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946 Possible Causes for LDL Increased

  • Hypercholesterolemia

    Abstract: Familial hypercholesterolemia (FH) is an inherited metabolic disorder characterized by high levels of plasma low density lipoproteins (LDL) and an increased risk[doi.org] High levels of “bad” LDL cholesterol — especially small, dense oxidized LDL — have been linked to increased risk of heart disease.[healthline.com] On one hand, it can be beneficial by increasing the good or HDL cholesterol. On the other, it may be harmful by increasing the bad cholesterol or LDL.[coalition4healthcare.org]

  • Heterozygous Familial Hypercholesterolemia

    Low-density-lipoprotein (LDL) cholesterol decreased 55 per cent with colestipol and niacin, whereas highdensity-lipoprotein (HDL) cholesterol increased.[nejm.org] LDL receptor expression is partly – half the equation is how do you increase the number of LDL receptors that you make from that one good gene?[chrismasterjohnphd.com] By reducing hepatic cholesterol synthesis, these drugs enhance LDL receptor activity in the liver, which, in turn, increases LDL catabolism and decreases LDL-cholesterol production[ommbid.mhmedical.com]

  • Familial Hypercholesterolemia

    LDL, decreased HDL, increased triglycerides Alcohol excess Increased triglycerides, increased HDL Cholestasis Increased LDL, increased total chol Diabetes Mellitus Hyperlipidaemia[diapedia.org] […] levels of low-density lipoprotein cholesterol (LDL-C) and increased risk for premature coronary heart disease (CHD).[ncbi.nlm.nih.gov] From Jump to: navigation , search Contents 1 Etiology 2 Laboratory 3 Management 4 More General Terms 5 References Etiology defect in LDL receptor Laboratory increase in LDL[anvita.info]

  • Coronary Atherosclerosis

    Increased LDL levels were observed over time in patients with the -7673G A polymorphism of the ApoB gene.[ncbi.nlm.nih.gov] But trans fatty acids not only increase LDL cholesterol levels, they also reduce HDL cholesterol levels.[web.archive.org] Lose Weight Obesity results not only in increased LDL cholesterol but also in reduced HDL cholesterol.[heartdisease.about.com]

  • Arteriosclerosis

    These fats actually help to lower LDL and increase levels of HDL the good cholesterol. These fats come from oily fish such as salmon, tuna and trout.[avogel.ca] Cholesterol lowering medications (statins) reduce the undesirable low-density lipoproteins (LDL) and increase levels of desirable high-density lipoproteins (HDL), thereby[naturalremedies.org] In patients with marked hypertriglyceridemia, LDL cholesterol levels may increase, which likely reflects the ability of the LDL receptor to clear the increased LDL generated[emedicine.com]

  • Growth Hormone Deficiency

    […] in rate of fracture in middle age and beyond changes in blood cholesterol concentrations (increase in LDL and decrease in HDL) excessive tiredness anxiety and depression[pituitary.org.uk] , compared to the control group (median increase in LDL-CH, CH and TG were 0.1 mmol/l, 0.1 mmol/l and 0.3mmol/l, respectively).[ncbi.nlm.nih.gov] […] feelings of social isolation reduction in 'quality of life' increased sensitivity to cold or heat[pituitary.org.uk]

  • Homozygous Familial Hypercholesterolemia

    This mutation can lead to increased serum LDL, and subsequently to premature coronary artery disease.[ncbi.nlm.nih.gov] […] in extremely elevated plasma LDL cholesterol (LDL-C) and increased risk of atherosclerosis, coronary heart disease, and premature death.[ncbi.nlm.nih.gov] In the survival benefit analysis, starting lomitapide at age 18 years and reducing LDL-cholesterol by 3.3 mmol/L from baseline would increase life expectancy by 11.2 years[ncbi.nlm.nih.gov]

  • Hyperlipoproteinemia Type 2b

    From More Specific Terms familial combined hyperlipidemia Etiology familial form ( familial combined hyperlipidemia ) defect in LDL receptor Laboratory increase in LDL cholesterol[anvita.info] Type 1- hyperchylomicronemia- increased chylomicrons due to lipoprotien lipase defficiency Type 2a- Hypercholesterolemia- increased LDL due to decreased LDL receptors Type[usmleforum.com] […] production of VLDL - VLDL matures to LDL - certain increase in LDL causes VLDL increase leading to hyperCHOLESTEROLemia and hyperTRIGLYCERIDEmia respectively dys beta lipoprotein[quizlet.com]

  • Cholesterol Ester Storage Disease

    This explains the laboratory results detailed above: permanent hypercholesterolemia, increased LDL cholesterol and decreased HDL cholesterol.[symptoma.com] This results in an increase in the number and activity of LDL receptors on the hepatocyte membrane, and the rate of LDL catabolism increases.[lipidworld.biomedcentral.com] In a CESD patient, the increased clearance of CE-trafficking LDL has the potential, theoretically, to increase cellular CE, adding to hepatotoxicity.[raredr.com]

  • Niemann-Pick Disease Type B

    LDL cholesterol Increased triglycerides Decreased HDL cholesterol Etiology Caused by mutations in the acid lysosomal sphingomyelin phosphodiesterase-1 gene (SMPD1) (MIM.607608[humpath.com] […] plasma triglycerides Increased serum triglycerides Increased triglycerides [ more ] 0002155 Increased LDL cholesterol concentration Increased circulating LDL level Increased[rarediseases.info.nih.gov] LDL-c, and hypertriglyceridemia) Plain radiograph chest reticulonodular pattern which usually starts in the lower lobes calcified micronodules skeletal short stature with[radiopaedia.org]

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