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356 Possible Causes for Leg Pain, Night Sweats, Splenomegaly

  • Myeloproliferative Disease

    CML: demonstrates increased production of neutrophils and marked splenomegaly.[ncbi.nlm.nih.gov] Painful swollen joints, caused by gouty arthritis , which is in turn caused by hyperuricemia Bone pain Priapism Tinnitus Stupor due to leukostasis Left upper quadrant and[diagnose-me.com] Patients usually present with fatigue, weight loss, anemia, night sweats, and splenomegaly.[icd9data.com]

  • Hodgkin's Disease

    The presenting feature common in all cases was superficial lymphadenopathy followed by hepatomegaly in 17 (20%) cases and splenomegaly in 16 (19%).[ncbi.nlm.nih.gov] sweats and weight loss.[ncbi.nlm.nih.gov] Hodgkin's lymphoma symptoms include night sweats, enlarged lymph nodes, splenomegaly, and back pain. Treatment entails radiotherapy or chemotherapy.[medscape.org]

  • Essential Thrombocythemia

    […] essential thrombocythemia (ET) are myeloproliferative neoplasms respectively characterized by erythrocytosis and thrombocytosis; other disease features include leukocytosis, splenomegaly[ncbi.nlm.nih.gov] Resources - Hemorrhagic thrombocythemia (Essential Thrombocythemia) Call your health care provider: * If unexplained or prolonged bleeding occurs * If chest pain, leg pain[checkorphan.org] In one large internet-based survey of 304 patients with ET, 72% reported fatigue, and 40% or more reported itching, night sweats and bone pain.[healio.com]

  • B-Precursor Acute Lymphoblastic Leukemia

    64.0%) 66 (66%) 62 (%) 0.556 Bleeding 96 (48.0%) 45 (45%) 51 (51%) 0.396 Lymphadenopathy 112 (56.0%) 53 (53%) 59 (59%) 0.393 Hepatomegaly 84 (42.0%) 46 (46%) 38 (38%) 0.252 Splenomegaly[omicsonline.org] Accelerated phase of CML Children whose CML is in accelerated phase may have symptoms such as fever, night sweats, poor appetite, and weight loss.[cancer.org] […] even trigger hemophagocytic lymphohistiocytosis and macrophage activation syndrome, which are disorders of abnormal immune system activation characterized by high fever, splenomegaly[dovepress.com]

  • Brucellosis

    The most frequent admission symptoms and findings of the patients with pancytopenia were fever (75%), fatigue (50%), splenomegaly (75%), and hepatomegaly (41%).[ncbi.nlm.nih.gov] Back pain and radiating leg pain was relieved significantly in all patients after operation. No implant failures were observed in any patients.[ncbi.nlm.nih.gov] The patient described fever, night sweats, widespread muscle pain and fatigue that had been going on for the last six days.[ncbi.nlm.nih.gov]

  • Polyarthritis

    Abdominal examination - may reveal evidence of hepatomegaly and/or splenomegaly. Examine other systems as indicated by the history and clinical hypotheses.[patient.info] CASE PRESENTATION: A 19-year-old Caucasian woman presented to our hospital with fever, intense leg pain, and a transient rash.[ncbi.nlm.nih.gov] Patients suffering from inflammatory polyarthritis may additionally report fatigue, fever, night sweats, weight loss and lymphadenopathy.[symptoma.com]

  • Primary Myelofibrosis

    Abstract We report a patient with very advanced myelofibrosis and huge splenomegaly who showed a complete hematological response to low dose thalidomide with reversal of splenomegaly[ncbi.nlm.nih.gov] […] or discomfort pain in the left shoulder or upper left portion of the body unexpected bleeding bone pain, especially in the legs Diagnosis Because symptoms are similar to[medical-dictionary.thefreedictionary.com] Constitutional symptoms, such as night sweats, pruritus, weight loss and fever may be treated with Jakafi.[mpnresearchfoundation.org]

  • Sarcoidosis

    Abdomen Check for hepatomegaly and splenomegaly.[patient.info] pain, voice change and cough.[doi.org] If you have symptoms, they may include cough shortness of breath weight loss night sweats fatigue tests to diagnose sarcoidosis include chest x-rays, lung function tests,[icd9data.com]

  • Childhood Acute Lymphoblastic Leukemia

    The child redeveloped splenomegaly and fever, and then suffered an acute decompensation with hypoxemia, tachypnea, splenomegaly, and cardiac gallop.[ncbi.nlm.nih.gov] Abstract A 2 years old male child was admitted in Dhaka Shishu Hospital with one month history of fever, swelling and pain in joints of right leg.[ncbi.nlm.nih.gov] They include: Fatigue Fever Loss of appetite or weight Night sweats Many symptoms of acute lymphoblastic leukemia are the result of a shortage of normal blood cells.[webmd.com]

  • Bacterial Endocarditis

    The condition is characterized by heart murmur, prolonged fever, bacteremia, splenomegaly, and embolic phenomena.[medical-dictionary.thefreedictionary.com] : Severe chills and high fever Shortness of breath on exertion Swelling of the feet, legs and abdomen Rapid or irregular heartbeat Diagnosis: A blood test is the primary test[maxor.com] The clinical presentation is one of fever, night sweats, weight loss, and weakness, with additional symptoms due to cardiac failure or embolism.[gpnotebook.co.uk]

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