Late Systolic Murmur: Causes & Reasons

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Possible Causes for Late Systolic Murmur

Mitral Valve Prolapse

On auscultation there may be a mid-systolic click and late systolic murmur. Reference: Criley et al. (1966). [gpnotebook.co.uk]

Late systolic murmurs and non-ejection (“mid-late”) systolic clicks. An analysis of 90 patients. Br Heart J. 1968;30:203–18. 17. [aafp.org]

The principal physical finding is a midsystolic click, which frequently is followed by a late systolic murmur. [aafp.org]

Mitral Valve Disease

The syndrome of mid-systolic click accompanying a systolic murmur was first described in the late 1800s, but it was in the early 1960s that its association with mitral regurgitation [mitralvalverepair.org]

Mid-systolic clicks. S Afr Med J1961;35:353–5. ↵ Ronan J, Perloff J. Systolic clicks and the late systolic murmur. [heart.bmj.com]

Physical examination most often reveals the presence of a mid-systolic click and a mid to late systolic murmur, which reflects the timing of prolapse in the setting of excess [mitralvalverepair.org]

Mitral Valve Insufficiency

[…] in isolated MR, did not differ significantly between pan-systolic and late-systolic murmur groups. [ncbi.nlm.nih.gov]

[…] may be the only distinctive signs.[4] Patients with mitral valve prolapse may have a holosystolic murmur or often a mid-to-late systolic click and a late systolic murmur. [en.wikipedia.org]

The midsystolic click and late systolic murmur are very position- and heart volume - dependent, so they are possible to miss if the person is only examined when lying face [emedicinehealth.com]

Papillary Muscle Dysfunction

Left ventricular S4 Late systolic or pansystolic murmur with late systolic accentuation What are the murmurs in papillary muscle dysfunction ? [notes.medicosnotes.com]

Abstract Nine girls are presented with variable late systolic murmurs (usually best heard sitting up); five of the nine had mid systolic clicks, minimal to mild mitral regurgitation [pediatrics.aappublications.org]

Occasionally, only a late systolic murmur is found indicating that the papillary muscle functions in early systole but later demonstrates its ischemia-induced functional impairment [link.springer.com]

Chordae Tendinae Rupture

systolic murmur that is best heard at the mitral region and may radiate to the axilla. [amboss.com]

MVP with MR causes a click with a late-systolic MR murmur. [merckmanuals.com]

Overview In most cases MVP is completely asymptomatic and is discovered incidentally due to auscultation of a characteristic "Mid-systolic Click" followed by a late systolic [pathwaymedicine.org]

Papillary Muscle Disorder

Functional papillary muscle insufficiency is characterized by an apical late systolic murmur and typically resolves without treatment. [msdmanuals.com]

Familial Mitral Valve Prolapse

Denny: The significance of late systolic murmurs. American Heart Journal, St. Louis, 1963, 66: 443. J. B. Barlow, C. K. Bosman, J. W. C. [whonamedit.com]

[…] and a late systolic MR murmur are commonly heard. [slideshare.net]

systolic murmur that is best heard at the mitral region and may radiate to the axilla. [amboss.com]

Left Atrial Ball Valve Thrombus

Left Atrial Ball-Valve Thrombus Mimicking Myxoma. A Case Report Abstract SUMMARY A 55-year-bld woman has been hospitalized with a complaint - of frequent syncopal attacks, especially when she lay over her back. She had no overt signs of heart failure and rhythm was atrial fibrillation. Preoperative[…] [dergi.omu.edu.tr]

Myxoid Transformation of the Mitral Valve

A murmur that lasts throughout the whole of systole is known as a holo-systolic murmur. [en.wikipedia.org]

Chordae tendineae rupture complicating the systolic click-late systolic murmur syndrome. [ncbi.nlm.nih.gov]

On physical examination, thrill along the left sternal edge, and a long systolic ejection murmur with late peak may be appreciated. [textbookofcardiology.org]

Interventricular Septum Aneurysm

Late systolic murmur: A clue to the diagnosis of aneurysm of the membranous ventricular septum. Chest 1971;60:283-6. [ PUBMED ] 8. [annals.in]

