Leg Ulcer: Causes & Reasons

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Possible Causes for Leg Ulcer

Diabetes Mellitus

See Diabetic Foot, Leg Ulcers, Painful Foot. Frequent, recurrent and persistent infections. [patient.info]

See Diabetic Foot, Leg Ulcers and Painful Foot. Frequent, recurrent and persistent infections. [patient.info]

Varicose Veins

We present the case of a 58-year-old man who presented to our wound care centre with a 7 -month history of a progressive unilateral leg ulcer. [ncbi.nlm.nih.gov]

A venous leg ulcer (a break in the skin below the knee that has not healed within 2 weeks). [nice.org.uk]

ulcer (a break in the skin below the knee that has not healed within 2 weeks); or a healed venous leg ulcer. [bjgp.org]

Arteriosclerosis

[…] of right leg with ulceration of toe heel I70.434 ICD-10-CM Diagnosis Code I70.434 Atherosclerosis of autologous vein bypass graft(s) of the right leg with ulceration of heel [icd10data.com]

The management of the chronically ischemic leg with ulcer formation that is not suitable for either surgical or interventional treatment is still a matter of controversy. [ncbi.nlm.nih.gov]

The patient had renal dysfunction and nephrotic syndrome with progressive skin ulcers in the left leg. The patient was diagnosed as ASO with LCDD. [ncbi.nlm.nih.gov]

Klinefelter Syndrome

We present a man with refractory leg ulcers, bilateral varicosis of the lower extremities, and Buerger disease. Autoimmune work-up was negative. [ncbi.nlm.nih.gov]

A case of KFS with post acne scars and leg ulcers is presented, who responded well to testosterone replacement therapy with complete healing of the leg ulcers. [ncbi.nlm.nih.gov]

The leg ulcers in patients with Klinefelter syndrome are usually attributed to venous insufficiency. [pathopedia-india.com]

Malignant Neoplasm of the Skin

[…] for SCC in people of color include scars from thermal and chemical burns ( Copcu et al, 2003 ), chronic leg ulcers (King et al, 2008), and previous sites of radiation. [ncbi.nlm.nih.gov]

Superficial BCC is typically found on the chest, back, arms, and legs. Learn More Close Ulcerated BCC Over time, the top layer skin may begin to break down. [skincancer.net]

Tumors of the scalp, ala nasi, nasolabial fold, tragus, postauricular sulcus, free eyelid margin, upper lip vermillion border, and lower legs. Tumors near nerves. [cancer.gov]

Squamous Cell Carcinoma of the Skin

legs Size varies from a few millimetres to several centimetres in diameter. [dermnetnz.org]

Non-sun-exposed sites Sites of chronic scarring Non-healed leg ulcers Anus Early squamous cell carcinoma appears as a small, pink to red, scaly spot. [skinsight.com]

[…] occupation or recreation Smoking Fair skin, blue eyes and blond or red hair Previous cutaneous injury, thermal burn, disease (eg cutaneous lupus, epidermolysis bullosa, leg [dermnetnz.org]

Stasis Dermatitis

[…] for around 15% of chronic leg ulcers. [epainassist.com]

Abstract Patients suffering from stasis dermatitis and leg ulcers (192) were found to give an allergic reaction in epicutaneous tests to one or more components of topical [ncbi.nlm.nih.gov]

This abnormally increased vein pressure causes skin damage to the legs and leads to chronic leg ulcers. [epainassist.com]

Hereditary Spherocytosis

However, complete clearance of the leg ulcer was not achieved until two months after a splenectomy. [ncbi.nlm.nih.gov]

Taylor (1939) reported a case of chronic leg ulcer in HS. [4] In our case both the patient's and his mother's main problem was recurrent leg ulceration, that too started at [ijdvl.com]

Less common complications include leg ulcers, extramedullary hematopoietic tumors, priapism, spinocerebellar degenerative syndromes, hypertrophic cardiomyopathy, and movement [visualdx.com]

Ischemic Ulcer

[…] cause of leg ulcers. [journals.lww.com]

The majority of leg ulcers (75%) were due to vascular etiologies. 2 Although venous leg ulcers are the most common etiology for leg ulcers, the differential diagnoses are [journals.lww.com]

The majority of leg ulcers (75%) were due to vascular etiologies.2 Although venous leg ulcers are the most common etiology for leg ulcers, the differential diagnoses are vast [journals.lww.com]

Rheumatoid Arthritis

In this paper, we present a Japanese woman with RA, who suffered from bilateral leg ulcers secondary to DC. [ncbi.nlm.nih.gov]

