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61 Possible Causes for Lepromatous Leprosy, Saddle Nose

  • Leprosy

    Facial deformation as a sequela of leprosy is caused not only by a saddle nose but also by regression of the maxilla, as well documented in paleopathological observations[ncbi.nlm.nih.gov] Histoid leprosy is a rare manifestation of lepromatous leprosy, first described by Wade in 1960.[ncbi.nlm.nih.gov] […] oedema mixed peripheral neuropathy (often with resultant injuries) /- hypoesthesia/paresthesia /- neuralgia peripheral nerve thickening, which may be palpable corneal ulcers saddle-nose[radiopaedia.org]

  • Relapsing Polychondritis

    Since a saddle nose deformity, malacia of the auricles and sensorineural deafness were also observed, relapsing polychondritis was diagnosed.[ncbi.nlm.nih.gov] Leprosy (37 %) Subcutaneous Granuloma Annulare (37 %) ( Deep Granuloma Annulare, Pseudorheumatoid Nodule,) Nummular Dermatitis (37 %) ( Discoid Eczema, Microbial Eczema,[gulfdoctor.net] Months later she developed saddle nose deformity and hoarseness of voice. CT revealed tracheal/bronchial wall thickening and luminal narrowing.[ncbi.nlm.nih.gov]

  • Mucocutaneous Leishmaniasis

    Diffuse cutaneous leishmaniasis and lepromatous leprosy represent the anergic end of the spectrum, whereas mucocutaneous leishmaniasis and tuberculoid leprosy are associated[ncbi.nlm.nih.gov] Lepromatous leprosy and diffuse cutaneous leishmaniasis are regularly confused, particularly when no skin smears for acid-fast bacillus or Leishman-Donovan bodies are performed[ncbi.nlm.nih.gov] He had been treated for borderline lepromatous (BL) leprosy 25 years earlier. Differential diagnoses of MCL, lupus vulgaris, and subcutaneous mycosis were considered.[ncbi.nlm.nih.gov]

  • Mycobacterium Leprae

    : Infiltration of the nasopharyngeal mucosa may cause destruction of the nasal cartilage and sinking in of the nose, termed a "Saddle-nose Deformity" Peripheral Nerves: Peripheral[pathwaymedicine.org] We have described a case of a patient with an intriguing association of mucocutaneous leishmaniasis with lepromatous leprosy, two opposite polar forms of these spectral diseases[ncbi.nlm.nih.gov] To describe a 62-year-old man with chronic sun exposure and exposure to armadillos who subsequently developed lepromatous leprosy, to discuss the cutaneous malignancies that[ncbi.nlm.nih.gov]

  • Atrophic Rhinitis

    Correction of a saddle nose deformity due to atrophic rhinitis is a formidable task.[ncbi.nlm.nih.gov] Rhino-sinus mucosal involvement is well documented in untreated lepromatous leprosy, but less understood in ex-leprosy patients (i.e. leprosy patients who have been treated[ncbi.nlm.nih.gov] The nose may show a saddle-nose deformity.[en.wikipedia.org]

  • Necrotizing Vasculitis

    Most common cause of saddle nose deformity in USA (nose flattened due to destruction of nasal septum by granulomatous inflammation).[en.wikipedia.org] We report a case of cutaneous vasculitis due to a type II leprosy reaction, secondary to lepromatous leprosy.[ijams.kibanresearchpublications.com] On physical exam you note a saddle nose deformity. Laboratory results show an elevated level of cytoplasmic antineutrophil cytoplasmic antibody.[medbullets.com]

  • Lepromatous Leprosy

    She presented with multiple erythematous plaques on trunk, face and extremities, saddle nose deformity, alopecia, articular deformities of the feet and peroneal neuropathy[ncbi.nlm.nih.gov] We present a patient with long-standing lepromatous leprosy who exhibits many of these sequelae.[ncbi.nlm.nih.gov] Nasal infiltration can cause a saddle-nose deformity and impaired olfaction. Hoarseness ("leprous huskiness") and stridor are a result of laryngeal involvement.[humpath.com]

  • Hepatosplenomegaly

    Signs of late disease include Hutchinson teeth, saddle nose, saber shins, hearing impairment, hydrocephalus, and mental retardation.[aafp.org] Such observations have been reported previously in leishmaniasis, 9 lepromatous leprosy, and tuberculosis.[pmj.bmj.com]

  • Chronic Granulomatous Rhinitis

    Later, the septum is destroyed then Bridge of the nose collapses causing a saddle nose deformity. 2. Congenital It occurs in two forms: early and late form . Diagnosis..[prezi.com] Leprosy • 2 distinct polar forms of disease w spectrum in between – Tuberculoid Leprosy: • Strong host resistance • Non-infective • Localized – Lepromatous Leprosy • Poor[slideshare.net] Granulomatosis with polyangiitis patients often develop septal perforation, which can lead to the external nasal deformity known as saddle-nose deformity.[my.clevelandclinic.org]

  • Pulmonary Syphilis

    Occurs in the untreated infant regardless of early sx’s; results from chronic inflammation of the bone, teeth, and CNS HEENT: Saddle nose frontal bossing (“olympian brow”)[johnsarm.net] […] cell carcinoma in situ) Dermatophytosis Lichen planus Parapsoriasis Pityriasis rosea Psoriasis Tinea versicolor Systemic diseases Cutaneous leishmaniasis Lepromatous leprosy[aafp.org] Untreated early syphilis infections results in a high risk of poor pregnancy outcomes, including saddle nose , lower extremity abnormalities, miscarriages , premature births[en.wikipedia.org]

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