Late Systolic Murmur: Possible Causes & Differential Diagnoses

Mitral Valve Prolapse Syndrome
Systolic Murmur Late Systolic Murmur

Mid-systolic click and late-systolic murmur are characteristic signs and should prompt further cardiological evaluation. […] This click corresponds to displacement of one or both mitral cusps into the left atrium and may be followed by a late-systolic murmur that indicates mitral regurgitation.^[1]
Mitral Valve Insufficiency
Systolic Murmur Late Systolic Murmur

Patients with mitral valve prolapse may have a holosystolic murmur or often a mid-to-late systolic click and a late systolic murmur.^[2]
Left Atrial Ball Valve Thrombus
Late Systolic Murmur
Chordae Tendinae Rupture
Systolic Murmur Late Systolic Murmur
Papillary Muscle Disorder
Systolic Murmur Late Systolic Murmur
Mitral Valve Disease
Late Systolic Murmur

Mitral valve diseases include stenosis, regurgitation, and prolapse. These diseases can progress and evolve into serious life-threatening complications such as heart failure and even death. The dynamic mitral valve is prone to three diseases, which are known as mitral stenosis (MS), mitral regurgitation (MR), and…^[3]
Papillary Muscle Dysfunction
Systolic Murmur Late Systolic Murmur
Mitral Valve Incompetence
Systolic Murmur

Patients with mitral valve prolapse may have a holosystolic murmur or often a mid-to-late systolic click and a late systolic murmur.^[4]
Malignant Carcinoid Syndrome
Systolic Murmur Pulmonary Systolic Murmur

Carcinoids are neuroendocrine tumors most commonly originating from the midgut. Primary tumors and possibly existing metastases produce a variety of hormones and hormone-like mediators that provoke systemic symptoms like flushing, diarrhea and cardiac insufficiency - the entirety of these symptoms is referred to…^[5]
Severe Anemia
Systolic Murmur

Possible Causes for Late Systolic Murmur in USA

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References