Possible Causes for Large Penis Wiedemann-Rautenstrauch Syndrome penis Growth Postnatal growth deficiency Hearing Sensorineural hearing loss Intrauterine development Intrauterine growth retardation Joints and Tendons Joint contractures [datagenno.com] […] hands and feet with long fingers and toes + + + + + + + NR + + + + - Prepucial hypoplasia NR NR NR - + + - Large penis + + NR - - - - Cryptorchidism NR NR + - + + + Gynaecomastia [cureus.com] Cardiovascular Cardiovascular abnormalities Ventricular dilatation with cortical atrophy Endocrine and/or Exocrine Hyperprolactinemia Hypothyroidism Genitourinary Hypoplastic prepuce Large [datagenno.com] Donohue Syndrome Affected females may have cystic ovaries and an abnormally enlarged clitoris/ breasts, while males may be afflicted with an abnormally large penis. [symptoma.com] Figure 4: Thin and emaciated extremity with protuberant abdomen and large penis Click here to view Leprechaunism was first described by Donohue (1948) [3] and since then it [e-ijd.org] Enlarged penis 0000040 Low-set, posteriorly rotated ears 0000368 Macrotia Large ears 0000400 Proptosis Bulging eye Eyeballs bulging out Prominent eyes Prominent globes Protruding [rarediseases.info.nih.gov] Bannayan-Riley-Ruvalcaba Syndrome […] bowel loops 4 pigmented macules on the glans of the penis (speckled penis) Musculoskeletal manifestations: hypotonia scoliosis pectus excavatum joint hyperextensibility Women [radiopaedia.org] […] head size (macrocephaly), pigmented spots (maculae) on the penis and benign tumors and tumor-like growths in the intestine called hamartomas. [rarediseases.org] […] features include: macrocephaly lipomatosis dermal and deep visceral lipomas angiolipomas hemangiomata hamartomatous intestinal polyps most commonly in terminal ileum and in large [radiopaedia.org] Roberts Syndrome Enlarged penis (relatively large appearance in relation to the reduced limbs), hypospadias, cryptorchidism, hypogonadism [1, 3,14,17,23]. Female genitalia. [thefetus.net] Congenital Adrenal Hyperplasia due to 11-Beta-Hydroxylase Deficiency 1. Stokowski L. Congenital adrenal hyperplasia: an endocrine disorder with neonatal onset. Crit Care Nurs Clin North Am. 2009;21:195–212. 2. New M, Ghizzoni L, Lin-Su K. An update of congenital adrenal hyperplasia. En: Lifshitz F, editor. Pediatric endocronology. New York: Informa Healthcare; 2007. p. 227–45. 3.[…] [revistas.fucsalud.edu.co] X-linked Mental Retardation Type Cabezas [ more ] 0000303 Micropenis Short penis Small penis [ more ] 0000054 Mood swings 0000720 Relative macrocephaly Relatively large head 0004482 Striae distensae Stretch marks [rarediseases.info.nih.gov] […] tongue [ more ] 0000158 Mandibular prognathia Big lower jaw Increased projection of lower jaw Increased size of lower jaw Large lower jaw Prominent chin Prominent lower jaw [rarediseases.info.nih.gov] […] more ] 0001249 Joint laxity Joint instability Lax joints Loose-jointedness Loosejointedness [ more ] 0001388 Macroglossia Abnormally large tongue Increased size of tongue Large [rarediseases.info.nih.gov] Cowper Gland Carcinoma As the penis fills with blood, it becomes rigid and erect, which allows for penetration during sex. [my.clevelandclinic.org] The body or shaft: Shaped like a tube or cylinder, the body of the penis is made up of three internal chambers. [my.clevelandclinic.org] Inside these chambers there’s a special, sponge-like erectile tissue that contains thousands of large spaces that fill with blood when you’re sexually aroused. [my.clevelandclinic.org] Penile Hematoma Hematoma of prepuce Hemorrhage of corpus cavernosum Hemorrhage of penis Hypertrophy of corpus cavernosum Hypertrophy of penis Irritation of penis Large penis Lichen planus [icdlist.com] Large Penile Hematoma [gpvec.unl.edu] This can cause the penis to have a large bump or irregularity on the shaft. There can also be a great deal of pain associated with the hematoma. [healthcentral.com] Diphallia The small, immature and nonfunctional penis protruded on one side of the large, normal penis. The secondary penis had glans but without urinary meatus. [en.wikipedia.org] Fibular Dimelia-Diplopodia Syndrome […] anomalies Corpus cavernosum sclerosis Hypospadias/epispadias/bent penis Macropenis/megapenis/large penis Micropenis/small penis/agenesis Penis