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224 Possible Causes for Leukemia, Massive Splenomegaly

  • Primary Myelofibrosis

    Abstract Primary myelofibrosis (PMF) is a chronic myeloproliferative neoplasm characterized by progressive anemia, massive splenomegaly, leukoerythroblastosis, extramedullary[ncbi.nlm.nih.gov] A 56-year-old male with chronic idiopathic myelofibrosis and cytogenetic finding of 20q- after a period of 10 months developed acute Philadelphia-positive lymphoblastic leukemia[ncbi.nlm.nih.gov] She also underwent splenectomy when she was 13 years old, due to massive splenomegaly, anemia and various infection disease episodes.[ncbi.nlm.nih.gov]

  • Hypersplenism

    CONCLUSION: Our results demonstrate that shunt surgery with partial resection of the spleen is effective and safe for pediatric patients with massive splenomegaly and severe[ncbi.nlm.nih.gov] Abstract A 45-year-old woman with previously diagnosed chronic type adult T-cell leukemia (ATL) presented with abdominal discomfort and red eruptions on her arms and legs.[ncbi.nlm.nih.gov] Apart from a strongly positive Mantoux test, all investigations for massive splenomegaly proved negative.[ncbi.nlm.nih.gov]

  • Chronic Myeloid Leukemia

    Here, we report a case of aCMLin a 5-month baby who presented with massive splenomegaly. The diagnosis was in accordance with the WHO criteria established in 2008.[ncbi.nlm.nih.gov] What You Should Know Chronic myeloid leukemia (CML) is also called chronic myelogenous leukemia, chronic granulocytic leukemia and chronic myelocytic leukemia.[lls.org] Massive splenomegaly is characteristic and may cause left hypochondral pain.[gpnotebook.co.uk]

  • Blast Phase

    The findings of massive splenomegaly, basophilia, and thrombocytosis point toward CML. Our patient had massive splenomegaly and basophilia but a normal platelet count.[ecancer.org] […] myeloid leukemias (CML).[books.google.com] Given the presence of constitutional symptoms and massive splenomegaly, the patient inquired about treatment with the JAK inhibitor ruxolitinib.[bloodjournal.org]

  • Leukemia

    Splenomegaly can be massive, consistency high, with the fibrous thickening of the capsule.[web.archive.org] There are basically 4 types of leukemia, namely: Acute lymphocytic leukemia, acute myelogenous leukemia, chronic lymphocytic leukemia and chronic myeloid leukemia.[symptoma.com] Thus, the four major types of leukemia are: Acute Lymphocytic Leukemia Chronic Lymphocytic Leukemia Acute Myelogenous Leukemia Chronic Myelogenous Leukemia Acute leukemia[web.archive.org]

  • Myeloproliferative Disease

    […] in 75% of patients * is due to extramedullary hematopoiesis (takes place in liver as well) * may be massive extending to the pelvic brim * splenic infarcts common with massive[quizlet.com] There are two big categories of leukemias: acute leukemias and chronic leukemias.[pathologystudent.com] M3 leukemias were rather low in CD11a expression.[ncbi.nlm.nih.gov]

  • Paroxysmal Nocturnal Hemoglobinuria

    We describe a patient under treatment with the anti-complement antibody eculizumab who developed pancytopenia, requiring blood transfusions, due to massive splenomegaly.[ncbi.nlm.nih.gov] It may be associated with aplastic anemia , myelodysplastic syndrome, or acute myelogenous leukemia . Risk factors, except for prior aplastic anemia, are not known.[nlm.nih.gov] Other features include weakness, abdominal and lumbar pain, jaundice with pallor and yellowish discoloration of the skin and mucous membranes, heart murmurs, splenomegaly,[whonamedit.com]

  • Chronic Phase of Chronic Myeloid Leukemia

    Chronic myelogenous leukemia (CML) is a myeloproliferative disease also referred to as chronic myeloid leukemia.[symptoma.com] , Myeloid, Chronic-Phase/diagnosis Leukemia, Myeloid, Chronic-Phase/drug therapy* Leukemia, Myeloid, Chronic-Phase/genetics Male Middle Aged Patched-1 Receptor/physiology*[ncbi.nlm.nih.gov] In this phase, the CML acts a lot like an acute leukemia.[cancer.org]

  • Prolymphocytic Leukemia

    A 69-year-old woman was admitted to our hospital because of massive splenomegaly and leukocytosis.[ncbi.nlm.nih.gov] Described as a type of leukemia having a rather poor prognosis, prolymphocytic leukemia (PLL) is a rare lymphoid malignancy of mature T or B cells.[symptoma.com] This is a rare chronic lymphoproliferative disorder seen in elderly in which patients have high total leukocyte count along with massive splenomegaly.[medical-labs.net]

  • Hairy Cell Leukemia

    Also these cytokines may play a role in the development of hairy cell leukemia.Key words: hairy cell leukemia - sarcoidosis - massive splenomegaly.[ncbi.nlm.nih.gov] Hairy cell leukemia (HLC) is a rare, chronic form of B-lymphocytic leukemia.[symptoma.com] Abstract Hairy cell leukemia (HCL) is a chronic B-cell leukemia noted for an indolent course that ultimately results in cytopenias and massive splenomegaly.[ncbi.nlm.nih.gov]

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