Leg Ulcer: Causes & Reasons

Possible Causes for Leg Ulcer

We present the case of a 58-year-old man who presented to our wound care centre with a 7 -month history of a progressive unilateral leg ulcer. [ncbi.nlm.nih.gov]

[…] veins, "hidden varicose veins", thread veins, swollen or aching legs or venous leg ulcers. [markwhiteley.co.uk]

A venous leg ulcer (a break in the skin below the knee that has not healed within 2 weeks). [nice.org.uk]

Stasis Dermatitis

[…] for around 15% of chronic leg ulcers. [epainassist.com]

Abstract Patients suffering from stasis dermatitis and leg ulcers (192) were found to give an allergic reaction in epicutaneous tests to one or more components of topical [ncbi.nlm.nih.gov]

This abnormally increased vein pressure causes skin damage to the legs and leads to chronic leg ulcers. [epainassist.com]

Diabetic Foot Ulcer

Around one per cent of the Australian population suffers from leg ulcers (chronic venous leg ulceration). [betterhealth.vic.gov.au]

Find out how a venous leg ulcer is diagnosed What causes venous leg ulcers? [nhs.uk]

This is a chronic leg ulcer. What causes leg ulcers? The most common underlying problem causing chronic leg ulcers is disease of the veins of the leg. [circulationfoundation.org.uk]

Varicose Ulcer

Find out how a venous leg ulcer is diagnosed What causes venous leg ulcers? [nhs.uk]

leg ulcers. [nhsdirect.wales.nhs.uk]

How is a venous leg ulcer diagnosed? The appearance of a venous leg ulcer is usually fairly typical. [patient.info]

Venous Stasis Ulcer

How is a venous leg ulcer diagnosed? The appearance of a venous leg ulcer is usually fairly typical. [patient.info]

State-of-the-Art Leg Ulcer Treatment that Cures Venous Stasis Traditional treatment for venous stasis leg ulcers (when the condition is properly diagnosed), has involved invasive [veinspecialistsofarizona.com]

The treatment for non-venous ulcers is different to that of venous ulcers. The rest of this leaflet deals only with venous leg ulcers. What causes venous leg ulcers? [patient.info]

Tropical Phagedenic Ulcer

Systemic therapy for leg ulcers. Indian Dermatol Online J 2014;5:539-40 Sir, The article venous leg ulcer: Systemic therapy by B Nair [1] was very well-written. [idoj.in]

Published on Apr 19, 2016 Leg ulcers 1. LEG ULCERSLEG ULCERS Dr Y SRI HARSHA 2. WHAT IS AN ULCER??WHAT IS AN ULCER?? 3. [slideshare.net]

Leg ulcer (Venous ulcer or stasis dermatitis) Leg ulcer is caused by venous insufficiency, which leads to fluid and blood cells leaking from the veins into the skin and other [firstderm.com]

Postphlebitic Syndrome

Leg ulcers are long-term complications of DVT and will not be observable in patients presenting with acute thromboembolism. [symptoma.com]

Community leg ulcer clinics: effect on quality of life. Phlebology. 1994;9:83–6. Google Scholar 29. Hyland ME, Thomson B. [link.springer.com]

The book discusses vascular factors in the management of leg ulcers and the interrelationship of venous disorders with ischemia and other conditions. [books.google.de]

Pyoderma Gangrenosum

What Are Leg Ulcers? Leg ulcers form when skin on your leg breaks open. These breaks or sores let air and bacteria travel into your skin’s tissue. [healthcare.utah.edu]

Overview What Are Leg Ulcers? What Are Leg Ulcers? Leg ulcers form when skin on your leg breaks open. [healthcare.utah.edu]

[…] role in the refractory nature of leg ulcers for PGA patients. [jamanetwork.com]

Sickle Cell Anemia

Hyperbaric Oxygen Therapy in the Treatment of Sickle Cell Leg Ulcers. J. Hyperbaric Med 1991; 6(1):1-4. [archive.rubicon-foundation.org]

The third patient had sickle cell trait with an extensive leg ulcer that was associated with epidermoid carcinoma. [ncbi.nlm.nih.gov]

ulcers and priapism. [ncbi.nlm.nih.gov]

Hereditary Spherocytosis

However, complete clearance of the leg ulcer was not achieved until two months after a splenectomy. [ncbi.nlm.nih.gov]

Taylor (1939) reported a case of chronic leg ulcer in HS. [4] In our case both the patient's and his mother's main problem was recurrent leg ulceration, that too started at [ijdvl.com]

Less common complications include leg ulcers, extramedullary hematopoietic tumors, priapism, spinocerebellar degenerative syndromes, hypertrophic cardiomyopathy, and movement [visualdx.com]

Felty Syndrome

This is a case report of a black woman with Felty's syndrome, who had recurrent, severe leg ulcers refractive to the usual treatment. [ncbi.nlm.nih.gov]

