1,726 Possible Causes for Leigh's Disease

  • Leigh's Disease

    Leigh syndrome may also be referred to as: Leigh’s disease classical Leigh syndrome necrotising encephalomyelopathy of Leigh’s syndrome subacute necrotising encephalopathy[medic8.com] Recently mutations in RANBP2, encoding another nuclear pore component, have been linked to infection-triggered familial acute necrotizing encephalopathy .[flipper.diff.org] Leigh’s Disease Leigh’s Disease is a rare inherited disease that effects the central nervous system.[slideshare.net]

  • Nystagmus

    In Meniere's Disease , vestibular imbalance type nystagmus is typically seen during an acute attack.[tchain.com] Leigh, R.J., Rushton, D.N., Thurston, S.E., et al.: Effects of retinal image stabilization in acquired nystagmus due to neurologic disease, Neurology 38:122-127, 1988.[webeye.ophth.uiowa.edu] What diseases cause DBN ?[dizziness-and-balance.com]

  • Cerebellar Disease

    Nutritional: Thiamine deficiency - Wernicke's encephalopathy (triad of acute confusion, ataxia and ophthalmoplegia); requires urgent thiamine treatment.[patient.info] Viral: acute infections (eg, varicella); chronic infections - eg, human immunodeficiency virus (HIV); post-viral syndromes (eg, post-infective cerebellar syndrome in childhood[patient.info] Inherited metabolic disorders - eg, Leigh's disease and the mitochondrial disorders Congenital: Developmental anomalies - eg, cerebellar hypoplasia, Dandy-Walker syndrome[patient.info]

  • Extrapyramidal Disorder
  • Optic Atrophy
  • Niemann-Pick Disease

    "Leigh's Disease."[rarediseases.about.com] Sources: " NINDS Leigh's Disease Information Page ."[rarediseases.about.com] A genetic disorder that causes Leigh's disease can be inherited in three different ways.[rarediseases.about.com]

  • Cerebellar Ataxia - Neuropathy - Vestibular Areflexia Syndrome

    This new edition of Leigh and Zee's Neurology of Eye Movements is available as an enhanced edition for the first time.[books.google.com] By placing links to figures, tables, boxes, and videos, a synthesis of basic research and clinical findings is provided, that may shed new light on disease processes and provide[books.google.com]

  • Endocrine Dysfunction

    Clinical presentation of mitochondrial disorders in childhood .[nature.com] Recessive twinkle mutations cause severe epileptic encephalopathy .[nature.com] V116* mutation in C12orf65 results in Leigh syndrome .[nature.com]

  • Canavan Disease

    Spongy degeneration of the brain can be observed in Leigh syndrome and glycine encephalopathy (see these terms) or other mitochondrial disorders and viral infections.[orpha.net] Differential diagnosis Differential diagnosis includes other neurodegenerative disorders such as Alexander disease, Tay-Sachs disease, metachromatic leukodystrophy, and glutaric[orpha.net] Genetic counseling CD is an autosomal recessively transmitted disease, recurrence risk is 25%.[orpha.net]

  • Graves Disease

    Heino, German folk singer, whose dark sunglasses (worn to hide his symptoms) became part of his trademark look Barbara Leigh, an American former actress and fashion model,[en.wikipedia.org] Less commonly, it has been known as Parry's disease, Begbie's disease, Flajani's disease, Flajani–Basedow syndrome, and Marsh's disease.[en.wikipedia.org] Graves' disease, also known as toxic diffuse goiter, is an autoimmune disease that affects the thyroid.[en.wikipedia.org]

Further symptoms