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201 Possible Causes for Leg Edema, Severe Muscle Atrophy

  • Becker Muscular Dystrophy

    muscle atrophy Birth: Increases over weeks after birth Troponin I: Elevated above normal but not to levels in cardiac ischemia Liver enzymes 18 High AST, ALT & LDH Up to[neuromuscular.wustl.edu] At the age of 20 years, he developed sinus tachycardia, leg edema, coughing, and arterial hypotension.[ncbi.nlm.nih.gov] These symptoms are typically milder than the severe muscle weakness and atrophy seen in affected males.[ghr.nlm.nih.gov]

  • Cardiac Amyloidosis

    In severe cases atrophy vacuolization, or even complete loss of muscle fibers may occur.[histopathology-india.net] A 64-year-old man was admitted to our hospital with leg edema and nocturnal dyspnea.[ncbi.nlm.nih.gov] Patients may experience symptoms such as foamy urine or leg edema.[nyp.org]

  • Myotonic Dystrophy

    His muscle biopsy showed marked increase of internalized nuclei, severely atrophic muscle fibers, muscle fiber necrosis and regeneration of isolated muscle fibers, architectural[ncbi.nlm.nih.gov] Ten months after the first TTS she developed dyspnea, leg edema, and anginal chest pain.[ncbi.nlm.nih.gov] Because the IL-6 pathway is involved in myocyte maturation and muscle atrophy, our results indicate that enhanced RNA toxicity contributes to severe CDM phenotypes through[ncbi.nlm.nih.gov]

  • Castleman Disease

    Some of the systemic symptoms include: Fever and night sweats Fatigue Loss of appetite Cachexia (weakness and wasting of the body, muscle atrophy, unintended weight loss)[cdcn.org] […] swelling (edema) Skin rashes The symptoms of MCD usually come on gradually.[sylvant.com] Continued… • Nausea and vomiting • Nerve damage that leads to numbness and weakness (neuropathy) • Leg swelling (edema) • Skin rashes • Secondary amyloidosis • Anemia is very[slideshare.net]

  • Renal Tubular Acidosis

    […] polyuria and polydipsia ; life-threatening volume depletion and hypotension Muscle atrophy , weakness, cramps , carpopedal spasm Failure to thrive , developmental delay Dysmorphic[amboss.com] However, a week after the first pulse of cyclophosphamide, the patient presented with a significant increase in legs edema and severe hyperkalemia.[ncbi.nlm.nih.gov] On physical examination, the patient was alert and oriented with mild pedal edema on both legs. There was no musculoskeletal pain or rash.[casesjournal.biomedcentral.com]

  • Rheumatoid Arthritis

    Stage III, severe rheumatoid arthritis, is marked by joint deformity, extensive muscle atrophy, soft tissue lesions, and definite bone and cartilage destruction.[medical-dictionary.thefreedictionary.com] Her physical examination revealed that she had bilateral pitting leg edema and periorbital edema. She was not pale or icteric.[ncbi.nlm.nih.gov] Stage II, moderate rheumatoid arthritis, incorporates cases in which there is evidence of some muscle atrophy and loss of mobility, in addition to x-ray findings.[medical-dictionary.thefreedictionary.com]

  • Neuralgia

    Tremors or spasm of the muscles may be present, and when the disease is long continued there may be atrophy, of the muscles. Neuralgia of the Genitalia and Rectum .[henriettes-herb.com] Thus, symptoms such as pain, edema, and skin hyperpigmentation on the left leg should be closely noted.[ncbi.nlm.nih.gov] —Of all neuralgias, none are more severe or harder to bear than neuralgia of the rectum and genitals.[henriettes-herb.com]

  • POEMS Syndrome

    […] interosseous muscle atrophy with glove and long boot hypoesthesia, proximal upper limb muscular strength at 4/5, distal dorsiflexion at 1/5 and plantar flexion at 3/5; in[omicsonline.org] We report on a 61-year-old female patient who initially presented with dyspnea and bilateral leg edema. Importantly, the patient had normal renal function.[ncbi.nlm.nih.gov] edema.[tib.eu]

  • Polyneuropathy

    Early motor signs include atrophy of the intrinsic foot muscles and ankle weakness.[bestpractice.bmj.com] Support stockings may be recommended for patients with leg edema (swelling).[ttrstudy.com] This is the reason why a muscle whose innervating axon is sectioned undergoes atrophy much more quickly and severely than one where the axon is intact, as in demyelination[dartmouth.edu]

  • Beriberi

    Muscles may become weak and waste away (atrophy). If the deficiency worsens, the arms are also affected. Wet beriberi Heart abnormalities develop.[merckmanuals.com] A probable case patient was defined as an individual who had at least two of the following characteristics: leg edema, weakness of the extremities, poor appetite, and dyspnea[ncbi.nlm.nih.gov] A 44-year-old male alcoholic patient from Morocco developed massive bilateral leg edema, a subacute sensorimotor neuropathy, and incontinence.[ncbi.nlm.nih.gov]

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