Felty's syndrome (enlarged spleen and low white cell count); can present with an infection or leg ulcer. Amyloidosis (rare). Anaemia. [patient.info]

Although the ulcers on her left leg were gradually epithelialized after one year, they may easily recur due to whitish abnormal underlying tissues, and a large ulcer remains [ncbi.nlm.nih.gov]

Diabetic Foot Ulcer

Causes, investigation and treatment of leg ulceration. Br J Dermatol. 2003, 148: 388-401. Gonsalves CF. Venous leg ulcers. [clevelandclinicmeded.com]

Around one per cent of the Australian population suffers from leg ulcers (chronic venous leg ulceration). [betterhealth.vic.gov.au]

Find out how a venous leg ulcer is diagnosed What causes venous leg ulcers? [nhs.uk]

Varicose Ulcer

Find out how a venous leg ulcer is diagnosed What causes venous leg ulcers? [nhs.uk]

leg ulcers. [nhsdirect.wales.nhs.uk]

How is a venous leg ulcer diagnosed? The appearance of a venous leg ulcer is usually fairly typical. [patient.info]

Venous Stasis Ulcer

Symptoms of venous stasis leg ulcers are similar to those of varicose veins, and can include swollen legs, itchy skin, or painful lesions on the skin. [goldmanveininstitute.com]

How is a venous leg ulcer diagnosed? The appearance of a venous leg ulcer is usually fairly typical. [patient.info]

Symptoms of Venous Stasis Leg Ulcers Early signs of venous ulcers include darkened or discolored skin around the ankle, or skin that feels leathery or waxy to the touch. [goldmanveininstitute.com]

Vasculitis

Typical clinical features include weight loss, fever, numbness or weakness due to damaged nerves and leg ulcers, but it is important to recognise that leg ulcers occur in [nras.org.uk]

You may have: pain skin discoloration lesions, which are usually seen on the legs ulcers on the skin or genitals, or in the mouth In some cases, the condition may be limited [healthline.com]

Malignant Melanoma of the Skin

In males the back was the most frequently involved, while in females the lesions occurred preferentially in the legs. [ncbi.nlm.nih.gov]

The ulceration was present in 22.3% of cases and prevailed in thick melanomas as well in nodular subtype. Most patients present at stage IA. [ncbi.nlm.nih.gov]

Tropical Phagedenic Ulcer

Systemic therapy for leg ulcers. Indian Dermatol Online J 2014;5:539-40 Sir, The article venous leg ulcer: Systemic therapy by B Nair [1] was very well-written. [idoj.in]

Published on Apr 19, 2016 Leg ulcers 1. LEG ULCERSLEG ULCERS Dr Y SRI HARSHA 2. WHAT IS AN ULCER??WHAT IS AN ULCER?? 3. [slideshare.net]

It usually remains for five to seven days and heals within two weeks with no scarring. chronic leg ulcer ulceration of the lower leg caused by peripheral vascular disease [medical-dictionary.thefreedictionary.com]

Peripheral Vascular Disease

In nondiabetic patients, statistically significant differences in leg-ulcer healing were found between the treatment and placebo groups. [ncbi.nlm.nih.gov]

Such blockages are sometimes associated with non-healing leg wounds or ulcers, which in dire cases may threaten limb viability. [heart.ucla.edu]

If the leg is even slightly injured, ulcers may form because, without a good blood supply, proper healing can not take place. [medical-dictionary.thefreedictionary.com]

Osteomyelitis

[…] various sites), bacteraemia, bronchitis, bursitis, cellulitis, cholecystitis, diarrhoea, diverticulitis, endocarditis (suspected), gastroenteritis, hepatitis B, herpes zoster, leg [lt.glosbe.com]

Sickle cell disease and leg ulcers. Adv Skin Wound Care 2012;25(9):420-8. 20. Weisman J, Darbari D, Diab Y. [journals.lww.com]

Sickle cell disease and leg ulcers. Adv Skin Wound Care 2012;25(9):420–8. 20. Weisman J, Darbari D, Diab Y. [journals.lww.com]

Femoral Artery Occlusion

We present a case of progressive right common femoral artery stenosis resulting in resting leg ischemia and ulceration that was temporally related to multiple ipsilateral [ncbi.nlm.nih.gov]

"Doppler assessment and ABPI: Interpretation in the management of leg ulceration". Worldwide Wounds. [en.wikipedia.org]

Other symptoms include numbness or weakness in the legs, aching pain in the feet or toes while at rest, nonhealing ulcers on the leg or foot, cold legs or feet, and skin color [marmur.com]

