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37 Possible Causes for Leg Edema, Severe Peripheral Motor Neuropathy, Slow Pulse

  • Autonomic Neuropathy

    In addition to hypotension, many newly recognized syndromes can be attributed to cardiac autonomic neuropathy such as orthostatic tachycardia and bradycardia.[ncbi.nlm.nih.gov] […] and autonomic neuropathy.[ncbi.nlm.nih.gov] Edema Edema from venous insufficiency of the legs is due to sympathetic weakness while in the upright position.[drbuckeye.com]

  • Chronic Kidney Disease

    We report the case of a severe refractory MALA despite hemodialysis (HD) treatment, associated with hypoglycemia, hypothermia, and bradycardia in a neglected and thus untimely-recognized[ncbi.nlm.nih.gov] , peripheral sensory and motor neuropathies, muscle cramps, hyperreflexia, restless legs syndrome, and seizures (usually the result of hypertensive or metabolic encephalopathy[merckmanuals.com] Symptoms can include: Dry, itchy skin Nausea and vomiting Loss of appetite Fatigue Weight loss or weight gain Headaches Swelling in the legs (edema) Trouble sleeping Changes[health.ucsd.edu]

  • Diabetic Enteropathy

    IVIg: Hastens recovery; dose 2g/kg q month x3 Prognosis Slow recovery over 6 to 24 months after diabetic control Partial or complete Variant syndrome: Diabetic amyotrophy[neuromuscular.wustl.edu] Peripheral sensori-motor neuropathy  Distal, bilateral,symmetrical, stocking-glove distribution.  Symptoms range from numbness (“deadness”) to severe pain.[slideshare.net] There are basically three main types of edema associated with diabetes - macular edema, pulmonary edema, and foot and leg edema.[progressivehealth.com]

  • Polyneuropathy

    The typical course is very slow improvement. In this condition early judicious use of IVIG and pulse IV steroids may be helpful.[dartmouth.edu] Disease process involving several peripheral nerves (literal sense). 2.[medical-dictionary.thefreedictionary.com] Support stockings may be recommended for patients with leg edema (swelling).[ttrstudy.com]

  • Ischemic Peripheral Neuropathy

    […] abdominal pain, nausea, vomiting, malabsorption, fecal incontinence, gastroparesis, diarrhoea, constipation Cardiovascular system : disturbances of heart rate ( tachycardia, bradycardia[en.wikipedia.org] Diagnostic Approach The differential diagnosis of peripheral neuropathy is significantly narrowed by a focused clinical assessment that addresses several key issues ( Figure[aafp.org] Clinically, the manifestations as were seen in our patient include edema, varicose veins, and skin changes including stasis dermatitis and leg ulceration.[vasculardiseasemanagement.com]

  • Young Adult-Onset Distal Hereditary Motor Neuropathy

    The characteristic abnormalities are breath holding spells and apneas coupled with subtle bradycardia followed by exaggerated tachycardia.[frontiersin.org] The Charcot foot has been documented to occur as a consequence of various peripheral neuropathies; however, diabetic neuropathy has become the most common etiology.[care.diabetesjournals.org] Reports of cold feet, hair loss, or leg edema are common.[emedicine.medscape.com]

  • Alcoholic Neuropathy

    Reflex bradycardia in phase IV of the Valsalva maneuver and the variation coefficient of R-R intervals in the electrocardiogram were lower, indicating parasympathetic hypofunction[ncbi.nlm.nih.gov] Rarely if the neuropathy is severe patients may also develop peripheral weakness (motor symptoms).[braindiseases.info] Alcohol Causes Foot And Leg Swelling Drinking alcohol can cause lower limb swelling (called edema ).[footfiles.com]

  • Immune Thrombocytopenic Purpura

    […] in an otherwise healthy person Signs of chronic disease, infection, wasting, or poor nutrition indicate that the patient has another illness Vital signs: Hypertension and bradycardia[emedicine.medscape.com] Multiple variants of GBS exist, with acute motor and sensory axonal neuropathy (AMSAN) being the most severe.[ncbi.nlm.nih.gov] This patient does not have an infection of the legs.[journals.lww.com]

  • Acute Intermittent Porphyria

    Tetraplegia and chronic respiratory insufficiency developed, and the patient needed a pacemaker because of a symptomatic sinus bradycardia due to autonomic dysfunction.[ncbi.nlm.nih.gov] Acute attacks are characterized by severe abdominal pain, vomiting, constipation, hypertension, tachycardia, and bladder dysfunction, presumably due to an autonomic neuropathy[doi.org] O2 saturation 100%, hemodynamically stable, arterial blood pressure (ABP) 122/62mmHg, pulse 82/ min., generalized edemas, distended, meteoristic abdomen, diuresis present,[cyberleninka.org]

  • Churg-Strauss Syndrome

    […] see Slow rising pulse Anaemia see Anemia Anaemia (reduced erythropoeisis) see Red cell production reduced Anaemia secondary to bleeding see Anemia secondary to blood loss[diseasesdatabase.com] The majority of these cases (7/11) had sensory–motor mononeuritis multiplex neuropathy.[doi.org] Physical examination showed a wheeze, pretibial edema, and surrounding purpura.[ncbi.nlm.nih.gov]

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