Felty's syndrome is characterized by neutropenia, splenomegaly, and leg ulcers in patients with rheumatoid arthritis. [ncbi.nlm.nih.gov]

Features of vasculitis - leg ulcers, brown pigmentation on the legs, periungual infarcts, ischaemia of the extremities. Peripheral neuropathy. [patient.info]

Cryoglobulinemia

We describe a case of HCV-positive type I cryoglobulinemia with severe leg ulcers, not responsive to antiviral and immunosuppressive treatment. [ncbi.nlm.nih.gov]

Clinical manifestations included leg ulcers, livedo reticularis, renal failure, and peripheral neuropathy. [ncbi.nlm.nih.gov]

We describe a case of a 79-year-old woman with a non-cirrhotic hepatitis C virus infection presenting with weakness, arthralgias, purpuric rash with left leg ulcerative lesions [ncbi.nlm.nih.gov]

Klinefelter Syndrome

We present a man with refractory leg ulcers, bilateral varicosis of the lower extremities, and Buerger disease. Autoimmune work-up was negative. [ncbi.nlm.nih.gov]

A case of KFS with post acne scars and leg ulcers is presented, who responded well to testosterone replacement therapy with complete healing of the leg ulcers. [ncbi.nlm.nih.gov]

The leg ulcers in patients with Klinefelter syndrome are usually attributed to venous insufficiency. [pathopedia-india.com]

Pyruvate Kinase Deficiency

A splenectomy was performed and the leg ulcer was treated un-successfully with a pinch graft. [ncbi.nlm.nih.gov]

Adults may have chronic leg ulcers. Differential diagnosis Other causes of haemolytic anaemia. [patient.info]

The propositus, an 18-yr-old boy, suffered from recurrent crises of hemolytic anemia and leg ulcers. [ncbi.nlm.nih.gov]

Anticardiolipin Antibody Syndrome

Other features include: Splinter haemorrhage (one or more red or black streaks on a nail) Leg ulcers, both arterial and venous ulcers Superficial thrombophlebitis Blue toe [dermnetnz.org]

You may see edema, claudication, blue-toe syndrome, necrotizing purpura, and leg ulcers that may be painful. [journals.lww.com]

ulcers (6%) Amaurosis fugax (5%) 5:1 Ratio Antiphospholipid syndrome is more common in women than men. [thermofisher.com]

Buruli Ulcer

Infection leads to destruction of skin and soft tissue with large ulcers usually on the legs or arms. [web.archive.org]

Differential diagnoses of Buruli ulcer include tropical phagedenic ulcers, chronic lower leg ulcers due to arterial and venous insufficiency (often in elderly populations) [who.int]

Comparative study of two antimicrobial dressings in infected leg ulcers: a pilot study. J Wound Care. 2015, Vol. 24, 3, pp. 121-27. Stanirowski PJ et coll. [sorbact.fr]

Peripheral Vascular Disease

In nondiabetic patients, statistically significant differences in leg-ulcer healing were found between the treatment and placebo groups. [ncbi.nlm.nih.gov]

Such blockages are sometimes associated with non-healing leg wounds or ulcers, which in dire cases may threaten limb viability. [heart.ucla.edu]

If the leg is even slightly injured, ulcers may form because, without a good blood supply, proper healing can not take place. [medical-dictionary.thefreedictionary.com]

Congenital Heinz Body Hemolytic Anemia

ulcers, bilirubin gallstones Neonatal syndromes (hemoglobin Poole and hemoglobin Hasharon [γ-globin variants]) Neonatal hemolysis – jaundice, anemia Resolves with aging as [arupconsult.com]

Leg Ulcers 5. Auto-splenectomy. 6. Crisis* Splenic atrophy – (Auto-infarction) 16. The power of thought is not a compelling force. [slideshare.net]

Leg ulcers. After all of the disasters mentioned above, this seems trivial. [web2.iadfw.net]

Beta Thalassaemia Major

Untreated or poorly transfused patients show growth retardation, pallor, jaundice, poor musculature, genu valgum, leg ulcers, formation of masses due to extramedullary hematopoiesis [orpha.net]

Common symptoms include pallor, jaundice, leg ulcers, gallstones (cholelithiasis), and abnormal enlargement of the liver and spleen. [rarediseases.org]

Other symptoms include: poor growth pallor jaundice enlargement of the liver and spleen due to the breakdown of red cells containing the abnormal hemoglobin leg ulcers bone [news-medical.net]

Thromboangiitis Obliterans

587 Major Amputation of the Lower Extremity for Critical Limb Ischemia 603 Extremity Replantation or Transplantation 618 The Importance of a Multidisciplinary Approach to Leg [books.google.ro]

An abnormal Allen test [ 7, 19 ] in a young smoker presenting with leg ulcerations is highly suggestive of TAO. [ncbi.nlm.nih.gov]

