Create issue ticket

62 Possible Causes for Lethargy Associated with Hypoglycemia, Subsarcolemmal Accumulation of Normal Mitochondria

  • Carnitine Transporter Deficiency

    […] and intermyofibrillar accumulation of mitochondria in muscles ( mitochondria stain red).[amboss.com] Laboratory studies Normal CK Elevated lactate and alanine in serum, urine and/or CSF [10] Treatment : mainly supportive References: [13] [14] [15] [16] [17] [11] [18] [10][amboss.com] […] myopathies ” below Diagnostics Genetic studies (including mitochondrial DNA ) Muscle biopsy : immunohistochemistry typically shows " ragged red fibers ", which are caused by subsarcolemmal[amboss.com]

  • Genetic Recurrent Myoglobinuria

    An increased immunoreactivity in the subsarcolemmal zone owing to the accumulation of mitochondria was observed (fig 2G).[jmg.bmj.com] Symptoms occurs within first two years of life with Reye's-like episodes of lethargy, vomiting and coma precipitated by fasting state and associated with hypoketotic hypoglycemia[annalsofneurosciences.org] […] encoded subunits II/III showed a virtual absence of immunoreactivity (fig 2F) when compared to control muscle (fig 2E), whereas the nuclearly encoded subunit IV showed a normal[jmg.bmj.com]

  • Autosomal Dominant Myoglobinuria

    In addition, COX can highlight the subsarcolemmal accumulations of mitochondria.[neupsykey.com] Symptoms occurs within first two years of life with Reye's-like episodes of lethargy, vomiting and coma precipitated by fasting state and associated with hypoketotic hypoglycemia[annalsofneurosciences.org] Reduced COX staining can be seen in both ragged red and otherwise normal-appearing muscle fibers.[neupsykey.com]

  • Neonatal Hypoglycemia

    View/Print Table TABLE 1 Clinical Signs Associated with Hypoglycemia* Changes in levels of consciousness Irritability Lethargy Stupor Apnea, cyanotic spells Coma Feeding poorly[aafp.org] […] after feeding well Hypothermia Hypotonia, limpness Tremor Seizures TABLE 1 Clinical Signs Associated with Hypoglycemia* Changes in levels of consciousness Irritability Lethargy[aafp.org]

    Missing: Subsarcolemmal Accumulation of Normal Mitochondria
  • Gram Positive Septicemia

    […] of glucose homeostasis – hypoglycemia or hyperglycemia Hypotension Healthcare-Associated Infections (HAIs) Overview Healthcare associated infections (HAIs) are an important[clinicaladvisor.com] The key symptoms and signs of the disease include: Respiratory distress Apnea Temperature instability Poor feeding Feeding intolerance Lethargy Irritability Seizures Loss[clinicaladvisor.com]

    Missing: Subsarcolemmal Accumulation of Normal Mitochondria
  • Secondary Myopathy

    Symptoms occurs within first two years of life with Reye's-like episodes of lethargy, vomiting and coma precipitated by fasting state and associated with hypoketotic hypoglycemia[annalsofneurosciences.org]

    Missing: Subsarcolemmal Accumulation of Normal Mitochondria
  • Panhypopituitarism

    It can occur in the early hours of life with hyporeactivity, lethargy, severe hypoglycemia.[omicsonline.org] It can occur isolated or associated with ocular defects (septo-optic dysplasia), median line defects, male genital anomalies (micropenis, cryptorchidism, bifid scrotum) [[omicsonline.org]

    Missing: Subsarcolemmal Accumulation of Normal Mitochondria
  • Organic Aciduria

    Neurological damage and developmental delay are common factors in diagnosis, with associated symptoms ranging from poor feeding to slow growth, lethargy, vomiting, dehydration[en.wikipedia.org] Neurological damage and developmental delay are common factors in diagnosis, with associated symptoms ranging from poor feeding to slow growth , lethargy , vomiting , dehydration[ipfs.io] , malnutrition, hypoglycemia, hypotonia, metabolic acidosis, ketoacidosis, hyperammonemia, and if left untreated, death.[en.wikipedia.org]

    Missing: Subsarcolemmal Accumulation of Normal Mitochondria
  • Marasmus

    This can also be associated with infectious states, decreased linear growth, decreased heart rate and blood pressure, thin and dry skin, decreased metabolic rate, lethargy[clinicaladvisor.com] , apathy, thin hair, hypothermia, hypoglycemia, electrolyte imbalances, vitamin deficiency.[clinicaladvisor.com]

    Missing: Subsarcolemmal Accumulation of Normal Mitochondria
  • MELAS Syndrome

    Initially the muscle biopsy may show only muscle fibers with subsarcolemmal accumulation of mitochondria without typical RRF, but all patients with MELAS have RRF in the course[scielo.br] The biochemical analysis of respiratory chain complexes may be normal in some cases. WHAT ARE THE HISTOLOGICAL FEATURES?[scielo.br]

    Missing: Lethargy Associated with Hypoglycemia

Further symptoms