duplication/diphallia/penoscrotal [readbag.com] […] dysgenesis True hermaphrodism Clitoris/labia majora/labia minora/female external genitalia hypoplasia Male internal genitalia anomaly/deferent ducts agenesis/ectopy/duplication Penis [readbag.com] Congenital Absence of the Penis An abnormally large penis frequently is present in males with precocious puberty, dwarfism, an overactive pituitary, or adrenal tumours. [britannica.com] Examples Ambiguous genitalia - a large clitoris or small penis. Cryptorchidism - absence of one or both testes from the scrotum. This includes undescended testes. [ipfs.io] Secondary buried penis may be the result of an overzealous circumcision with subsequent cicatricial scar (trapped penis), a large hernia, or a hydrocele. [omicsonline.org] Penile Carcinoma Among these variants is the exceedingly uncommon adenosquamous carcinoma (ASC), representing 1%-2% of all SCC of the penis. [ncbi.nlm.nih.gov] Large fungating squamous cell carcinoma of the penis Deirdre Mary Fanning, James Forde, Kevin O’Connor, Ted Mc Dermott Urology Department, St James’s Hospital, Dublin, Ireland [casereports.bmj.com] Prognosis of Cancer of the Penis (Squamous Cell Carcinoma of the Penis) Prognosis depends largely on the level of metastases and invasion. [myvmc.com] X-Linked Hypogonadotropic Hypogonadism without Anosmia […] and testes, as well as secondary sex characteristics, is largely normal. [symptoma.com] […] nXHH is associated with loss of libido, erectile dysfunctions, infertility, low muscle mass, a high percentage of body fat, and reduced well-being, but the development of penis [symptoma.com] Diencephalic Syndrome I have a condition called Diencephalic syndrome, meaning I have an extremely large penis. [dearcupid.org] I have also heard that men with large penis's do have to be careful when substataining an erection as it uses a lot of blood to make it erect, which can cause alot further [dearcupid.org] A female reader, anonymous, writes (20 June 2007): It actually says right here on this website that a large penis is a clinical symptom of the disorder. http://www.orpha.net [dearcupid.org] Calcinosis Cutis Metastatica Here, we describe a patient who presented with advanced metastatic calcinosis cutis with multiple lesions of the large joints, neck, hands, and penis. [ncbi.nlm.nih.gov] Calcinosis cutis is an unusual disorder characterized by large calcium phosphate deposition into cutaneous and subcutaneous tissues. [ncbi.nlm.nih.gov] Here, we discuss the case of a 26-year-old man presenting with unusually advanced skin and joint calcification of the shoulders, neck, hand, and penis. [ncbi.nlm.nih.gov] Buschke-Lowenstein Tumor It is a slow growing tumor, but if not treated, can grow to a large size and ulcerate the penis; if it involves the perianal region, it can cause bleeding and abscesses. [symptoma.com] […] most commonly occurs near the penis or anus. [rarediseases.org] It becomes a large cauliflower-like, hyperkeratotic, verrucous mass that is… (More) National Institutes of Health [semanticscholar.org] Agenesis of Uterus However, men’s penises are different sizes and a man who has a large penis may cause you some discomfort as he would any woman. [mrkh.org.uk] Congenital Generalized Lipodystrophy Type 1 Upon further assessment, he had acromegaloid features with loss of fat deposition over whole body with prominent muscle bulk, protruding tongue, large penis and phlebomegaly [hkjpaed.org] Adults may have large hands and feet and a strong, square jawbone if their hormone balance is off and they've kept growing. [webmd.com] They could have larger than usual sex organs (clitoris and ovaries, penis and testicles). A woman might have irregular periods or none at all. [webmd.com] Scrotal Elephantiasis B The penis is submerged within the scrotum. C The penis is partially submerged due to large bilateral hydroceles. [isradiology.org] Damage to the scrotum closed observed with the injuries, sdavljenia, accompanied by pain, hematoma (the latter sometimes reach large sizes, moving to the penis, perineum and [medicalency.com] After excising the large redundant, edematous scrotum, the penis was found and was dissected out with a circumcising incision around the corona and down to the base. [thefreelibrary.com] Agenesis or Aplasia of