1,094 Possible Causes for Leucine Increased

Did you mean:   leucine decreased

  • Maple Syrup Urine Disease

    Only samples with both increased total leucine and increased alloisoleucine would lead to further metabolic workup.[clinchem.aaccjnls.org] DHA and ARA Isoleucine-, leucine- and valine-free Vitamin and mineral levels meet the U.S.[enfamil.com] (and increase the blood:brain barrier transport of leucine due to less inhibition by isoleucine and valine; increased brain leucine produces or enhances brain edema).[newenglandconsortium.org]

  • Isovaleric Acidemia

    They are often triggered by an infection or by eating an increased amount of protein-rich foods.[en.wikipedia.org] Isovaleric acid accumulates in the blood during periods of increased amino acid metabolism.[medical-dictionary.thefreedictionary.com] Specifically, this enzyme helps process the amino acid leucine, which is part of many proteins.[ghr.nlm.nih.gov]

  • HMG-CoA Lyase Deficiency

    Urinary levels of 3-methylcrotonylglycine may be increased.[malacards.org] 3-hydroxy-3-methylglutaric (HMG)-CoA lyase is required for ketogenesis and leucine degradation.[jhu.pure.elsevier.com] The patient was discharged, and leucine-free formula and L-carnitine were prescribed.[spandidos-publications.com]

  • Multiple Carboxylase Deficiency

    Characteristic biochemical features: plasma: increased lactate and propionate; urine: increased 3-hydroxyisovalerate, methycrotonylglycine, methylcrotonic acid, lactate, methylcitrate[link.springer.com] Figure 75.2. — Leucine pathway showing different enzymatic blocks and the amino acids that increase as a result of the block.[pediatricneuro.com] Plasma free carnitine levels may be very low Treatment Treatment of 3-MCC deficiency involves reducing dietary Leucine intake using a special Leucine-depleted formula or a[path.upmc.edu]

  • Viral Hepatitis
  • Obesity
  • Norepinephrine

    J Clin Invest 1966 ; 45 : 1751 – 68 . 3 Leucine, glucose, and energy metabolism after 3 days of fasting in healthy human subjects .[ajcn.nutrition.org] The increased urea-nitrogen appearance rate on day 3 of our study reflected increased muscle proteolysis.[ajcn.nutrition.org] Conclusions: Resting energy expenditure increases in early starvation, accompanied by an increase in plasma norepinephrine.[ajcn.nutrition.org]

  • Streptococcal Infection

    The serine-rich repeat domain protein Srr-1 binds human keratin 4 ( Samen et al., 2007 ) and the GBS surface protein LrrG, containing the leucine-rich-repeat motif found in[intechopen.com] On the other hand, conditions during pregnancy may lead to increased GBS multiplication in the urogenital tract and GBS can grow to high numbers in human amniotic fluid.[intechopen.com] Trends of increasing antibiotic resistance ( Edwards, 2006 ) may reflect clonal dissemination and horizontal transfer of resistance genes, which occurs among some GBS isolates[intechopen.com]

  • Early-Onset Alzheimer Disease Type 3

    Increasing forgetfulness prompted a medical opinion at the age of 58.[jnnp.bmj.com] Chromosome 14 familial Alzheimer’s disease: the clinical and neuropathological characteristics of a family with a leucine serine (L250S) substitution at codon 250 of the presenilin[jnnp.bmj.com] […] described from a kindred with autosomal dominant familial Alzheimer’s disease associated with a novel mutation in the presenilin 1 (PS1) gene on chromosome 14 that results in a leucine[jnnp.bmj.com]

  • Bronchial Disease

    Recent advances in the study of leucine-rich repeat protein 3 (NLRP3) inflammasome may also provide a potential link between asthma and CKD.[bmcpulmmed.biomedcentral.com] After adjusting for steroid use, the HR of asthma increased, indicating that asthma directly impacts on CKD.[bmcpulmmed.biomedcentral.com] There was decreased HRs in steroid use (HR: 0.56; 95% CI: 0.62-0.61; p Conclusions Patients with bronchial asthma may have increased risk of developing chronic kidney disease[bmcpulmmed.biomedcentral.com]

Further symptoms