Possible Causes for Leukocyte Alkaline Phosphatase Increased in USA

  • Acute Lymphoblastic Leukemia
    Leukocyte Alkaline Phosphatase Increased

    Acute lymphocytic leukemia (ALL) is a type of cancer that affects the bone marrow, and, subsequently, the blood. It can occur at any age, but children are most commonly affected by it. The bone marrow is a vital organ, that is responsible for the production and maturation of all of the cellular components of the…[1]

  • Reticulosarcoma
    Leukocyte Alkaline Phosphatase Increased Leukocyte Alkaline Phosphatase Decreased
  • Chronic Lymphocytic Leukemia
    Leukocyte Alkaline Phosphatase Increased Leukocyte Alkaline Phosphatase Decreased

    Treatment is subjective to the stage of the disease. Since it does not have any definite cure, treatment focuses on improving the quality and quantity of life. Optimum therapy includes a combination of radiotherapy and chemotherapy, which may or may not be accompanied with surgery for existing complications such…[2]

  • Polycythemia Vera
    Leukocyte Alkaline Phosphatase Increased

    The goal of treatment for polycythemia vera is to control myeloproliferation and decrease the risk of arterial and venous thrombotic events, which occur in approximately 20% of patients. The optimum management plan is unclear. Significant differences exist among physicians about the appropriate management of the…[3]

  • Primary Myelofibrosis
    Leukocyte Alkaline Phosphatase Increased

    High incidence rates among survivors of the atomic bombings hint at radiation as a possible etiologic factor, but the precise trigger of hematopoietic stem cell transformation is still unknown. However, genome analyses revealed certain anomalies that are frequently shown by PMF patients. A determined somatic…[4]

  • Hodgkin's Disease
    Leukocyte Alkaline Phosphatase Increased Leukocyte Alkaline Phosphatase Decreased

    Jaffe ES, Harris NL, Stein H, Vardiman JW, eds. World Health Organization Classification of Tumours: Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues. Lyon, France: IARC Press; 2001. Staal SP, Ambinder R, Beschorner WE, Hayward GS, Mann R. A survey of Epstein-Barr virus DNA in lymphoid tissue.…[5]

  • Myeloproliferative Disease
    Leukocyte Alkaline Phosphatase Increased

    CML The pathophysiology of CML is explained by the underlying tyrosine kinase that exhibits a gain of function characteristic, which leads to the excessive production of granulocytes as well as red blood cells, megakaryocytes, monocytes, etc. The clinical course of CML evolves over three stages which are the…[6]

  • Klinefelter Syndrome
    Leukocyte Alkaline Phosphatase Increased

    Klinefelter syndrome is the most common chromosomal aberration in men. Approximately 1 in 500-1,000 males are born with an extra sex chromosome. More than 3,000 infant males affected with the disorder are born yearly. In 1959, Klinefelter syndrome was found to be caused by one or more extra X chromosomes in male…[7]

  • Myelodysplasia
    Leukocyte Alkaline Phosphatase Increased

    Bone marrow studies and a complete blood count including differential and peripheral blood smear are the diagnostic tests used in MDS. Disease is staged for assessing prognosis and also for planning treatment modality. Peripheral blood smear may show single cytopenia in the early stages which may develop into…[8]

  • Agranulocytosis
    Leukocyte Alkaline Phosphatase Increased

    Agranulocytosis is a condition which is characterized by decrease in the neutrophil count below 100/mL of blood. These blood cells play a key role in the elimination of pathogens. Initial signs and symptoms of agranulocytosis include onset of sudden fever accompanied by chills with development of weakness in hands and…[9]

Further symptoms


  1. Acute Lymphoblastic Leukemia, Symptoma
  2. Chronic Lymphocytic Leukemia, Symptoma
  3. Polycythemia Vera, Symptoma
  4. Primary Myelofibrosis, Symptoma
  5. Hodgkin's Disease, Symptoma
  6. Myeloproliferative Disease, Symptoma
  7. Klinefelter Syndrome, Symptoma
  8. Myelodysplasia, Symptoma
  9. Agranulocytosis, Symptoma