Uterine Body However, men’s penises are different sizes and a man who has a large penis may cause you some discomfort as he would any woman. [mrkh.org.uk] Priapism In this case, there is a large amount of blood flowing into the penis. Priapism constitutes a true urologic emergency. [medindia.net] The injury causes the artery within the erectile body to rupture, and thus pump large amount of blood to the penis continuously. [ucsfhealth.org] Among mechanical causes of priapism are obstructions such as large blood clots or tumours in the penis. [britannica.com] Penile Torsion Irritation of penis Large penis Lesion of penis Lesion penis Lichen planus of glans penis Lichen planus of penis Mass of penis Mass of prepuce Nocturnal erection of penis [icd9data.com] Lymphatics and Nerve Supply Lymphatic drainage from the glans penis drains into large trunks in the area of the frenulum. [emedicine.medscape.com] Degloving of penis, release of soft tissue causing torsion and resuturing of skin in reverse rotated position corrects the torsion to a large extent. [ijps.org] Impotence The data from this monitor is then assessed to analyse how often erections occurred, how long they lasted, and how rigid and large the penis was during the erections. [healthengine.com.au] Uterine Cervical Aplasia and Agenesis However, men’s penises are different sizes and a man who has a large penis may cause you some discomfort as he would any woman. [mrkh.org.uk] Peyronie Disease When the plaque is large enough, it causes painful curvature of the penis that may prevent intercourse. [med.unc.edu] It is worth noting that a large number of males who experience a penis injury do not go on to develop Peyronie's disease. [medicalnewstoday.com] When a man gets an erection, large amounts of blood flow into the erectile tissue, filling the blood channels which increases the penile size and gives the penis its rigidity [birminghamprostateclinic.co.uk] Rudiger's Syndrome The male had a small penis and large inguinal hernias. Both had bilateral simian creases. A high axial triradius and simple arches on all digits were found. [omim.org] Sarcoma of the Penis Several large studies have dmonstrated that smoking is associated with an increased incidence of squamous cell carcinoma of the penis. [health.am] Removing part or all of the penis If the cancer is large, or affecting too much of the penis, your surgeon may advise you to have part, or occasionally all, of the penis removed [macmillan.org.uk] If it has penetrated the deeper penile tissues or is large, surgery is the preferred treatment for most men. Radiation is an option but results are less certain. [healthcentral.com] Erythroplasia of Queyrat These tumors do not metastasize, but may destroy the glans and prepuce, and become so large that a partial penis amputation is necessary. [oncolex.org] Several large studies have dmonstrated that smoking is associated with an increased incidence of squamous cell carcinoma of the penis. [health.am] cancer of the penis is epidemiologically uncommon in our parts but when they do come, they so late and reluctant to cooperate till even later. [bmj.com] Redundant Prepuce Chapter First Online: 11 February 2017 Abstract Extensively large redundant part of the prepuce extended beyond the glans penis, sometimes representing more than three-quarters [link.springer.com] Because in the past the point of view, because the foreskin is too long can lead to a large number of production of smegma, and can cause cancer of the penis; and easily repeated [bestchinanews.com] […] may occur. 7 is likely to affect women's health Since a large quantity of smegma within the bacteria can invade the woman during intercourse caused by vaginal infections [tcmwell.com] Traumatic Urinary Bladder Rupture The penis rapidly loses its rigidity and a large bruise develops from the base of the penis to the head of the penis. A moderate amount of pain is associated with this. [healthcare.utah.edu] • When the Inf. fascia of UD is ruptured, urine can infiltrate the thigh or penis. 05-Jul-12 management of bladder injuries 22 23. PATHOPHYSIOLOGY... [slideshare.net] Usually patients have a lot of bleeding from the penis and a large bruise forms in the groin and perineum (the area between the anus and the scrotum). [healthcare.utah.edu]