Ulcers 625 Appropriate Endpoints for Chronic Limb Ischemia 629 Economic Burden of Chronic Critical Limb Ischemia 637 The LongTerm Care of Patients with Critical Limb Ischemia [books.google.ro]

Antiphospholipid Syndrome

CASE SUMMARY: A 50-year-old woman with the antiphospholipid syndrome, manifesting clinically with recurrent pyoderma gangrenosum-like leg ulcers, was treated with apixaban [ncbi.nlm.nih.gov]

RESULTS: Clinical manifestations included leg ulcers, livedo reticularis, renal failure, and peripheral neuropathy. [ncbi.nlm.nih.gov]

Other features include: Splinter haemorrhage (one or more red or black streaks on a nail) Leg ulcers, both arterial and venous ulcers Superficial thrombophlebitis Blue toe [dermnetnz.org]

Venous Thrombosis

Ulcers [columbiasurgery.org]

This condition is characterized by pooling of blood, chronic leg swelling, increased pressure, increased pigmentation or discoloration of the skin, and leg ulcers known as [my.clevelandclinic.org]

Mesenteric Arterial Occlusive Disease Sclerotherapy for Vein Disease Spider Veins Thoracic Outlet Syndrome (Vascular) Thrombophlebitis Varicose Veins Vein Disease Overview Venous Leg [columbiasurgery.org]

Polyarteritis Nodosa

Clinical manifestation of cutaneous PAN includes the presence of nodules in the lower legs and ulceration is a frequent complication. [revistasocolderma.org]

In June 2001, she was aware of edema and pain in both lower legs. At the same time, indurated erythemas and ulcers are seen on her lower legs. [ci.nii.ac.jp]

Polyarteritis nodosa with extended ulcers on the lower part of the leg before low-dose methotrexate treatment. Figure 2. [doi.org]

Rheumatoid Arthritis

In this paper, we present a Japanese woman with RA, who suffered from bilateral leg ulcers secondary to DC. [ncbi.nlm.nih.gov]

Felty's syndrome (enlarged spleen and low white cell count); can present with an infection or leg ulcer. Amyloidosis (rare). Anaemia. [patient.info]

Although the ulcers on her left leg were gradually epithelialized after one year, they may easily recur due to whitish abnormal underlying tissues, and a large ulcer remains [ncbi.nlm.nih.gov]

Vasculitis

Typical clinical features include weight loss, fever, numbness or weakness due to damaged nerves and leg ulcers, but it is important to recognise that leg ulcers occur in [nras.org.uk]

You may have: pain skin discoloration lesions, which are usually seen on the legs ulcers on the skin or genitals, or in the mouth In some cases, the condition may be limited [healthline.com]

Arteriosclerosis

[…] of right leg with ulceration of toe heel I70.434 ICD-10-CM Diagnosis Code I70.434 Atherosclerosis of autologous vein bypass graft(s) of the right leg with ulceration of heel [icd10data.com]

The management of the chronically ischemic leg with ulcer formation that is not suitable for either surgical or interventional treatment is still a matter of controversy. [ncbi.nlm.nih.gov]

The patient had renal dysfunction and nephrotic syndrome with progressive skin ulcers in the left leg. The patient was diagnosed as ASO with LCDD. [ncbi.nlm.nih.gov]

Dracunculiasis

Its victims develop large ulcers, usually in the lower leg. [who.int]

Pelt quality is not impaired by the worm's presence for the ulcerations occur only on the legs. [web.archive.org]

A X-ray of left leg showed no evidence of osteomyelitis however, it revealed a linear calcification ending in the ulcer. [ncbi.nlm.nih.gov]

Squamous Cell Carcinoma of the Skin

legs Size varies from a few millimetres to several centimetres in diameter. [dermnetnz.org]

Non-sun-exposed sites Sites of chronic scarring Non-healed leg ulcers Anus Early squamous cell carcinoma appears as a small, pink to red, scaly spot. [skinsight.com]

[…] occupation or recreation Smoking Fair skin, blue eyes and blond or red hair Previous cutaneous injury, thermal burn, disease (eg cutaneous lupus, epidermolysis bullosa, leg [dermnetnz.org]

Diabetes Mellitus

See Diabetic Foot, Leg Ulcers, Painful Foot. Frequent, recurrent and persistent infections. [patient.info]

See Diabetic Foot, Leg Ulcers and Painful Foot. Frequent, recurrent and persistent infections. [patient.info]

Femoral Artery Occlusion

We present a case of progressive right common femoral artery stenosis resulting in resting leg ischemia and ulceration that was temporally related to multiple ipsilateral [ncbi.nlm.nih.gov]

"Doppler assessment and ABPI: Interpretation in the management of leg ulceration". Worldwide Wounds. [en.wikipedia.org]

Foot ulcers may develop. Leg muscles usually shrink (atrophy). A large blockage may cause gangrene. [msdmanuals.com]