Left Ventriculomegaly: Causes & Reasons

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Possible Causes for Left Ventriculomegaly

Familial Atrial Fibrillation Type 2

BACKGROUND: Loss-of-function mutations in the gene KCNQ1 encoding the Kv7.1 K(+) channel cause long QT syndrome type 1 (LQT1), whereas gain-of-function mutations are associated with short QT syndrome as well as familial atrial fibrillation (FAF). However, KCNQ1 mutation pleiotropy, which is capable of expressing both[…] [ncbi.nlm.nih.gov]

ZTTK Syndrome

However, both cases presented also with exceptional symptoms such as in case 1 ventriculomegaly and asymmetry of ventricles, hypoplastic left heart syndrome (HLHS), intellectual [unboundmedicine.com]

Sotos Syndrome

The pregnancy was uneventful until 27 weeks of gestation when left ventriculomegaly was first noted. [ncbi.nlm.nih.gov]

At 31 weeks of gestation, polyhydramnios, macrocephaly, and ventriculomegaly were prominent on ultrasound, and left pyelectasis and bilateral ventriculomegaly were diagnosed [ncbi.nlm.nih.gov]

Pyridoxine Dependency Syndrome

Pregnancy was remarkable for a left lateral ventriculomegaly identified at 22 weeks’ gestation on fetal ultrasound. [pediatrics.aappublications.org]

Foster-Kennedy Syndrome

[…] lateral ventriculomegaly with downward displacement of the gyrus rectus, resulting in left optic nerve compression (A), due to a left intraventricular mass (B). [neurology.org]

The left cavernous sinus seemed to be invaded by the tumor. The diagnosis was consistent with sphenoid ridge meningioma (Fig. 2D). [healio.com]

[…] nerve. 1 Figure Optic nerve compression by gyrus rectus and intraventricular mass causing displacement of gyrus rectus Coronal T2-weighted orbital and brain MRI reveals left [neurology.org]

Waisman Syndrome

Cranial computed tomography revealed left ventriculomegaly, more pronounced in the occipital horn suggesting mild atrophy of the left parietal lobe. [pedneur.com]

Abstract We report a 12-year-old boy with multiple lentigines (Leopard) syndrome who was evaluated for learning difficulties and Gerstmann tetrad syndrome (i.e., dyscalculia, left-right [pedneur.com]

Vein of Galen Aneurysm

B, T2-weighted axial MRI at 2 months of age before embolization shows significant enlargement of the central vein and ventriculomegaly. [clinicalgate.com]

Posttreatment echocardiogram showed improvement in the left ventricular function. [surgicalneurologyint.com]

Left vertebral artery angiograms in the posteroanterior (PA) ( C ) and lateral ( D ) views show a mural-type vein of Galen aneurysmal malformation (VGAM) supplied by the right [clinicalgate.com]

Hemimegalencephaly

However, it was an unusual variant of this syndrome because the patient had left facial hemihypertrophy, left hemimegalencephaly and ipsilateral ventriculomegaly. [ncbi.nlm.nih.gov]

Klippel-Trenaunay-Weber Syndrome

However, it was an unusual variant of this syndrome because the patient had left facial hemihypertrophy, left hemimegalencephaly and ipsilateral ventriculomegaly. [ncbi.nlm.nih.gov]

Recombinant Chromosome 8 Syndrome

(left 7.1 mm and right 6.0 mm) (seen in Fig. 3a, b and c). [molecularcytogenetics.biomedcentral.com]

Ultrasound findings at 21 weeks revealed IUGR, hydrothorax (4 mm) and ascites (5 mm), increased nuchal fold (NF 12.7 mm, septation was seen), hydrothorax and bilateral mild ventriculomegaly [molecularcytogenetics.biomedcentral.com]

Oculootoradial Syndrome

Brain and spinal cord MRI showed a Galassi type 2 arachnoid cyst in the left medial cranial fossa, supratentorial ventriculomegaly, focal thickening of the infundibular stem [peertechzpublications.com]

Mucopolysaccharidosis Type 3

Axial T2 ( D ) and right ( E ) and left ( F ) sagittal T2 images show narrowing of the optic canals ( arrows ), hyperintensities in perioptic spaces, and brain atrophy. [ajnr.org]

