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5,620 Possible Causes for Lethargy, Muscle Hypotonia, UDP-GlcNAc Decreased

  • Hyponatremia

    Thirteen months later, he was hospitalized for lethargy and hyponatremia of 108 mEq/L, with an antidiuretic hormone level of 2.5 pg/mL, which suggested syndrome of inappropriate[ncbi.nlm.nih.gov] Motor delays and waddling gait have been attributed to muscle hypotonia. In severe cases, impaired hearing can develop over time.[biodonsys.com] A 69-year-old previously well Sinhalese man presented with lethargy, loss of appetite, vomiting, and altered behavior of 1 week's duration.[ncbi.nlm.nih.gov]

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  • Benzodiazepine Overdose

    Lethargy, slurred speech, ataxia, coma, and respiratory arrest may occur.[mhmedical.com] (lack of muscle tone) Blurry vision Difficulty breathing or depressed breathing Stupor or unresponsiveness Hallucinations Hypotension (lowered blood pressure) Coma Death[americanaddictioncenters.org] The most prevalent symptoms were ataxia (87%), lethargy (57%), coma (Glasgow coma score 15, 35%; Reed coma score 0, 22%), and respiratory depression (9%).[doi.org]

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  • Leigh's Disease

    A 7-month-old boy presented clinically with vomiting, lethargy, respiratory difficulty, deteriorated consciousness, and hypotonia.[ncbi.nlm.nih.gov] An 11-month-old boy with muscle hypotonia and neurologic deteriorations had lactic acidosis, pyruvic acidemia and alaninemia due to deficiency of the pyruvate dehydrogenase[ncbi.nlm.nih.gov] Clinical findings included irregular breathing, lethargy, and inability to feed.[ajnr.org]

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  • Short Chain Acyl CoA Dehydrogenase Deficiency

    Signs and symptoms of SCAD deficiency may appear during infancy or early childhood and can include vomiting, low blood sugar (hypoglycemia), a lack of energy (lethargy), poor[ghr.nlm.nih.gov] Of those reported cases, hypoglycemia, developmental delay, and muscle hypotonia are the most common indicated features.[mayomedicallaboratories.com] Genetic defect of SCAD was documented to cause clinical symptoms such as progressive psychomotor retardation, muscle hypotonia, and myopathy in early reports.[ncbi.nlm.nih.gov]

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  • Hypokalemia

    Patients with hypertension who frequently complain of unrefreshed sleep, daytime sleepiness, impaired concentration, fatigue, and lethargy commonly suffer from hypokalemia[empr.com] […] manifestations: -Hypotonia and muscle weakness -Respiratory depression -Muscle cramps -Constipation and/or ileus -Rhabdomyolysis and myoglobinuria In hyperkalemia, the resting[clinicaladvisor.com] […] due to weakness of accessory muscle movement to breath) Confusion, weak Flaccid paralysis Decrease deep tendon reflexes Decreased bowel sounds Easy way to Remember 7 L’s Lethargy[registerednursern.com]

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  • Propionic Acidemia

    The condition causes lethargy and striatal degeneration with motor impairment in humans. How propionate exerts its toxic effect is unclear.[ncbi.nlm.nih.gov] Clinical presentation was with acute aphasia, generalized hypotonia, and muscle weakness.[ncbi.nlm.nih.gov] Symptoms may include sleeping longer or more than usual, tiredness, vomiting, poor appetite, and weak muscle tone (hypotonia).[diseaseinfosearch.org]

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  • Methylmalonic Acidemia

    A 14 month-old boy presented with an acute generalized dystonia and lethargy preceded by fever, vomiting and lethargy at the age of 13 months.[ncbi.nlm.nih.gov] 8), muscle hypotonia (n 8), recurrent vomiting (n 4), tremor (n 2), ataxia (n 2), and abnormal posture (n 1).The onset age of seizure ranged from 8 days to 11 years.[ncbi.nlm.nih.gov] She had clinical signs of diabetic ketoacidosis such as dehydration, deep sighing respiration, smell of ketones, lethargy, and vomiting.[ncbi.nlm.nih.gov]

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  • Hypercalcemia

    We report a case of a 39-year-old female with active systemic lupus erythematosus who complained of lethargy and weakness with a moderate renal impairment.[ncbi.nlm.nih.gov] In this paper, we present a 66-year-old male kidney transplant recipient, who was admitted to our clinic with symptoms of fever, nausea, vomiting and lethargy.[ncbi.nlm.nih.gov] Although irritability and lethargy were commonly reported, no mortality or acute life-threatening events were associated with hypercalcemia and the only statistically associated[ncbi.nlm.nih.gov]

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  • Carbamoyl Phosphate Synthetase Deficiency

    Presentation History In homozygous neonates, early-onset lethargy and, in some cases, seizures are often the first signs of abnormality.[emedicine.medscape.com] […] tone (hypotonia).[rarediseases.org] (OMIM:237300) of the urea cycle, which is chemically characterised by hyperammonaemia and clinically characterised by protein intolerance, intermittent ataxia, seizures, lethargy[medical-dictionary.thefreedictionary.com]

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  • Cannabis Abuse

    […] motivation Anxiety and depression Paranoia Psychosis – hearing voices, hallucinating Physical signs your teenager may be using drugs or alcohol Bloodshot eyes Tiredness and lethargy[clinical-partners.co.uk] Amnesia, balance disorder, disturbance in attention, dysarthria, dysgeusia, lethargy, memory impairment somnolence. Blurred vision. Vertigo.[patient.info]

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