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967 Possible Causes for Leg Pain, Toe Pain, Weight Loss

  • Myeloproliferative Disease

    Some people experience gout, which usually presents as a painful inflammation of the big toe or foot.[leukaemia.org.au] Splenomegaly, hepatomegaly as well as fatigue, malaise or weight loss may appear in advanced stages.[orpha.net] Painful swollen joints, caused by gouty arthritis , which is in turn caused by hyperuricemia Bone pain Priapism Tinnitus Stupor due to leukostasis Left upper quadrant and[diagnose-me.com]

  • Fabry Disease

    A 57-year-old male with a family history and laboratory findings of Fabry disease, was consulted for severe abdominal pain, undulating pyrexia, weight loss and diarrhea.[ncbi.nlm.nih.gov] In this paper, we studied a 54 year-old female who had complaints of leg pain, palpebral edema and telangiectasis and in whom foam cells in renal biopsy as well as proteinuria[jstage.jst.go.jp] Gastrointestinal disease: this can include symptoms of diarrhoea, weight loss abdominal pain, nausea and vomiting.[patient.info]

  • Arthritis

    Psoriatic arthritis can cause a painful, sausage-like swelling of your fingers and toes.[mayoclinic.com] Even small amounts of weight loss -- 10 pounds or so -- can cut the risk of knee osteoarthritis, particularly among women, so efforts to treat and prevent obesity could help[web.archive.org] See Leg Pain and Numbness: What Might These Symptoms Mean? Because the pain runs down the leg people, even doctors sometimes, confuse it with nerve root pain.[spine-health.com]

  • Polyarthritis

    A 19-year-old Caucasian woman presented to our hospital with fever, intense leg pain, and a transient rash.[ncbi.nlm.nih.gov] The big toe is a common pain point for people with gout, though other symptoms include redness, swelling, and heat and stiffness in one or more joints.[mdmag.com] loss eventually led to the diagnosis of metastatic pancreatic adenocarcinoma.[ncbi.nlm.nih.gov]

  • Peripheral Vascular Disease

    Approximately 48 hours after the procedure, the patient developed severe, right lower leg pain.[ncbi.nlm.nih.gov] PAIN IN TOES OR FEET WHILE RESTING If you have pain in your toes or feet while resting, you may have an advancing case of PAD.[vascular.org] Treatment of Peripheral Vascular Disease (PVD)/Peripheral Arterial Disease (PAD) Lifestyle Changes - Changes such as smoking cessation, exercise and weight loss will help[uvmhealth.org]

  • Cervical Cancer

    We report a patient with a toe metastasis that first presented with pain caused by a pathological fracture.[ncbi.nlm.nih.gov] The primary presentation was general fatigue and body weight loss.[ncbi.nlm.nih.gov] Signs of advanced cervical cancer include: Weight loss Fatigue Back pain Leg pain or swelling Leakage of urine or feces from the vagina Bone fractures Next topic: What are[cancercenter.com]

  • Lipedema

    *Pain in legs and sensitivity to touch caused by lymph blockage that leads to hardening of tissues.[alignlife.com] "If my cat jumped onto my lap, it felt really bad, like stubbing a toe," recalls Crystal Willis, a 32-year-old from Glendale, California.[marieclaire.com] Weight loss can be challenging for many people who do not have this condition and there can be many reasons for this.[wholehealthllc.com]

  • Polycythemia Vera

    The fatigue continued as well as subtle symptoms creeping up; headaches, edema, leg pain, orbital pain and discoloration (dark eyes), stomach and digestive issues.[pvreporter.com] When the patient was admitted he suffered from ischemic pain, he had developed an ulcer on his big toe and he was emotionally unstable, with suicidal thoughts.[ncbi.nlm.nih.gov] Palpable splenomegaly is one of the worst offenders since it contributes to early satiety, bloating, pain, portal hypertension, weight loss, and exacerbation of cytopenia.[medpagetoday.com]

  • Hemophilia

    Symptoms may include fatigue, nausea, vomiting, muscle and joint aches, liver tenderness and enlargement and/or weight loss.[arizonahemophilia.org] […] weakness or clumsiness of the arms or legs or problems walking Double vision Convulsions or seizures[web.archive.org] Painful bleeding into the soft tissues of the arms and legs can lead to nerve damage.[genome.gov]

  • Essential Thrombocythemia

    Blood vessel disturbances or bleeding can result in: Headache Vision disturbances or silent migraines Dizziness or lightheadedness Coldness or blueness of fingers or toes[hopkinsmedicine.org] Others may have symptoms such as: skin problems such as redness, burning, or itching pain in the feet and hands a mildly enlarged spleen headache, dizziness, weight loss abnormal[medicalmarijuana.com] Resources - Hemorrhagic thrombocythemia (Essential Thrombocythemia) Call your health care provider: * If unexplained or prolonged bleeding occurs * If chest pain, leg pain[checkorphan.org]

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