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88 Possible Causes for Left Shift of WBC, Thrombocytopenia

  • Familial Myelofibrosis

    Blood counts generally reveal normocytic, normochromic anemia, leukopenia, and thrombocytopenia.[symptoma.com] Thus, patients suffering from myelofibrosis eventually develop anemia, leukopenia, and thrombocytopenia.[symptoma.com] Because platelets play an essential role in homeostasis, thrombocytopenia results in easy bruising and a propensity to bleed.[symptoma.com]

  • Primary Myelofibrosis

    Six weeks later, he developed grade 4 thrombocytopenia and grade 3 anemia.[ncbi.nlm.nih.gov] Severe side effects resulting from this therapy, such as leukocytopenia or thrombocytopenia, were never observed.[ncbi.nlm.nih.gov] We report a patient with seropositive rheumatoid arthritis with concurrent primary myelofibrosis, who had transfusion-dependent anemia and moderate thrombocytopenia that reversed[ncbi.nlm.nih.gov]

  • Chronic Neutrophilic Leukemia

    Thrombocytopenia was refractory to medical treatment and, in part, was attributed to splenic sequestration.[ncbi.nlm.nih.gov] Left shifted neutrophilia* Left shifted neutrophilia Monocytosis, may have left shifted neutrophilia Neutrophilia B lood basophils Increased Not increased Not increased Not[surgpathcriteria.stanford.edu] Bleeding is reportedly one of the major causes of death in patients with chronic neutrophilic leukemia (CNL), but thrombocytopenia, abnormal platelet functions, or coagulopathy[ncbi.nlm.nih.gov]

  • Atypical Chronic Myeloid Leukemia

    We report a 49-year-old Caucasian female, who presented with extreme leukocytosis (white blood cells of 148,300/µL) with left shift, severe anemia, and thrombocytopenia.[ncbi.nlm.nih.gov] Left shifted neutrophilia* Left shifted neutrophilia Monocytosis, may have left shifted neutrophilia Neutrophilia B lood basophils Increased Not increased Not increased Not[surgpathcriteria.stanford.edu] All but one case showed, at time of diagnosis, leukocytosis (median WBC was 36 x 10(9)/l), 55% had moderate anemia and 36% had thrombocytopenia.[ncbi.nlm.nih.gov]

  • Splenitis

    Myelodysplastic Syndrome ...the condition “...A blood count can show the following signs: neutropenia (low white blood cell count); anemia (low red blood cell count); thrombocytopenia[diagnose-me.com] Blood analysis revealed a moderate neutrophilia (43,000 WBC) with a left shift. Blood chemistry was normal.[sonopath.com]

  • Leukemoid Reaction

    There was laboratory evidence of anemia, thrombocytopenia and a leukemoid reaction.[ncbi.nlm.nih.gov] This is known as a 'left shift'. A very high WBC count ( 50,000) with pronounced left shift that is not a leukemia is known as a "leukemoid reaction".[library.med.utah.edu] Cytomegalovirus (CMV) infection causes a multisystem disease, and symptomatic infants generally present with intrauterine growth restriction, hepatosplenomegaly, cholestasis, rash, thrombocytopenia[ncbi.nlm.nih.gov]

  • Alcoholic Hepatitis

    These findings suggest that PAIgG may have been involved in the development of thrombocytopenia in this patient.[ncbi.nlm.nih.gov] 12,000 with left shift Hepatic encephalopathy Hepatic systolic bruit Maddrey discriminant factor 32 [4] , [5] Exclusion Criteria Concomitant bacterial infection Active GI[wikijournalclub.org] […] based on clinical symptoms and laboratory finding alone including elevated AST/ALT (but may 300 IU/mL), AST ALT of 2, Total serum bilirubin 5mg/deciliter, elevated INR, thrombocytopenia[bloodjournal.org]

  • Leukoerythroblastic Anemia

    Acute Erythroblastic Leukemia Anemia, X-Linked, without Thrombocytopenia aplastic anemia Aplastic Anemia, Idiopathic Bone Marrow Failure Syndromes chronic myeloid leukemia[rgd.mcw.edu] , left shifted, basophilia, eosinophilia, rarely monocytosis Normal or , /- basophils, (leukoerythroblastic ini fibrotic stage) granulocytes if leukoerythroblastic Normal[surgpathcriteria.stanford.edu] […] who presented seven years following apparently successful surgery and adjuvant chemo-radio-therapy, with blood film findings of microangiopathic hemolytic anemia (MAHA), thrombocytopenia[ncbi.nlm.nih.gov]

  • Cervical Cancer

    Hematotoxic adverse events observed during the chemotherapy were grade 4 neutropenia, grade 3 anemia, and grade 4 thrombocytopenia, and the non-hematotoxic adverse events[ncbi.nlm.nih.gov] After paclitaxel injection, the WBC count increased to 70.37*109/L. Bone marrow aspirates and biopsy showed left-shift neutrophilia, which confirmed leukemoid reaction.[ncbi.nlm.nih.gov]

  • Thrombocytopenia-Absent Radius Syndrome

    The thrombocytopenia-absent radius syndrome, a rare medical entity, is distinguished by bilateral aplasia of the radius on both arms and thrombocytopenia.[symptoma.com] Leukocytosis - WBC greater than 35 x 10 9 /L with left shift, leukaemoid reaction. Anaemia secondary to bleeding.[patient.info] Thrombocytopenia-absent radius (TAR) syndrome is a relatively uncommon condition characterized by absent radii with the presence of thumbs and congenital or early-onset thrombocytopenia[ncbi.nlm.nih.gov]

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