10,482 Possible Causes for Leukocyte Alkaline Phosphatase Decreased

  • Rathbun Syndrome

    Hypophosphatasia is a hereditary disorder characterized by a deficiency of liver/bone/kidney alkaline phosphatase activity in serum and tissues with defective bone mineralization[ncbi.nlm.nih.gov] There may be elevations in transaminase levels, as well as in alkaline phosphatase, blood urea nitrogen, serum creatinine, and lactic dehydrogenase levels.[academic.oup.com] […] likelihood of developing diseases such as Huntington’s disease, a disease resulting from trinucleotide repeat on chromosome 4p16.3 that causes uncontrollable muscle movement and decrease[123helpme.com]

    Missing: leukocyte
  • Infectious Mononucleosis

    The chemistry panel showed aspartate aminotransferase of 212 U / L, alanine aminotransferase of 274 U / L, and alkaline phosphatase of 788 U / L.[journalmc.org] Admixed with this lymphocytic infiltrate, but in relatively minimal numbers, were a few plasma cells and polymorphonuclear leukocytes.[link.springer.com] […] in about 10% of patients) Increased ALT, AST, and lactic acid dehydrogenase levels in blood Jaundice (occurs in about 5% of cases) Early in illness, cutaneous anergy and decreased[atsu.edu]

  • X-Linked Hypophosphatemia

    Diagnosis [ edit ] Begin clinical laboratory evaluation of rickets with assessment of serum calcium, phosphate, and alkaline phosphatase levels.[en.wikipedia.org] , elevated alkaline phosphatase, decreased PTH 4 Elevated serum phosphate, elevated alkaline phosphatase, elevated PTH 5 Elevated serum phosphate, decreased alkaline phosphatase[orthobullets.com] Diagnosis is by serum phosphate, alkaline phosphatase, and 1,25-dihydroxyvitamin D 3 levels.[merckmanuals.com]

    Missing: leukocyte
  • Chronic Phase of Chronic Myeloid Leukemia

    (or neutrophil) alkaline phosphatase (LAP, or NAP) score can be helpful in excluding a reactive leukocyotsis or leukemoid rxn (LAP score is elevated or normal) from a leukemic[errolozdalga.com] Cytochemistry : leukocyte alkaline phosphatase (LAP) Cytogenetics : confirmation of BCR-ABL ( Philadelphia chromosome ) fusion gene Low LAP is a distinct feature of CML that[amboss.com] The proportion of immature cells and the leukocyte alkaline phosphatase score may increase.[merckmanuals.com]

    Missing: decreased
  • Chronic Myeloid Leukemia

    The proportion of immature cells and the leukocyte alkaline phosphatase score may increase.[merckmanuals.com] This includes measuring the activity of the alkaline leukocyte phosphates (ALP).[aoporphan.com] The leukocyte alkaline phosphatase test is largely of historical interest, as it has been superseded by cytogenetic tests; however, it was used previously to differentiate[patient.info]

    Missing: decreased
  • Renal Cell Carcinoma

    Charnow, Editor December 12, 2017 Levels of alkaline phosphatase, calcium, and hemoglobin can independently predict bone metastasis in patients with renal cell carcinoma,[renalandurologynews.com] It contains alkalinity (to slow down the spreading of the cancer), things that build the immune system and things that can kill cancer cells.[cancertutor.com] phosphatase, and LDH. 24 Although various prognostic models exist, robust clinical and biologic features predictive of outcome in patients with metastatic RCC are scarce.[clevelandclinicmeded.com]

    Missing: leukocyte decreased
  • Reticulosarcoma

    phosphatase levels CT scanning of the neck, chest, abdomen, and pelvis: To help identify degree of lymphadenopathy, presence of extranodal disease, or visceral involvement[emedicine.medscape.com] Activation antigens are variably expressed by diffuse large B-cell lymphomas, with human leukocyte antigen (HLA)-DR being the most frequent and CD23 being expressed uncommonly[emedicine.medscape.com] Treatment that includes aggressive intravenous hydration, urine alkalinization, and administration of allopurinol usually prevents tumor lysis syndrome.[emedicine.medscape.com]

    Missing: decreased
  • Hodgkin's Disease

    Increases in leukocyte alkaline phosphatase, serum haptoglobin, and other acute-phase reactants usually reflect active disease.[merckmanuals.com] Staging and risk assessment FBC, ESR and blood chemistry including CRP, alkaline phosphatase, LDH, liver enzymes, albumin and TSH. [ 5 ] Pre-treatment blood evaluation should[patient.info] Unique staining profile for L & H variants of Reed-Sternberg cells defined by monoclonal antibodies to leukocyte common antigen, granulocyte-specific antigen, and B-cell-specific[jco.ascopubs.org]

    Missing: decreased
  • Paroxysmal Nocturnal Hemoglobinuria

    Leukocytes have a low alkaline phosphatase score as in chronic myeloid leukaemia.[patient.info] Labs reveal Hb 6.7 g/dL, leukocyte count of 5,000/mm 3 , platelets of 100,000/mm 3 ,high reticulocyte count, and high LDH.[medbullets.com] Activation : can be used at night to decrease nocturnal hemolysis Androgens Decrease Complement Activation : decreases hemolysis Increase Red Blood Cell Production : decreases[mdnxs.com]

  • Acute Myelocytic Leukemia

    Laboratory and physical findings include enlarged spleen (splenomegaly), a high white blood cell count, and absent or low amounts of the white blood cell enzyme alkaline phosphatase[healthcommunities.com] […] platelet count, and anemia due to decreased erythrocyte count.[medical-dictionary.thefreedictionary.com] phosphatase, bilirubin, lactate dehydrogenase levels Calcium, phosphorus levels Partial thromboplastin time, activated partial thromboplastin time, fibrinogen, D dimer Bone[clevelandclinicmeded.com]

    Missing: leukocyte

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