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837 Possible Causes for Large Platelets

  • Syndromic Diarrhea

    […] volume IEA IEA rare OMIM-CS:HEMATOLOGY LARGE PLATELETS (IN SOME PATIENTS) OMIM:222470 HPO:skoehler 18.11.2012 OMIM:222470 #222470 TRICHOHEPATOENTERIC SYNDROME 1; THES1;;THE[sourceforge.net] OMIM:222470 #222470 TRICHOHEPATOENTERIC SYNDROME 1; THES1;;THE SYNDROME;;DIARRHEA, SYNDROMIC;;DIARRHEA, FATAL INFANTILE, WITH TRICHORRHEXIS NODOSA HP:0011877 Increased mean platelet[sourceforge.net]

  • Bernard-Soulier Syndrome

    In fact, some authors recommend manual counting of these large platelets, as they are often mistaken as lymphocytes by automatic counters.[symptoma.com] Abstract Bernard-Soulier syndrome is an autosomal recessive coagulopathy characterized by thrombocytopenia, prolonged bleeding time and large platelets.[ncbi.nlm.nih.gov] platelets and failure of platelet aggregation with ristocetin.[ncbi.nlm.nih.gov]

  • Gray Platelet Syndrome

    Gray platelet syndrome (GPS) is a predominantly recessive platelet disorder that is characterized by mild thrombocytopenia with large platelets and a paucity of α-granules[ncbi.nlm.nih.gov] Gray platelet syndrome (GPS) is an autosomal recessive bleeding disorder that is characterized by large platelets that lack α-granules.[ncbi.nlm.nih.gov] Gray platelet syndrome (GPS) is a disorder characterized by thrombocytopenia and large platelets that lack alpha granules and their contents.[ncbi.nlm.nih.gov]

  • May-Hegglin Thrombocytopenia

    The actual platelet count was underestimated by the automated counter because of the abnormally large platelets.[bloodjournal.org] Peripheral blood film showed thrombocytopenia with large platelets and Döhle-like body neutrophil inclusions. Bone marrow examination was declined by the patient.[ghrnet.org] This case emphasizes the importance of the history and a review of the peripheral smear when abnormally large platelets give false readings on automated cell counters.[bloodjournal.org]

  • May-Hegglin Anomaly

    It is characterized by the presence of large platelets, leukocyte inclusions, and thrombocytopenia.[ncbi.nlm.nih.gov] Moreover, in all patients the subpopulation of large platelets had defective expression of this complex.[ncbi.nlm.nih.gov] […] the triad of thrombocytopenia, large platelets and characteristic leukocyte inclusions ('Döhle-like' bodies).[ncbi.nlm.nih.gov]

  • Autosomal Dominant Macrothrombocytopenia

    Platelet anisocytosis, increased percentage of large platelets and absence of leukocyte inclusions were observed in 26/30 (87%) of the examined blood smears.[onlinelibrary.wiley.com] […] disorders, may show large platelets, thrombocytopenia and neutrophilic inclusions on peripheral blood smear examination.[ijdvl.com] This syndrome is characterized by congenital thrombocytopenia associated with the presence of large platelets.[ncbi.nlm.nih.gov]

  • Inherited Platelet Disorder

    This syndrome is characterized by variable thrombocytopenia and large defective platelets.[ncbi.nlm.nih.gov] Giant platelet disorders are rare disorders featuring abnormally large platelets, thrombocytopenia and a tendency to bleeding.[en.wikipedia.org] It impairs platelet adhesion via a defect in the glycoprotein Ib/IX complex that binds endothelial VWF. Bleeding may be severe. Platelets are unusually large.[merckmanuals.com]

  • Severe Autosomal Recessive Macrothrombocytopenia

    Giant platelet disorders are rare disorders featuring abnormally large platelets, thrombocytopenia and a tendency to bleeding.[en.wikipedia.org] Design and Methods: We describe two Italian families with moderate thrombocytopenia with large platelets, defective platelet function and moderate/severe mucocutaneous bleeding[moh-it.pure.elsevier.com] […] count with very large platelets (macrothrombocytopenia).[ojrd.biomedcentral.com]

  • Von Willebrand Disease Type 2B

    This phenomenon induces the clearance of both large multimers and platelets, usually resulting in thrombocytopenia with slightly increased platelet size.[ncbi.nlm.nih.gov] Type 2B von Willebrand's disease (VWD) is an inherited bleeding disorder characterized by spontaneous binding of large von Willebrand factor (VWF) multimers to platelets in[moh-it.pure.elsevier.com] The mutant VWF aggregates more readily with platelets, resulting in the loss of large VWF multimers from circulation and thrombocytopenia secondary to platelet sequestration[bloodjournal.org]

  • Mediterranean Macrothrombocytopenia

    platelets.[discovery.ucl.ac.uk] Giant platelet disorders are rare disorders featuring abnormally large platelets, thrombocytopenia and a tendency to bleeding.[en.wikipedia.org] . - Platelets in Cavaliers: Too Few (Thrombocytopenia) and Too Large ( Macrothrombocytopenia )". CavalierHealth.org. Retrieved 14 November 2009.[wordaz.com]

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