Postphlebitic Syndrome

Community leg ulcer clinics: effect on quality of life. Phlebology. 1994;9:83–6. Google Scholar 29. Hyland ME, Thomson B. [link.springer.com]

The book discusses vascular factors in the management of leg ulcers and the interrelationship of venous disorders with ischemia and other conditions. [books.google.de]

Patients treated in nurse-led leg ulcer clinics experienced better QOL. 13 Patient & family education Education should focus on life-long use of ECS, leg elevation, smoking [now.aapmr.org]

Syphilis

Leg ulcers caused by yaws and endemic syphilis. Clin. Dermatol. 8 :166–174. 10.1016/0738-081X(90)90055-6 [ PubMed ] [ CrossRef ] [ Google Scholar ] 28. Powell A. 1923. [ncbi.nlm.nih.gov]

When you have a syphilis ulcer, the nearby glands (lymph nodes) in your groin may swell. These feel like small lumps at the top of your legs in the groin crease. [patient.info]

For example: You may have more than one ulcer. The ulcer may be painful. Pus may come from an ulcer. [patient.info]

Skin Ulcer

Venous leg ulcers Approximately 70 per cent of all leg ulcers are venous ulcers. A leg with venous problems has a very characteristic appearance. The leg is swollen. [netdoctor.co.uk]

[…] age of 80 will develop venous leg ulcers. [newatlas.com]

[…] bed sores; and leg ulcers caused by high blood pressure in the veins of the legs. [dailymail.co.uk]

Pyoderma Gangrenosum

What Are Leg Ulcers? Leg ulcers form when skin on your leg breaks open. These breaks or sores let air and bacteria travel into your skin’s tissue. [healthcare.utah.edu]

Overview What Are Leg Ulcers? What Are Leg Ulcers? Leg ulcers form when skin on your leg breaks open. [healthcare.utah.edu]

Her methotrexate was held off when she developed severe pneumonia and she then received a trial of intravenous immunoglobulins (IVIG) for her recurrent leg ulcers. [ncbi.nlm.nih.gov]

Syringomyelia

Painless ulcers on the hands. Extension of the syrinx into the lumbar region and involvement of the legs. [patient.info]

Sickle Cell Anemia

Hyperbaric Oxygen Therapy in the Treatment of Sickle Cell Leg Ulcers. J. Hyperbaric Med 1991; 6(1):1-4. [archive.rubicon-foundation.org]

The third patient had sickle cell trait with an extensive leg ulcer that was associated with epidermoid carcinoma. [ncbi.nlm.nih.gov]

ulcers and priapism. [ncbi.nlm.nih.gov]

Diabetic Neuropathy

You also can do a lot to prevent leg ulcers and amputations. [hormone.org]

Complications of Disease Peripheral neuropathy can lead to foot ulcers and leg amputations. [emedicine.medscape.com]

Ulcers, infections, deformities, and bone and joint pain in the feet. You can monitor these symptoms by: Checking your feet and legs daily. Moisturizing your feet. [wwmedgroup.com]

Venous Thrombosis

Ulcers [columbiasurgery.org]

[…] pain, swelling, venous stasis, and leg ulcers. [mja.com.au]

This condition is characterized by pooling of blood, chronic leg swelling, increased pressure, increased pigmentation or discoloration of the skin, and leg ulcers known as [my.clevelandclinic.org]

Diabetic Ulcer

Leg ulcers (venous stasis ulcers, arterial ulcers, diabetic neuropathic ulcers, pressure ulcers) Are You Confident of the Diagnosis? [clinicaladvisor.com]

Causes, investigation and treatment of leg ulceration. Br J Dermatol. 2003, 148: 388-401. Gonsalves CF. Venous leg ulcers. [clevelandclinicmeded.com]

Find out how a venous leg ulcer is diagnosed What causes venous leg ulcers? [nhs.uk]

Tuberculosis

(mostly women) that may ulcerate and scar. [dermnetnz.org]

Skin - TB can cause certain rashes, including erythema nodosum - a red, lumpy rash on the legs - or lupus vulgaris which gives lumps or ulcers. [patient.info]

[…] in good health with no identifiable focus of active TB in skin or elsewhere Erythema induratum (Bazin disease) presents as recurring nodules or lumps on the back of the legs [dermnetnz.org]

Bullous Pemphigoid

Siddiqui MA, Zaman MN (1995) Recurrent and chronic leg ulcers secondary to furosemide-induced bullous pemphigoid. J Am Geriatr Soc 43:1183-1184. [omicsonline.org]

These are most commonly seen on the: Arms Legs Abdomen Groin Mouth The blisters may break open and become an open sore or ulcer. [my.clevelandclinic.org]