A soft systolic murmur is the usual reason for referral. [rjmatthewsmd.com]

systolic murmur heard primarily along the left sternal border could give a clue to the diagnosis of aneurysm of the membranous ventricular septum. [7] Yavuz et al ., suggested [annals.in]

Myxomatous Mitral Valve Prolapse 3

systolic murmur that is best heard at the mitral region and may radiate to the axilla. [amboss.com]

Late systolic murmurs and non-ejection (“mid-late”) systolic clicks. An analysis of 90 patients. Br Heart J. 1968;30:203–18. 17. [aafp.org]

MVP with MR causes a click with a late-systolic MR murmur. [msdmanuals.com]

Myxomatous Mitral Valve Prolapse 2

In the 1960s, Reid 7 and Barlow and colleagues 1 proposed that mid to late systolic clicks and apical late systolic murmurs were of mitral valvar origin. [heart.bmj.com]

Late systolic murmurs and non-ejection (“mid-late”) systolic clicks. An analysis of 90 patients. Br Heart J. 1968;30:203–18. 17. [aafp.org]

MVP with MR causes a click with a late-systolic MR murmur. [merckmanuals.com]

Cantalamessa Baldini Ambrosi Syndrome

Most patients (approximately 80%) with MVP have a midsystolic click followed by a late systolic murmur; however, echocardiography is needed to confirm the diagnosis. [accesspediatrics.mhmedical.com]

Neurocirculatory Asthenia

Group holosystolic murmur intracardiac isolated Jeresaty late systolic murmur left atrium left ventricle left ventricular left ventriculogram Marfan's syndrome midsystolic [books.google.com]

Late systolic murmurs and non-ejection ("mid-late") systolic clicks. An analysis of 90 patients. [ncbi.nlm.nih.gov]

الصفحات المحددة الصفحة 31 الصفحة 73 الصفحة 47 الصفحة 68 الصفحة 46 المحتويات Late Systolic Murmurs and NonEjection MidLate Systolic Clicks Clinical and Cineangiocardiographic [books.google.com]

Eye Defects - Arachnodactyly - Cardiopathy Syndrome

[…] of aortic regurgitation, listen for ejection click and late systolic murmur of mitral valve prolapse. [ptpaces.wordpress.com]

Redundant cusps and chordae tendineae may lead to mitral valve prolapse or regurgitation; mitral valve prolapse may cause a systolic click and a late systolic murmur or, in [merckmanuals.com]

[…] collapsing pulse, ask for a blood pressure, feel for their apex, sit them forward and ask them to take a deep breath in and out and hold it and listen for an early diastolic murmur [ptpaces.wordpress.com]

Left Ventricular Outflow Obstruction

systolic murmur over the praecordium Investigations ECHO: -> small LV cavity -> normal systolic function and no RWMA -> AVR functioning well -> flow acceleration noted in [lifeinthefastlane.com]

Examination Classic examination findings are a forceful apex beat, with double impulse if the left ventricular outflow tract is obstructed and a late ejection systolic murmur [patient.info]

Severe forms of SAS result in an increased gradient across the area of stenosis and are usually evidenced on physical examination by a harsh late-peaking systolic murmur, [circ.ahajournals.org]

Straight Back Syndrome

systolic ejection murmur; it is asymptomatic but may be misinterpreted by the examiner, causing an otherwise healthy person to become a cardiac 'cripple' straight back syndrome [medical-dictionary.thefreedictionary.com]

[…] volume index and LV end-systolic dimension, occurs even with isolated late systolic MR murmur similar to that seen with pan-systolic MR murmur. [25] Patients who are older [emedicine.medscape.com]

[…] and right hilum, displacing heart to left, simulating cardiomegaly Associations ASD, scoliosis; it may cause mild pulmonary vein obstruction and dilation, evoking a harsh late [medical-dictionary.thefreedictionary.com]

Mitral Valve Stenosis

Late systolic murmur late-systolic-murmur.mp3 Mitral regurgiation Holosystolic murmur Mitral regurgiation Late systolic murmur, Mitral regurgiation Mid systolic click Mitral [play.google.com]

murmur Coarctation of the aorta Complet heart block Slow heart rate,varying first-sound.mp3 Early systolic murmur Ebstein anomaly functional or innocent murmur-venous hum [play.google.com]

