Possible Causes for Lead Encephalopathy in USA

  • Lead Poisoning
    Diffuse Encephalopathy Lead Encephalopathy

    Lead poisoning is a condition, characterized by increased levels of lead in the body. Such a phenomenon causes development of incapacitating symptoms, which can turn life threatening, if treatment is not initiated on time. Signs and symptoms of lead poisoning are not evident, unless large amounts of lead have been…[1]

  • Lead Poisoning in Children
    Lead Encephalopathy

    Lead poisoning in children still presents as a significant issue worldwide, with the main mode of exposure being chips and dust from lead-based paint. CNS impairment is the most prominent and causes a variety of symptoms depending on the severity of exposure. The diagnosis is made by confirming increased levels of…[2]

  • AMACR Deficiency

    α-Methylacyl-CoA racemase (AMACR) deficiency is an inherited condition that leads to functional impairment of the cellular peroxisomes and elevated levels of pristanic acid, phytanic acid, and C27-bile acid intermediates. AMACR deficiency manifests with a varying clinical picture. A more definitive establishment of a…[3]

  • Lyme Neuroborreliosis

    Lyme neuroborreliosis is a late manifestation of an infection by Borrelia spp., a tick-borne bacterial pathogen that is known for causing Lyme disease and a range of clinical syndromes. The ailment is primarily seen during the summer months and symptoms range from headaches and facial nerve palsy to severe sensory…[4]

  • Methylmalonic Acidemia

    Methylmalonic acidemia (MMA) is a rare metabolic disorder that results as a consequence of the accumulation of toxic levels of methylmalonic acid. This rare condition is associated with serious sequelae such as neurological manifestations and/or even organ failure. The age of onset and clinical picture are correlated…[5]

  • Chronic Eosinophilic Leukemia

    Chronic eosinophilic leukemia is a rare myeloid malignancy characterized by primary eosinophilia and progressive organ damage. Diagnosis of this disease and distinction from idiopathic hypereosinophilic syndrome requires the detection of determined mutations, demonstration of clonality of eosinophils, or observation of…[6]

  • Congenital Acquired Immune Deficiency Syndrome

    Congenital acquired immune deficiency syndrome occurs due to mother-to-child transmission of HIV in utero, during delivery or breast-feeding. Depending on various factors, around 5-50% of children born to HIV+ mothers are infected. The diagnosis is made by a combination of clinical and immunological criteria, while…[7]

  • Carbamoyl Phosphate Synthase Deficiency

    Carbamoyl phosphate synthetase deficiency is a urea cycle disorder inherited as an autosomal recessive trait. Hyperammonemia is the clinical hallmark of the disease and results from the reduced synthesis of carbamoyl phosphate from ammonia and bicarbonate. Neonatal-onset CPSI deficiency is the most common form of…[8]

  • Hyperornithinemia-Hyperammonemia-Homocitrullinuria Syndrome

    Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome is a very rare urea cycle disorder. It is provoked by a mutation of the gene encoding for the mitochondrial ornithine transporter 1, which plays a crucial role in citrulline and ornithine transport across the mitochondrial membrane. Clinical presentation and…[9]

  • Propionic Acidemia

    Propionic acidemia is a rare metabolic disorder characterized by an accumulation of propionyl acids in blood, tissues, and urine. This condition interferes with other metabolic processes and may cause life-threatening ketoacidosis, cardiomyopathy, and encephalopathy. Neonatal-onset PA largely resembles hyperammonemic…[10]

Similar symptoms


  1. Lead Poisoning, Symptoma
  2. Lead Poisoning in Children, Symptoma
  3. AMACR Deficiency, Symptoma
  4. Lyme Neuroborreliosis, Symptoma
  5. Methylmalonic Acidemia, Symptoma
  6. Chronic Eosinophilic Leukemia, Symptoma
  7. Congenital Acquired Immune Deficiency Syndrome, Symptoma
  8. Carbamoyl Phosphate Synthase Deficiency, Symptoma
  9. Hyperornithinemia-Hyperammonemia-Homocitrullinuria Syndrome, Symptoma
  10. Propionic Acidemia, Symptoma