C, Coronal T2 image shows hyperintensities in periventricular white matter ( arrows ) and perioptic spaces ( arrowheads ), ventriculomegaly, and brain atrophy. [ajnr.org]

Axial T2 ( A ) and axial T2 FLAIR ( B ) images show periventricular white matter hyperintensities ( arrows ), prominent Virchow-Robin spaces ( arrowheads ), ventriculomegaly [ajnr.org]

Intestinal Obstruction

and hypoplastic left heart. [ncbi.nlm.nih.gov]

[…] year-old, primigravid woman underwent cord blood sampling at 31 weeks of gestation because of prenatal ultrasound findings of polyhydramnios, intestinal obstruction, right ventriculomegaly [ncbi.nlm.nih.gov]

LEOPARD Syndrome

Cranial computed tomography revealed left ventriculomegaly, more pronounced in the occipital horn suggesting mild atrophy of the left parietal lobe. [ncbi.nlm.nih.gov]

We report a 12-year-old boy with multiple lentigines (Leopard) syndrome who was evaluated for learning difficulties and Gerstmann tetrad syndrome (i.e., dyscalculia, left-right [ncbi.nlm.nih.gov]

Congenital Pulmonary Valve Stenosis

Parasternal long axis view revealed ventriculomegaly as massive hypertrophy of right ventricle, hypertrophy of left ventricle with features of hypertrophic cardiomyopathy [scirp.org]

The dilated right ventricle is rounded rather than boot-shaped and its apex is above the left hemidiaphragm. Figure 7. [scirp.org]

Showing “ventriculomegaly”―massive RVH (right ventricular hypertrophy). Figure 8. Parasternal long axis view showing HCM (hypertrophic cardiomyopathy). Figure 9. [scirp.org]

Crane-Heise Syndrome

Repeat ultrasound at 13 weeks revealed gastroschisis, scoliosis, dangling choroid plexus, and left clubbed foot. [ashg.org]

Ultrasound at 16 weeks confirmed those observations and added cleft lip and palate, and bilateral ventriculomegaly. [ashg.org]

Subependymal Giant Cell Astrocytoma

ventriculomegaly. [thejns.org]

Axial (C) and coronal (D) postcontrast MR images showing obliteration of the left lateral ventricle with avidly enhancing tumor associated with mild ventriculomegaly. [thejns.org]

Neuroimaging demonstrated a cystic, multilobulated enhancing mass within the left lateral ventricle adjacent to the foramen of Monro, associated with contralateral ventriculomegaly [thejns.org]

Periventricular Leukomalacia

At 40 weeks postmenstrual age, in the right (E) and left (F) parasagittal views, the cyst is no longer seen and ventriculomegaly is only present on the left. [fn.bmj.com]

At 6 weeks of age, the coronal (C) and left parasagittal (D) views show a localised left sided occipital cyst (arrowhead) with associated mild ventriculomegaly. [fn.bmj.com]

The T2 weighted SE sequence shows asymmetrical ventriculomegaly, more pronounced and irregular on the left, and bilateral gliosis (courtesy of Dr Bouman, Deventer). [fn.bmj.com]

Smith-Magenis Syndrome

The CMA result of Fetus 1, which had increased NT, mild lateral ventriculomegaly, tricuspid regurgitation, and right aortic arch with left ductus arteriosus, revealed a de [ncbi.nlm.nih.gov]

Mucopolysaccharidosis Type 4

Axial T2 ( D ) and right ( E ) and left ( F ) sagittal T2 images show narrowing of the optic canals ( arrows ), hyperintensities in perioptic spaces, and brain atrophy. [ajnr.org]

C, Coronal T2 image shows hyperintensities in periventricular white matter ( arrows ) and perioptic spaces ( arrowheads ), ventriculomegaly, and brain atrophy. [ajnr.org]

Axial T2 ( A ) and axial T2 FLAIR ( B ) images show periventricular white matter hyperintensities ( arrows ), prominent Virchow-Robin spaces ( arrowheads ), ventriculomegaly [ajnr.org]

