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1,887 Possible Causes for Leukemia, Leukopenia

  • Endocrine Dysfunction

    Variable features observed in some patients are progressive ataxia, and lymphopenia or borderline leukopenia.[uniprot.org] Targeting MC1R in metastatic melanoma November 26, 2018 In 1960, scientists described the "Philadelphia chromosome" that causes chronic myeloid leukemia, and in 2001 the Food[medicalxpress.com]

  • Influenza

    Disease I Immunity Immunization Infectious Disease General Inflammatory Bowel Disease Influenza Insurance Coverage International Health Policy K Kidney Transplantation L Leukemia[nejm.org]

  • Infectious Mononucleosis

    Leukopenia and thrombocytopenia are not uncommon.[ncbi.nlm.nih.gov] These include leukemia, Burkitt' lymphoma, pancreatic carcinoma, viral hepatitis, cytomegalovirus infections, and others.[mayomedicallaboratories.com] These causes of false-positive Monospot test results include toxoplasmosis, rubella, systemic lupus erythematosus, and certain malignancies, particularly leukemias and/or[askhematologist.com]

  • Streptococcal Infection

    These include: Blood counts: Both leukopenia and leukocytosis have been reported with relatively equal frequencies. A marked left shift of the differential is common.[clinicaladvisor.com] An elderly man with chronic myelomonocytic leukemia developed respiratory distress and died less than 48 hours after transfusion of a pool of eight whole blood-derived platelets[ncbi.nlm.nih.gov]

  • Primary Myelofibrosis

    We found that fibrosis grade 2 and greater on a 0-3 scale was associated with clinical characteristics indicative of a more advanced disease, such as anemia, leukopenia, thrombocytopenia[ncbi.nlm.nih.gov] A 56-year-old male with chronic idiopathic myelofibrosis and cytogenetic finding of 20q- after a period of 10 months developed acute Philadelphia-positive lymphoblastic leukemia[ncbi.nlm.nih.gov] Compared with pre-PMF, overt PMF was enriched in patients with anemia, thrombocytopenia, leukopenia, higher blast count, symptoms, large splenomegaly, and unfavorable karyotype[ncbi.nlm.nih.gov]

  • Myelodysplasia

    Serum copper determination should be included in the work-up of patients with anemia and leukopenia of unclear etiology who have associated myeloneuropathy.[ncbi.nlm.nih.gov] Therapy-related leukemia (myelodysplasia and acute myeloid leukemia-t-MDS/AML) is a well-known complication of conventional chemoradiotherapy used to treat a variety of primary[ncbi.nlm.nih.gov] Can present with symptoms of anaemia, leukopenia, and thrombocytopenia, but often found during routine laboratory investigations in asymptomatic patients.[bestpractice.bmj.com]

  • Paroxysmal Nocturnal Hemoglobinuria

    CBC showed leukopenia (WBC 2.9 x 103 /µL) with neutropenia (segmented neutrophils 48%), macrocytic anemia (Hgb 6.1 g/dL, hematocrit 20%, MCV,113 fL) and thrombocytopenia ([ncbi.nlm.nih.gov] […] chromosomal abnormalities involving chromosome bands 13q12 to 13q14 (13q12q14) are frequently found in various hematologic malignancies, including chronic lymphoblastic leukemia[ncbi.nlm.nih.gov] Leukopenia, thrombocytopenia, arterial and venous thromboses, and episodic crises are common. Diagnosis requires flow cytometry.[merckmanuals.com]

  • Familial Myelofibrosis

    Blood counts generally reveal normocytic, normochromic anemia, leukopenia, and thrombocytopenia.[symptoma.com] They encode for Janus kinase 2, calreticulin, and myeloproliferative leukemia virus oncogene.[symptoma.com] Thus, patients suffering from myelofibrosis eventually develop anemia, leukopenia, and thrombocytopenia.[symptoma.com]

  • Sideroblastic Anemia

    We report the case of a young woman who presented with anemia and leukopenia. A bone marrow aspirate revealed a marked excess of ringed sideroblasts.[ncbi.nlm.nih.gov] Active hairy cell leukemia is associated with an increase of RDW (Red Cell Distribution Width) which normalizes after successful therapy with 2-chlorodeoxyadenosine (2-CdA[ncbi.nlm.nih.gov] Zinc ingestion or exposure should be considered in the differential diagnosis of unexplained anemia, leukopenia, or sideroblastic anemia.[ncbi.nlm.nih.gov]

  • Chemotherapy

    The main outcomes were improvement in chemotherapy-induced grade 3/4 marrow suppression (leukopenia, neutropenia, anemia, and thrombocytopenia) or gastrointestinal toxicities[ncbi.nlm.nih.gov] Leukemia .[lls.org] Hematological toxicities of Grade 3/4 were leukopenia 50%, neutropenia 68%, and febrile neutropenia 18%.[ncbi.nlm.nih.gov]

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