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1,243 Possible Causes for Lethargy, Somnolence

  • Appendicitis

    In the early stage of appendicitis, infants may primarily demonstrate lethargy, irritability, and loss of appetite.[] Observe the child for signs of fatigue or somnolence. Then gently palpate away from the area of pain. Percuss the abdomen.[]

  • Meningitis

    All patients had insidious onset and slow progression of behavioral and cognitive dysfunction accompanied by daytime somnolence and headache.[] However, in younger children, the signs may be far less specific and may include lethargy, irritability, and poor feeding.[] Lethargy or extreme irritability in infants.[]

  • Malignant Neoplasm

    Symptoms depend upon the location and size of the tumour and can include headache, seizures, vomiting, somnolence or spinal cord compression.[] […] metastasis Abdominal pain and jaundice due to liver metastasis Persistent coughing and chest pain due to lung metastasis Unintentional weight loss Persistent fatigue and lethargy[]

  • Ornithine Transcarbamylase Deficiency

    A 22-year-old woman with a negative urine drug screen and somnolence rapidly reversed by intravenous flumazenil was found to have elevated ammonia levels and punctate calcifications[] Ornithine transcarbamylase deficiency causes vomiting, lethargy, hyperventilation, and even death, mainly in the neonatal period.[] The patient had suffered episodes of hyperammonemic encephalopathy ranging from lethargy to coma, treated by hemodialysis twice before LDLT, and her intelligence quotient[]

  • Hypercapnia

    A 38-year-old patient with effort dyspnea, somnolence, cianosis and cor pulmonale is presented.[] Treatment with nocturnal O2 during a 2-yr period was associated with stable cardiovascular function but severe morning headaches and lethargy, presumably related to nightly[] These include Altered mental status (agitation, somnolence) Peripheral or central cyanosis or decreased oxygen saturation on pulse oximetry Manifestations of a "stress response[]

  • Hydrocephalus

    Symptoms can include vomiting, lethargy, headache, enlarged head or even seizures. There is no cure, but treatment may provide long-term relief.[] […] healthy male patient, except for a history of two previous surgeries for ulnar nerve entrapment and progressive left upper extremity weakness, presented with acute onset somnolence[] Manifestations can include enlarged head, bulging fontanelle, irritability, lethargy, vomiting, and seizures.[]

  • Myxedema

    Usually somnolence and lethargy have been present for months. Lethargy may develop via stupor into a comatose state.[] These symptoms include: Fatigue Lethargy Mental impairment Depression Cold intolerance Hoarseness Dry skin Weight gain Myxedema can be treated by managing the underlying cause[] Friends, relatives and acquaintances might have noted increasing lethargy, complaints of cold intolerance, and changes in the voice.[]

  • Hypoxia

    Signs: Rapid Breathing Cyanosis Poor Coordination Lethargy/Lassitude Executing Poor Judgment Symptoms: Air Hunger Dizziness Headache Mental and Muscle Fatigue Nausea Hot and[] Subjective symptoms may include fatigue, lassitude (state of exhaustion), somnolence (drowsiness, sleepiness), dizziness, headache, breathlessness, and euphoria.[] The symptoms in pediatric patients can be similar to the above and may include the following: Lethargy Irritableness Anxiousness Inattentiveness Sitting up and leaning forward[]

  • Carbamoyl Phosphate Synthetase Deficiency

    Children may become lethargic, somnolent and fall into coma. Seizures are common.[] Presentation History In homozygous neonates, early-onset lethargy and, in some cases, seizures are often the first signs of abnormality.[] , which depletes α-ketoglutarate - inhibits TCA cycle limit protein in diet acquired (liver dz) or hereditary (urea cycle enzyme deficiency) tremor, slurring of speech, somnolence[]

  • Hepatic Encephalopathy

    Hepatic encephalopathy typically presents with confusion, lethargy, and sometimes dramatic changes in behavior and motor skills.[] […] addition Grade 2 Lethargy or apathy Minimal disorientation for time or place Subtle personality change Inappropriate behavior Impaired performance of subtraction Grade 3 Somnolence[] Grade 3 : somnolent but rousable, unable to perform mental tasks, disorientation to time and place, marked confusion, amnesia, occasional fits of rage, speech is present but[]

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