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1,231 Possible Causes for Leg Edema, Swelling

  • Lipedema

    Lipedema is a condition characterized by diffuse, bilaterally symmetrical, painful swelling of the legs and buttocks.[ncbi.nlm.nih.gov] Lipedema of the legs; a syndrome characterized by fat legs and edema. Ann Intern Med. 1951;34:1243–1250. 6. Herpertz U.[journals.lww.com] Lipedema is a disproportionate, symmetrical fatty swelling characterized by pain and bruising existing almost exclusively among women.[ncbi.nlm.nih.gov]

  • Deep Vein Thrombosis

    On physical examination, the patient had increased warmth, edema, erythema, and tenderness in the left calf, with positive Homan's sign.[ncbi.nlm.nih.gov] A physical examination revealed bilateral leg edema.[ncbi.nlm.nih.gov] Damage to your veins from the blood clot reduces blood flow in the affected areas, which can cause: Persistent swelling of your legs (edema) Leg pain Skin discoloration Skin[mayoclinic.com]

  • Congestive Heart Failure

    This "right-sided" heart failure causes swelling (edema), usually in the feet and legs, and sometimes, in the abdomen.[healthcommunities.com] Complications include swelling of the legs (edema), kidney problems and fluid in the lungs.[hopkinsmedicine.org] Swelling (edema) often results. Typically, there’s swelling in the legs and ankles, but it can happen in other parts of the body, too.[cheyenneregional.org]

  • Heart Failure

    ( ascites ) from excess fluid Lower leg or foot swelling ( pedal edema ) Palpitations (sensation of fast or irregular heartbeat) A detailed medical history and physical examination[jama.ama-assn.org] The weakening of the heart's pumping ability causes Blood and fluid to back up into the lungs The buildup of fluid in the feet, ankles and legs - called edema Tiredness and[medlineplus.gov] A weak heart pumps less blood to your kidneys and causes fluid and water retention, resulting in swollen ankles, legs, and abdomen (called edema ) and weight gain.[webmd.com]

  • Venous Insufficiency

    Edema accumulates, and can cause significant leg swelling. It slows oxygen and nutrient delivery to the tissues, while damage to blood vessels triggers inflammation.[lympha-press.com] Chronic Venous insufficiency can cause varicose veins, leg edema, leg pain, chronic skin changes, and non-healing ulcers.[gasurgery.com] Elastic bandages are used initially until edema and ulcers resolve and leg size stabilizes; commercial compression stockings are then used.[msdmanuals.com]

  • Hereditary Angioedema

    Hereditary angioedema (HAE) is characterized by nonpitting, nonpruritic subcutaneous, or submucosal edema that may be accompanied by a nonpruritic serpentine erythematous[ncbi.nlm.nih.gov] Typical involvement includes the face, hands, arms, legs, genitalia, and buttocks, although the edema can localize subcutaneously at any site.[emedicine.medscape.com] […] unrelated to their menstrual cycle. 38 Symptoms are described as edema of hands, legs and face, which may be real or perceived by the patient.[doi.org]

  • Nephrotic Syndrome

    We report the case of a 23-year-old woman with a 2-week history of swelling around the eyes and both legs, and generalized body swelling.[ncbi.nlm.nih.gov] One month after oral prednisolone was started at 40 mg daily and tapered to 10 mg daily, he developed lower leg edema on both sides and marked proteinuria (10.8 g/day).[ncbi.nlm.nih.gov] The edema that is present in the legs may also be occurring in the kidney tissue itself and can interfere with the kidneys' ability to clean the blood.[healthcommunities.com]

  • Amyloidosis

    Patients usually exhibit symptoms of congestive heart failure, including: Shortness of breath Labored breathing during exercise Peripheral swelling ( edema caused by a buildup[pfizer.com] Patients may experience symptoms such as foamy urine or leg edema.[nyp.org] A 72-y-old woman presented with a 1-y history of droopy upper left eyelid, resulting in decreased visual acuity, and progressive tongue swelling, resulting in dysarthria,[ncbi.nlm.nih.gov]

  • Chronic Kidney Disease

    Potential complications may include: Fluid retention, which could lead to swelling in your arms and legs, high blood pressure, or fluid in your lungs (pulmonary edema) A sudden[mayoclinic.org] Once the kidney is severely damaged, the symptoms of CKD can include: swelling around your eyes, called periorbital edema swelling of your legs, called pedal edema fatigue[healthline.com] Edema can occur in the legs, feet, or ankles, and less often in the hands or face.[niddk.nih.gov]

  • Aortic Valve Insufficiency

    Diuretics, or water pills, can help relieve body swelling, or edema, that’s due to congestive heart failure. The swelling is not always present, however.[webmd.com] Accordingly, a thorough lung exam is required to evaluate for pulmonary edema, as is an evaluation of the legs and sacrum for signs of peripheral edema.[clinicaladvisor.com] Swelling in the legs and sometimes the rest of the body (edema). Awareness of the heartbeat ( palpitations ), especially when lying on the left side.[northshore.org]

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