10,588 Possible Causes for Leukocyte Alkaline Phosphatase Increased

  • Extrahepatic Cholestasis

    Alkaline Phosphatase (ALP) Alkaline phosphatase refers to a family of enzymes that catalyze hydrolysis of phosphate esters at an alkaline pH.ALP is present (in decreasing[clinlabnavigator.com] Parallel changes occurred in 5′-nucleotidase, suggesting a hepatic origin for the alkaline phosphatase activity.[annals.org] Serum γ-glutamyltransferase, aspartate aminotransferase and alkaline phosphatase.[degruyter.com]

    Missing: leukocyte increased
  • Massive Hepatic Necrosis

    […] elevation of serum alkaline phosphatase and bilirubin.[annals.org] AMA & ANA positive with Alkaline phosphatase 2 upper limit of normal & one ALT 5 times upper limit of normal.[librepathology.org] Drug-Induced Hepatic Necrosis DEFINITION Sudden abnormality of liver biochemical tests (alanine aminotransferase, alkaline phosphatase and/or bilirubin) with underlying liver[demosmedical.com]

    Missing: leukocyte increased
  • Cholestasis

    phosphatase .[nlm.nih.gov] Liver enzyme studies typically show an elevation of the alkaline phosphatase level.[clevelandclinicmeded.com] Blood tests on admission showed bilirubin 651 µmol/L (normal range 0 to 19), alanine aminotranferase 76 IU/L (0 to 45), alkaline phosphatase 262 IU/L (35 to 120), and international[bmj.com]

    Missing: leukocyte increased
  • Liver Failure

    Alkaline phosphatase (ALP): Alkaline phosphatase is a group of enzymes that are produced in various parts of the body including the intestine, kidneys and bones. 4.[thehealthsite.com] […] or the phenomenon of membrane blebbing, and membrane-affiliated enzyme induction (alkaline phosphatase [ALP], γ-glutamyl transferase [GGT]) reflecting cholestasis and increased[merckvetmanual.com] Alkaline phosphatase is usually also elevated.[ece.ncsu.edu]

    Missing: leukocyte
  • Macronodular Cirrhosis

    There was a marked increase in the levels of the serum albumin, SGOT, and alkaline phosphatase ( Fig 1 ); prothrombin activity was 50% of normal.[pubmedcentralcanada.ca] Diagnostic tests include abnormal liver function studies, including elevations in alkaline phosphatase, aminotransferase, and alanine aminotransferase.[medical-dictionary.thefreedictionary.com] Alkaline phosphatase elevation can occur with extrahepatic obstruction, primary biliary cirrhosis, and primary sclerosing cholangitis. 6.[encyclopedia.lubopitko-bg.com]

    Missing: leukocyte
  • Metastatic Liver Carcinoma

    Features [ edit ] Hepatomegaly - with a nodular free edge of liver Tenderness Cachexic Ascites Jaundice Pyrexia - up to 10% of patients Alkaline Phosphatase ( ALP ) and gamma[en.wikipedia.org] However, liver function tests were altered, showing increased transaminases and alkaline phosphatase [Table 1] .[jcmtjournal.com] Laboratory investigations revealed mildly elevated levels of aspartate aminotransferase (43 U/L [15-33U/L]), alkaline phosphatase (122 U/L [32-103U/L]) and gamma-glutamyl[jddonline.com]

    Missing: leukocyte
  • Viral Hepatitis

    Transaminases such as aspartate aminotransferase (AST) and alanine aminotransferase (ALT), bilirubin, and alkaline phosphatase are generally elevated.[nutritionmd.org] Some patients experience a cholestatic hepatitis, marked by the development of an elevated alkaline phosphatase (ALP) level, in contrast to the classic picture of elevated[emedicine.medscape.com] Alkaline phosphatase (ALP) – an enzyme related to the bile ducts but also found in other tissues throughout the body.[labtestsonline.org]

    Missing: leukocyte increased
  • Portal Cirrhosis

    Diagnostic tests include abnormal liver function studies, including elevations in alkaline phosphatase, aminotransferase, and alanine aminotransferase.[medical-dictionary.thefreedictionary.com] Blood tests LFTs: should include aspartate transaminase (AST), alanine transaminase (ALT), alkaline phosphatase (ALP), bilirubin, gamma-glutamyltransferase (gamma-GT); AST[patient.info] This disparity is attributed to a sixfold increase in patients on the transplant waiting list from 1991 to 2001 and a much slower rate of increase in the donor pool.[aafp.org]

    Missing: leukocyte
  • Ulcerative Colitis

    There may even be human leukocyte antigen associations at work.[en.wikipedia.org] Liver function tests should be done; elevated alkaline phosphatase and gamma-glutamyl transpeptidase levels suggest possible primary sclerosing cholangitis.[merckmanuals.com] Colonic adenocarcinoma develops in 3-5% of patients with ulcerative colitis, and the risk increases as the duration of disease increases.[emedicine.medscape.com]

  • Hepatocellular Carcinoma

    Mild elevations in liver transaminases as well as alkaline phosphatase can be present.[karger.com] The incidence of HCC in the United States and other developing countries is increasing due to an increase in hepatitis C virus infections.[en.wikipedia.org] […] an increased risk of HCC.[emedicine.medscape.com]

    Missing: leukocyte

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