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23 Possible Causes for Leukocyte Alkaline Phosphatase Increased, Night Sweats, Shoulder Pain

  • Primary Myelofibrosis

    alkaline phosphatase (LAP) score is increased Treatment Reduced intensity allogeneic stem cell transplant if intermediate to high risk or palliation of extramedullary hematopoiesis[pathologyoutlines.com] Splenic infarcts, perisplenitis, or subcapsular haematoma may cause severe left upper quadrant or left shoulder pain.[patient.info] Constitutional symptoms, such as night sweats, pruritus, weight loss and fever may be treated with Jakafi.[mpnresearchfoundation.org]

  • Myeloproliferative Disease

    A myeloproliferative disorder manifested by thrombocytosis, a high leukocyte alkaline phosphatase (LAP) score and an increased red blood cell mass was found in a 64-yr-old[ncbi.nlm.nih.gov] […] joint(s) secondary to gouty arthritis that is secondary to hyperuricemia Priapism, tinnitus, or stupor from leukostasis Left upper quadrant and left shoulder pain as a consequence[emedicine.com] Patients usually present with fatigue, weight loss, anemia, night sweats, and splenomegaly.[icd9data.com]

  • Familial Myelofibrosis

    sweats, increased infection, thrombosis, bleeding episodes Late stages associated with portal hypertension, congestive heart failure and acute leukemia Diagnosis Need 3 major[pathologyoutlines.com] Management of constitutional symptoms Multiple symptoms, such as fatigue, weakness, abdominal pain, cachexia, weight loss, pruritus, night sweats and bone pain are common[onlinelibrary.wiley.com] […] inherited forms exist Clinical features May be asymptomatic in early stages Often presents with hepatosplenomegaly and nonspecific symptoms, such as fatigue, weight loss, night[pathologyoutlines.com]

  • Non-Hodgkin Lymphoma

    A 54-year-old female patient presented with two-month history of bilateral shoulder pain, which had exacerbated for 6 days prior to admission.[ncbi.nlm.nih.gov] They are characterized especially by painless adenopathy, fever, night sweats, fatigue and weight loss.[symptoma.com] A patient with virologically controlled human immunodeficiency virus (HIV) infection presented with a 'numb chin' on the background of long-standing night sweats, malaise[ncbi.nlm.nih.gov]

  • Crohn's Disease

    Chitu Okoli, The View from Giantss Shoulders: Developing Theory with Theory-Mining Systematic Literature Reviews, SSRN Electronic Journal, 10.2139/ssrn.2699362, (2015).[doi.org] Crohn's Disease Symptom Tips Fever and night sweats can be Crohn's symptoms. Talk with your doctor to be sure.[web.archive.org] sweats Loss of normal menstrual cycle Even if you think you are showing signs of Crohn’s disease symptoms, only proper testing performed by your doctor can render a diagnosis[ccfa.org]

  • Agranulocytosis

    A 67-year-old Caucasian man arrived at the emergency room with right shoulder pain and weakness that radiated to his right chest, back, and right arm.[ncbi.nlm.nih.gov] See also [ edit ] Cold chill Fever Goose bumps Night sweats Shivering References [ edit ] External links [ edit ][en.wikipedia.org] Given the patient’s persistent right shoulder pain, aspiration of the right shoulder was performed and revealed 227,300 WBCs with 100% segmented neutrophils.[academic.oup.com]

  • Acute Myelocytic Leukemia

    Although reduced leukocyte alkaline phosphatase activity is seen in CML, this is not a specific finding. CML has the following three clinical phases: Chronic phase.[cancer.gov] pain for an enlarged spleen or splenic rupture Acute Respiratory Distress Syndrome (ARDS) ARDS has been reported in patients receiving NEUPOGEN Evaluate patients who develop[neupogenhcp.com] sweats easy bruising or petechiae (tiny red spots on the skin caused by easy bleeding) bone and joint pain belly pain (caused by the build-up of cells in organs like the[kidshealth.org]

  • Post-Polycythemia Vera Myelofibrosis

    […] of the alkaline phosphatase occurs as well.[cancertherapyadvisor.com] Most common symptoms are night sweats, unexplained fever of 37.5 C and weight loss of more than 10% in the last 6 months.[symptoma.com] Splenic infarcts, perisplenitis, or subcapsular haematoma may cause severe left upper quadrant or left shoulder pain.[patient.info]

  • Ulcerative Colitis

    Abstract In 2013 a 40 year old man came to visit in our Rheumatology Unit because of a recent bilateral shoulder and hip pain.[ncbi.nlm.nih.gov] Corticosteroids, which are given to patients with moderate to severe symptoms, have numerous side effects, including a puffy face, excessive facial hair, night sweats, insomnia[draxe.com] (RUQ), right rib pain, right flank pain, right shoulder pain Clinical (history & physical exam) Imaging: FAST examination, CT of abdomen and pelvis Diagnostic peritoneal[en.wikipedia.org]

  • Leukemoid Reaction

    Unlike CML, leukocyte alkaline phosphatase is increased and the bcr/abl translocation is absent.[wakemedicine.wordpress.com] A previously healthy 16-year-old male presented with a 10-day history of shoulder and back pain. He denied having a cough, sputum or dyspnea.[lungindia.com] She did not complain of cough, dyspnea, fever or night sweats. Her weight remained constant.[jmedicalcasereports.biomedcentral.com]

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