Leg Pain: Possible Causes & Differential Diagnoses

Deep Vein Thrombosis
Leg Pain

Swelling of the leg Pain or tenderness which may be associated with walking or standing Erythema or discolored skin Dilated superficial veins Low grade fever with increased^[1]
Cervical Cancer
Leg Pain

Symptoms of advanced cervical cancer may include: loss of appetite, weight loss, fatigue, pelvic pain, back pain, leg pain, swollen legs, heavy vaginal bleeding, bone fractures^[2]
Torn Meniscus
Leg Pain

Diagnosis is made on the basis of the following: Patient’s history and inquiring the detail of the injury. Physical examination. The signs that are useful in diagnosing torn meniscus include McMurray test, Steinmann test, Apley test, Thessaly test, Bragard sign, Böhler sign, Payr sign, Merke sign, Childress sign and…^[3]
Phlegmon
Leg Pain
Gaucher Disease
Leg Pain

Although the diagnosis can't be made solely on physical signs, a clinical suspicion toward this condition should be made in patients where other causes have been excluded, such as lymphomas and leukemias, as well as other lysosomal storage diseases that have a similar clinical presentation. Workup starts with a…^[4]
Arterial Embolism
Intermittent Leg Claudication Leg Pain
Bone Tumor
Leg Pain

Bone malignant tumors are rarely encountered in clinical practice, as primary bone malignancies (bone sarcomas) comprise about 0.2% of all cancers. In addition to malignant, several benign tumors have been described, most common being osteochondroma, benign giant cell tumor, osteoma, and osteoid osteoma, which are…^[5]
Bacterial Arthritis
Leg Pain

Bacterial arthritis or infection of the joints and the articular tissues is encountered across all age groups. Overall, Staphylococcus aureus is the most common cause (although Neisseria gonorrhoeae is the number one cause of septic arthritis in younger adults), but streptococcal species (including S. pneumoniae, S.…^[6]
Polyarthritis
Leg Pain

Mies Richie A, Francis ML. Diagnostic approach to polyarticular joint pain. Am Fam Physician. 2003; 68(6):1151-1160. Smith JW, Chalupa P, Shabaz Hasan M. Infectious arthritis: clinical features, laboratory findings and treatment. Clin Microbiol Infect. 2006; 12(4):309-314. de Hair MJ, Lehmann KA, van de Sande MG, Maijer KI,…^[7]
Sciatica
Leg Pain

Sciatica, or sciatic neuritis, is a common condition that affects the whole or part of the sciatic nerve. Damage or compression to any one of the nerve roots causes characteristic and often progressive symptoms to appear. The sciatic nerve is the largest and thickest nerve of the body. It is formed from L4 to…^[8]

Possible Causes for Leg Pain in USA

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Further symptoms

Similar symptoms

References