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41 Possible Causes for Leukocyte Alkaline Phosphatase Increased, Polycythemia Vera

  • Myeloproliferative Disease

    Abstract A myeloproliferative disorder manifested by thrombocytosis, a high leukocyte alkaline phosphatase (LAP) score and an increased red blood cell mass was found in a[] Polycythemia vera, essential thrombocythemia, and idiopathic myelofibrosis are clonal myeloproliferative disorders arising from a multipotent progenitor.[] Bone marrow fibrosis is also detected in the spent phase of chronic myelogenous leukemia and polycythemia vera. See Workup for more detail.[]

  • Polycythemia Vera

    How is polycythemia vera treated?[] Symptoms Many people with polycythemia vera don't have signs or symptoms.[] Polycythemia vera is a rare chronic myeloproliferative disorder. An increase in red cell mass is the primary feature of polycythemia vera (PV).[]

  • Primary Myelofibrosis

    CONTEXT: Megakaryocytes are the "hallmark" of Philadelphia chromosome-negative myeloproliferative neoplasms, such as essential thrombocythemia, polycythemia vera, and primary[] RATIONALE: This case report describes the progression of primary myelofibrosis (PMF) to polycythemia vera (PV), and discuss its potential mechanisms.[] Objectives: To compare the mutational profiles of patients with primary myelofibrosis (PMF), polycythemia vera (PV), and essential thrombocytosis (ET).[]

  • Familial Myelofibrosis

    For instance, polycythemia vera may be inherited in an autosomal dominant manner and predisposes to myelofibrosis.[] On the one hand, it may be triggered by radiation, infection, and hematological diseases like polycythemia vera, essential thrombocythemia, and leukemia.[] It may be triggered by radiation, pathogens like mycobacteria, human immunodeficiency virus, and fungi, but myelofibrosis may also arise from polycythemia vera, essential[]

  • Leukoerythroblastic Anemia

    The leukocyte alkaline phosphatase score is normal or increased, and the karyotype of remaining normal marrow cells is intact.[] vera; PMF primary myelofibrosis; ET essential thrombocythemia Hematolymphoid Disorders with Thrombocytosis CML PV PMF, Cellular Phase ET RARS-T 5q- Tyrosine kinase ABL p230[] vera; protracted x-ray treatment followed by a myelosclerotic syndrome. ( 14932790 ) ROSELSEN E....OHLSEN S. 1952 16 Metastases in bone marrow and myelophthisic anemia from[]

  • Leukemoid Reaction

    Unlike CML, leukocyte alkaline phosphatase is increased and the bcr/abl translocation is absent.[] vera, and Hodgkin's disease, in active regeneration of the bone marrow, massive hemorrhage, granulocytopenia, diseases of the bone and bone marrow, malignant metastases,[] The leukemoid reaction is distinguished from chronic myelogenous leukemia by an increased leukocyte alkaline phosphatase, and generally, lack of thrombocytopenia.[]

  • Myelodysplasia

    Vera , Fibrotic Phase History of PV / JAK2 Essential Thrombocythemia , Fibrotic Phase (rare) History of ET / may be JAK2 CML , Fibrotic Phase History of CML / BCR-ABL1 MDS[] ICD-10-CM Codes › C00-D49 Neoplasms › D37-D48 Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes › D46- Myelodysplastic syndromes › Myelodysplastic[] Differential Diagnosis Other hematolymphoid disorders Non-neoplastic simulators Hematolymphoid Disorders with Marrow Fibrosis (overview) Disorder Distinguishing Feature(s) Polycythemia[]

  • Essential Thrombocythemia

    Granulocytes from patients with myeloproliferative disorders were previously shown to be functionally activated, as indicated by increased values for leukocyte alkaline phosphatase[] This review provides our current management strategy of patients with polycythemia vera and ET. Copyright 2016 Elsevier Inc. All rights reserved.[] vera.[]

  • Acute Erythroblastic Leukemia

    . : Acute erythermic myelosis as a terminal stage of polycythemia vera. Acta path, microbiol. scand. 50 , 156 (1960).[] Three patients had a previous diagnosis of myeloproliferative disorder (one patient with polycythemia vera, one with essential thrombocythemia and one with both polycythemia[] PubMed CrossRef Google Scholar Eastman , P. , Wallerstein , R.O. , Schrier , S.L. : Conversion of polycythemia vera to chronic Di Guglielmo’s syndrome. J. Amer. med.[]

  • Chronic Lymphocytic Leukemia

    The association of chronic lymphocytic leukemia with polycythemia vera is a rare event with only a few cases of coexistence ever reported.[] Polycythemia vera is a Philadelphia chromosome-negative myeloproliferative neoplasm. Chronic lymphocytic leukemia is a monoclonal expansion of a CD5 CD19 B lymphocytes.[]

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