[…] insufficiency Aortic septal defect Aortic Stenosis Aortic stenosis Opening snap of aortic valve, Aortic stenosis Atrial septal defect Abnormal splitting of Coarctation of aorta Systolic [play.google.com]

Tricuspid Valve Insufficiency

Tricuspid valve prolapse may present with a midsystolic click and a late systolic murmur, most prominent at the lower left sternal border. [patient.info]

Ostium Primum Atrial Septal Defect

– of pulmonary regurgitation if pulmonary hypertension 13. • Late systolic murmur – occurs in Ostium secundum • Murmur of mitral incompetence – in Primum defect  Small peripheral [slideshare.net]

[…] at left sternal border with a late systolic accentuation at the upper left sternal edge. [enotes.tripod.com]

Murmurs • Pulmonary ejection systolic murmur – Increased pulmonary flow • Tricuspid murmur – is heard over left sternal edge louder on inspiration • Graham-Steell murmur [slideshare.net]

Tricuspid Stenosis

Tricuspid valve prolapse may present with a midsystolic click and a late systolic murmur, most prominent at the lower left sternal border. [patient.info]

Am J Cardiol 55: 432–438 Google Scholar Ronan JA, Perloff JK, Harrey WP (1965) Systolic clicks and late systolic murmur. [link.springer.com]

On physical examination, thrill along the left sternal edge, and a long systolic ejection murmur with late peak may be appreciated. [textbookofcardiology.org]

Atrioventricular Septal Defect

A soft systolic murmur is the usual reason for referral. [rjmatthewsmd.com]

Marfan Syndrome Type 2

Review Topic QID: 109230 1 Holosystolic, high-pitched blowing murmur at the lower left sternal border 2 Late systolic crescendo murmur at the apex with mid-systolic click [medbullets.com]

[…] click followed by a late systolic murmur aortic regurgitation diastolic murmur mitral regurgitation high-pitched holosystolic murmur Imaging Transthoracic echocardiography [medbullets.com]

[…] wrist ( wrist sign ) pectus carinatum or excavatum scoliosis hypermobile joints ocular subluxation of lenses (superior and temporal) cardiovascular mitral valve prolapse mid-systolic [medbullets.com]

Marfan Syndrome

Review Topic | Tested Concept QID: 109230 1 Holosystolic, high-pitched blowing murmur at the lower left sternal border 2 Late systolic crescendo murmur at the apex with mid-systolic [step2.medbullets.com]

Redundant cusps and chordae tendineae may lead to mitral valve prolapse or regurgitation; mitral valve prolapse may cause a systolic click and a late systolic murmur or, in [merckmanuals.com]

Right Atrial Hypertrophy

Tricuspid valve prolapse may present with a midsystolic click and a late systolic murmur, most prominent at the lower left sternal border. [patient.info]

Ostium Secundum Atrial Septal Defect

A soft systolic murmur is the usual reason for referral. [rjmatthewsmd.com]

Mitral Valve Atresia

Tricuspid valve prolapse may present with a midsystolic click and a late systolic murmur, most prominent at the lower left sternal border. [patient.info]

Acute Aortic Regurgitation

Am J Cardiol 55: 432–438 Google Scholar Ronan JA, Perloff JK, Harrey WP (1965) Systolic clicks and late systolic murmur. [link.springer.com]

On physical examination, thrill along the left sternal edge, and a long systolic ejection murmur with late peak may be appreciated. [textbookofcardiology.org]

Stroke 16: 219 PubMed Google Scholar Barlow JB, Bosman CK, Pocock WA et al. (1968) Late systolic murmur and non ejective (mid-late) systolic clicks: Br Heart J 3o: 203 Google [link.springer.com]

Atrial Septal Defect 9

A soft systolic murmur is the usual reason for referral. [rjmatthewsmd.com]

Tricuspid Valve Disease

Tricuspid valve prolapse may present with a midsystolic click and a late systolic murmur, most prominent at the lower left sternal border. [patient.info]