmetrical polyarticular OA involving both large and small joints.[ncbi.nlm.nih.gov] A joint effusion is the presence of increased intra-articular fluid. [1] It may affect any joint. Commonly it involves the knee.[en.wikipedia.org]

  • Hemochromatosis

    Involvement of proximal interphalangeal joints, radiographic joint space narrowing and cartilage destruction is often evident in hemochromatosis.[clinicaladvisor.com] […] arthroplasty indications large joint involvement Orthopaedic Manifestations Bilateral ankle arthritis hemochromatosis should be suspected when symmetrical ankle arthropathy[orthobullets.com] ), large subchondral cysts, uniform loss of joint space and chondrocalcinosis.[cancertherapyadvisor.com]

  • Arthritis

    Abbreviations DAS: Disease Activity Score DMARD: disease-modifying antirheumatic drugs JSN: joint space narrowing MRI: magnetic resonance imaging PIP: proximal interphalangeal[doi.org] 0: large joint 1: 2-10 large joints 2: 1-3 small joints (with or without involvement of large joints) 3: 4-10 small joints (with or without involvement of large joints) 5[radiopaedia.org] It may involve 5 or more large and small joints of the legs and arms, as well as the jaw and neck.[medlineplus.gov]

  • Juvenile Psoriatic Arthritis

    Joints mostly involved are distal interphalangeal, proximal interphalangeal, metatarsophalangeal, and metacarpophalangeal joints.[boneandspine.com] involvement: asymmetric oligoarthritis affecting large and small joints, with or without dactylitis, chronic uveitis, and antinuclear antibodies.[ncbi.nlm.nih.gov] Clinical findings Joint involvement a) Large joints The most commonly involved large joints at both presentation and during the course of the disease were the knee (67%) and[ped-rheum.biomedcentral.com]

  • Rheumatoid Arthritis

    Abbreviations DAS: Disease Activity Score DMARD: disease-modifying antirheumatic drugs JSN: joint space narrowing MRI: magnetic resonance imaging PIP: proximal interphalangeal[doi.org] 0: large joint 1: 2-10 large joints 2: 1-3 small joints (with or without involvement of large joints) 3: 4-10 small joints (with or without involvement of large joints) 5[radiopaedia.org] […] gives 0 points Involvement of 2–10 large joints gives 1 point Involvement of 1–3 small joints (with or without involvement of large joints) gives 2 points Involvement of[en.wikipedia.org]

  • Arthropathy

    Joints frequently involved in chronic arthritis are ankles, knees, hands, wrist, and metacarpophalangeal and proximal interphalangeal joints, rarely, the sacroiliac and temporomandibular[medcraveonline.com] Large joints in a symmetrical pattern were more often involved than small joints.[acrabstracts.org] Abbreviations DAS: Disease Activity Score DMARD: disease-modifying antirheumatic drugs JSN: joint space narrowing MRI: magnetic resonance imaging PIP: proximal interphalangeal[doi.org]

  • Erosive Osteoarthrosis

    The dominant features are those of osteoarthritis, particularly in terms of distribution: distal interphalangeal (DIP) joints proximal interphalangeal (PIP) joints first carpometacarpal[radiopaedia.org] Large joints are also involved eventually.[icliniq.com] The patient also has involvement of the proximal interphalangeal joints (PIP) of the index, middle and ring fingers (Bouchard’s nodes). Figure 2.[intechopen.com]

  • Enthesitis-Related Arthritis

    Long-term sequelae of polyarticular disease includes periarticular osteopenia, generalized increase in the size of epiphyses, accelerated bone age, narrowed joint spaces ([emedicine.medscape.com] In comparison with the scientific picture seen in adults, the primary symptoms in the paediatric condition involve largely the peripheral bones with asymmetric oligoarticular[enthesitis.org] This form of juvenile idiopathic arthritis affects about 50 percent of children with JIA, and involves four or fewer joints.[chop.edu]

  • Progressive Pseudorheumatoid Dysplasia

    Figure 2 Bony enlargement of metacarpophalangeal andproximal interphalangeal joints Figure 3 X-ray of the hands revealing swelling of themetacarpophalangeal and proximal[docslide.net] The joint enlargement, stiffness, and restricted range of movement gradually involve all large joints (i.e., knees, hips, wrists, and elbows) [ Dalal et al 2012, Garcia Segarra[ncbi.nlm.nih.gov] Plain radiographs of the hands showed bony enlargement of metacarpophalangeal, proximal interphalangeal joints and joint narrowing.Theknee jointswereenlarged similarly.Radiographs[docslide.net]

  • Spondyloepiphyseal Dysplasia - Spondyloepimetaphyseal Dysplasia

    X-ray of the hands showed periarticular osteoporosis, significant narrowing of the joint spaces of proximal interphalengial and distal interphalangeal joints and osseous enlargement[clinmedjournals.org] The epiphysis are small and precocious osteoarthropathy was observed involving small and large joints.[ncbi.nlm.nih.gov] X-ray of the hands showed periarticular osteoporosis, significant narrowing of the joint spaces of PIP and distal interphalangeal (DIP) joints and osseous enlargement of the[clinmedjournals.org]

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