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326 Possible Causes for Leukocyte Alkaline Phosphatase Increased, Reticulocyte Count Decreased, Wide Space Between the First and Second Toe

  • Non-Hodgkin Lymphoma

    Homepage Rare diseases Search Search for a rare disease Non-Hodgkin lymphoma Disease definition Non-Hodgkin malignant lymphomas(NHL) is a heterogeneous group of malignant tumors of the lymphoid system. ORPHA:547 Synonym(s): NHL Prevalence: 1-5 / 10 000 Inheritance: - Age of onset: Adult ICD-10: - OMIM: 605027[…][orpha.net]

    Missing: Wide Space Between the First and Second Toe
  • Leukoerythroblastic Anemia

    leukocyte alkaline phosphatase: 100 score; increased vitmain B12 900 pg/mL or B12 binding protein 2200 pg/mL Treatment of polycythemia vera phlebotomy to reduce hyperviscosity[memorize.com] Decreased count - reticulocyte levels drop where there is marrow infiltration (leukaemia, myeloma, lymphoma or other malignancies) or due to marrow underactivity such as in[patient.info] count- increased (10-15%) after 5-7 days Platelets- increased platelet production Stem cell suppression (environmental insult) causes genetically altered stem cell (express[quizlet.com]

    Missing: Wide Space Between the First and Second Toe
  • Klinefelter Syndrome

    Klinefelter syndrome is a genetic disorder associated with male hypogonadism, gynecomastia and reduced fertility. Other symptoms include erectile dysfunction, osteoporosis, language and learning impairment and behavioral problems. Hypogonadism gynecomastia and infertility are the most common symptoms that suggest a[…][symptoma.com]

    Missing: Wide Space Between the First and Second Toe
  • Primary Myelofibrosis

    alkaline phosphatase (LAP) score is increased Treatment Reduced intensity allogeneic stem cell transplant if intermediate to high risk or palliation of extramedullary hematopoiesis[pathologyoutlines.com] , and polychromatophilia and very elevated reticulocyte counts can occur. 263,264 The antiglobulin (Coombs) test usually is negative, but red cell autoantibodies can develop[patient-help.com] […] blood counts with immature granulocytes and atypical platelets Later cytopenias develop, more dysplastic cells, teardrop elliptocytes / dacrocytes Leukocyte (neutrophil)[pathologyoutlines.com]

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  • Aplastic Anemia

    For example, for a person with anemia, an inappropriately low reticulocyte count often indicates decrease in red blood cell production in the bone marrow .[labtestsonline.org] For example, for a person with anemia, an inappropriately low reticulocyte count often indicates decrease in red blood cell production in the bone marrow.[labtestsonline.org] The differential white blood count shows a decrease in most types of cells but not lymphocytes .[labtestsonline.org]

    Missing: Wide Space Between the First and Second Toe
  • Septicemia

    Septicemia due to Pasteurella (Mannheimia) haemolytica is a rare occurrence. We report a fatal case of M. haemolytica septicemia in a seven-month-old infant who presented with prolonged fever, sepsis, and pneumonitis without discernable preceding history of animal bites or contact. Rare cases of systemic Mannheimia[…][ncbi.nlm.nih.gov]

    Missing: Wide Space Between the First and Second Toe
  • Myeloproliferative Disease

    A myeloproliferative disorder manifested by thrombocytosis, a high leukocyte alkaline phosphatase (LAP) score and an increased red blood cell mass was found in a 64-yr-old[ncbi.nlm.nih.gov] Leukocyte alkaline phosphatase ( 100 units in the absence of fever or infection). There is no staging system for this disease.[northshore.org] Patients have an increased risk of cardiovascular and thrombotic events and transformation to acute myelogenous leukemia or primary myelofibrosis.[ 5 , 6 , 7 ] Age older than[northshore.org]

    Missing: Wide Space Between the First and Second Toe
  • Myelodysplasia

    History The development of myelodysplastic syndrome (MDS) may be preceded by a few years by an unexplained macrocytic anemia with no evidence of megaloblastic anemia and a mild thrombocytopenia or neutropenia. Clinical symptoms that should prompt a workup for MDS are due to low peripheral blood counts, usually[…][emedicine.medscape.com]

    Missing: Wide Space Between the First and Second Toe
  • Down Syndrome

    A wide space, often with a deep fissure between the first and second toes, is also common.[dx.doi.org] spacing, often with a deep plantar groove between the first and second toes.[dx.doi.org] […] fissures, Brushfield spots, small mouth, small ears, excessive skin at the nape of the neck, single transverse palmar crease, and short fifth finger with clinodactyly and wide[dx.doi.org]

    Missing: Reticulocyte Count Decreased
  • Acute Myelocytic Leukemia

    Although reduced leukocyte alkaline phosphatase activity is seen in CML, this is not a specific finding. CML has the following three clinical phases: Chronic phase.[cancer.gov] Bone marrow aspiration or biopsy reveals hypercellularity with relatively normal granulocytic maturation and no significant increase in leukemic blasts.[cancer.gov]

    Missing: Wide Space Between the First and Second Toe

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