Leukocytes Decreased: Possible Causes & Differential Diagnoses

Influenza
Leukocytes Increased Leukocytes Decreased

Influenza is acommon infectious disease caused by the Influenza virus. Onset is sudden with fever, rhinorrhea, sore throat and headache. Severe myalgias coupled with respiratory tract symptoms are typical of influenza. Patients may also have red, watery eyes and cough. There can also be tachycardia and dyspnea…^[1]
Infectious Mononucleosis
Leukocyte Alkaline Phosphatase Decreased Leukocytes Decreased

Infectious mononucleosis is a common viral infection known to cause pharyngitis and fever. It is primarily an infection of teenagers and young adults caused by the Epstein Barr virus. The majority of patients with infectious mononucleosis have mild symptoms. However a few will complain of the following features: Once…^[2]
Lassa Fever
Leukocytes Decreased

Lassa fever is a potentially fatal viral infection that primarily occurs in West Africa. The virus is spread through contact with rodent secretions and person-to-person transmission is possible through direct contact. The majority of infections are asymptomatic and mild, but in rare cases, severe multiorgan failure…^[3]
Hairy Cell Leukemia
Leukocytes Increased Leukocytes Decreased

Hairy cell leukemia (HLC) is a rare, chronic form of B-lymphocytic leukemia. Patients usually present on diagnosis with pancytopenia, splenomegaly, and circulating hairy cells. All the signs and symptoms of hairy cell leukemia are the result of the proliferation of the abnormal white blood cells. All of the symptoms are…^[4]
Promyelocytic Leukemia
Leukocytes Decreased

Promyelocytic leukemia (PL) is a hematopoietic malignancy and more specifically a type of acute myelogenous leukemia (AML), which is characterized by the increased levels of promyelocytes. Promyelocytes are partly differentiated granulocytes, which develop from a myeloblast into the final, completely differentiated…^[5]
Human Herpesvirus 3
Leukocytes Decreased
Colorado Tick Fever
Leukocytes Decreased

Colorado tick fever is a rare, self-limiting febrile illness caused by an RNA virus of the genus Coltivirus. It is spread through tick bites to people living or traveling in the endemic regions of the western United States and western Canada. It presents clinically with non-specific symptoms, usually in adult males,…^[6]
Babesiosis
Leukocytes Decreased

Babesiosis is an infectious tick-borne caused by protozoa of the genus Babesia. The symptoms manifested in cases of babesiosis are similar to symptoms of malaria. The extent of the symptoms depends on the extent of RBC destruction due to the parasite. The range can be from no overt symptoms to severe…^[7]
Azathioprine
Leukocytes Decreased
Hepatitis B
Leukocytes Decreased

Hepatitis B is a form of viral hepatitis, caused by the hepatitis B virus, a member of the Hepadnavirus family. It is estimated that worldwide, more than 350 million people have chronic hepatitis B virus infection. The course of the disease may be extremely variable, depending on the patient’s age and immune status.…^[8]

Possible Causes for Leukocytes Decreased in USA

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