Coats Plus Syndrome

(left), Colpocehaly, Hypoplasia of the septum pellucidum and the cerebellar vermis, plus Polymicrogyria. [rarediseasedayaustralia.com.au]

Read More My unique star Imogen Imogen has hydrocephalus and needed a shunt to release the blocked fluid on the brain, Corpus callosum hypoplasia with ventriculomegaly, Plagiocephaly [rarediseasedayaustralia.com.au]

Renal Teratoma

Central Nervous System Microcephaly Retrognathia Ventriculomegaly Brain Atrophy Dandy-Walker Syndrome Cerebellar asymmetry Encephalocele Spina Bifida Heart Ventricular septal [fetal.com]

[…] defect Endocardial cushion defect Hypoplastic Left Ventricle Tetralogy of Fallot Renal System Hydronephrosis Renal Agenesis Multicystic Kidney Renal Dysplasia Abdominal Cavity [fetal.com]

Acalvaria

Exclusion of fetal ventriculomegaly with a single measurement: the width of the lateral ventricular atrium. Radiology 1988; 169:711-714. ‎ [books.google.ro]

[…] defects include: • transposition of the great vessels or arteries — a defect in which the aorta arises from the right ventricle and the pulmonary artery arises from the left [books.google.ro]

Pilocytic Astrocytoma

Visual acuity was 6/6 on the right and 6/9 on the left with a left relative afferent pupillary defect, bilateral papilloedema and left lateral rectus palsy. [jnnp.bmj.com]

MRI showed ventriculomegaly. Lumbar puncture revealed normal constituents with an opening pressure of 60 cm H 2 O. [jnnp.bmj.com]

A 30 year old lady presented in 2012 with a three month history of headaches, nausea and vomiting, two weeks of blurred vision and one week of double vision on looking left [jnnp.bmj.com]

Mucopolysaccharidosis Type 2

Axial T2 (D) and right (E) and left (F) sagittal T2 images show narrowing of the optic canals (arrows), hyperintensities in perioptic spaces, and brain atrophy. [ajnr.org]

C, Coronal T2 image shows hyperintensities in periventricular white matter (arrows) and perioptic spaces (arrowheads), ventriculomegaly, and brain atrophy. [ajnr.org]

Axial T2 (A) and axial T2 FLAIR (B) images show periventricular white matter hyperintensities (arrows), prominent Virchow-Robin spaces (arrowheads), ventriculomegaly, and [ajnr.org]

Frontonasal Dysplasia

Commonly described features include 8,9 : face and head hypertelorism c left lip cleft palate absence of the nasal tip widow's peak frontal hairline central nervous system [radiopaedia.org]

[…] cranium bifidum occultum (cleft skull) ethmoidal cephalocele agenesis of the corpus callosum ventriculomegaly interhemispheric cyst The exact pathogenesis is unknown but [radiopaedia.org]

Trisomy 9

Abdominal ultrasound revealed a left bladder diverticulum. Brain ultrasound revealed partial agenesis of the corpus callosum, no ventriculomegaly. [ashg.org]

Congenital Cytomegalovirus Infection

An ultrasound examination revealed asymmetric intracranial ventriculomegaly with the left lateral ventricle larger than the right and strands visible across both ventricles [doi.org]

Head CT and ultrasound were unremarkable except for ventriculomegaly. Ophthalmologic exam showed no evidence of chorioretinitis. [nature.com]

Moinuddin et al. reported an infant at 35 weeks of gestation with congenital CMV who was diagnosed as having right parietal and temporal hemorrhages with ventriculomegaly [doi.org]

Bilateral Multicystic Dysplastic Kidney

Fetus 65 presented with the clinical phenotypes of spina bifida, ventriculomegaly and left MCDK. [academic.oup.com]

Aberrant Right Subclavian Artery

[…] one showed persistent left superior vena cava. [e-ultrasonography.org]

In three cases (10.7%), ARSA was accompanied by other cardiac malformations, including persistent left superior vena cava and aneurysmal dilatation of the proximal portion [e-ultrasonography.org]

Among the four live-born neonates with Down syndrome, three revealed several soft markers such as short long bone, echogenic bowel, and mild cerebral ventriculomegaly, and [e-ultrasonography.org]