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13 Possible Causes for Leukocyte Alkaline Phosphatase Decreased, Occult Malignancy, Thrombocytosis

  • Non-Hodgkin Lymphoma

    In the first case, the laboratory tests showed anemia, thrombocytosis, elevated inflammatory biomarkers, a low level of iron, and hypoproteinemia.[] Thrombocytosis and lymphocytosis may also occur. Renal function and electrolytes: obstructive nephropathy, hypercalcaemia. LFTs. Serology: HIV, HTLV-1, hepatitis C.[] […] the following: CBC count: May be normal in early-stage disease; in more advanced stages, may demonstrate anemia, thrombocytopenia/leukopenia/pancytopenia, lymphocytosis, thrombocytosis[]

  • Adenocarcinoma of the Breast

    Adenocarcinoma of the breast is a term encompassing several types of tumors such as ductal and lobular carcinomas. An asymptomatic painless mass is usually the only symptom in the early stages, whereas an array of constitutional and localized symptoms may be seen in more advanced disease. Mammography and other[…][]

  • Bronchogenic Carcinoma

    […] metastases from lung cancer may present clinically or as a finding at autopsy. [3] Clinically they present with symptoms of colonic obstruction, lower gastrointestinal bleed (occult[] […] the appearance of pan colitis in this case could be from the extensive tumour involvement of colonic mucosa and excessive proliferative activity of a poorly differentiated malignancy[]

  • Cecal Adenocarcinoma

    Most importantly, for patients with blood cultures that grow C. septicum , a comprehensive search for occult malignancy is imperative, especially for adenocarcinomas in the[] According to this definition, the sign may be present with or without occult malignancy and is detectable on history and physical examination alone.[] malignancy [ 2 ].[]

  • Hodgkin Lymphoma

    The endobronchial localization of Hodgkin's disease is a rare entity which is often confused with endobronchial tuberculosis in our setting. We report the case of a 16 years old female who presented with 6 months history of dry cough, hemoptysis, dyspnea, dysphagia and dysphonia. The chest radiography showed a[…][]

  • Renal Cell Carcinoma

    We describe a unique case of subcutaneous metastasis of sarcomatoid renal cell carcinoma which was the first manifestation of the occult malignancy.[] Her admission analysis reported haemoglobin 6.5 g/dl, thrombocytosis 797 10 3 /mm 3, leukocytosis 14.7 10 3 /mm 3 with neutrophilia of 12.9 10 3 /mm 3 and elevated C reactive[] In cases where the oral lesion represents the initial presentation of an occult primary malignancy, additional workup including full body imaging is recommended to determine[]

  • Metastatic Renal Cell Carcinoma

    On interaction term analyses, the beneficial effect of CN increased with better performance status (P 0.06), in women (P 0.03), and in patients with thrombocytosis (P 0.01[] […] from initial diagnosis to systemic treatment Karnofsky index 80% LDH 1.5xN Hemoglobin Serum calcium 10 mg/dl The presence of neutropenia (Heng’s criteria) The presence of thrombocytosis[]

  • Bone Marrow Disease

    Some of the transplant centers, including ours, use bone marrow aspiration on related donors to exclude occult hematological malignancies.[] Essential thrombocytosis (primary thrombocythemia): The body produces too many platelets, due to an unknown cause; the platelets do not work properly, resulting in excessive[] Essential thrombocythaemia (ET): A disease effecting the megakaryocytes resulting in a high platelet count (thrombocytosis).[]

  • Leukoerythroblastic Anemia

    Increased C-reactive protein suggests but does not secure a diagnosis of reactive thrombocytosis associated with an occult inflammatory or malignant process.[] leukocyte alkaline phosphatase score in CML LAP is absent in neoplastic granulocytes and present in benign granulocytes Treatment of CML imatinib mesylate: oral tyrosine[] […] myeloproliferative neoplasm neonatal anemia normocytic anemia pancytopenia pure red-cell aplasia Refractory Anemia sideroblastic anemia Thrombocytopenia, Anemia, and Myelofibrosis thrombocytosis[]

  • Hereditary Neutrophilia

    In addition, a history of smoking, along with evidence for a chronic anxiety state or an occult malignancy, should be sought.[] Hereditary thrombocytosis was first linked to mutations in genes encoding thrombopoietin (THPO) or the thrombopoietin receptor, MPL.[] […] megakaryocytes Decreased erythroid precursors Leukocyte alkaline High Absent phosphatase Table 9-6.[]

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