Create issue ticket

3,464 Possible Causes for Leukocytes Decreased, Retroorbital Pain, Splenomegaly

  • Colorado Tick Fever

    Stiff neck, retroorbital pain, photophobia [ 1 ] , nausea and vomiting, abdominal pain, diarrhea, and sore throat all have been reported in a minority of patients.[emedicine.medscape.com] Splenomegaly may occur. Some patients have altered sensorium or even coma. Complications of Colorado tick fever are unusual and rare.[emedicine.medscape.com]

  • Dengue Fever

    […] of leukocytes and platelets.[ncbi.nlm.nih.gov] […] bitten by mosquitoes, a 60-year-old Japanese female exhibited positive serologic tests of immunoglobulin M and G enzyme immunoassays for dengue viral infection along with a decrease[ncbi.nlm.nih.gov]

  • Rocky Mountain Spotted Fever

    We report a case of Guillain-Barré syndrome (GBS) associated with Rocky Mountain spotted fever (RMSF). The patient initially presented with fever, rash, and an altered mental status, and he responded to therapy with intravenous doxycycline; serological data confirmed RMSF. Concurrent physical findings and results[…][ncbi.nlm.nih.gov]

  • Influenza

    Influenza vaccinations are currently recommended in the care of people with COPD, but these recommendations are based largely on evidence from observational studies, with very few randomised controlled trials (RCTs) reported. Influenza infection causes excess morbidity and mortality in people with COPD, but there[…][ncbi.nlm.nih.gov]

    Missing: Splenomegaly
  • Infectious Mononucleosis

    Clinical estimates of splenomegaly are fallible.[ncbi.nlm.nih.gov] Young adults (15-24) are more likely to be symptomatic. fever tonsillitis lymphadenopathy and splenomegaly fatigue occasionally: rash It was originally called "mononucleosis[radiopaedia.org] In adolescent and adult patients presenting with sore throat, the presence of posterior cervical, inguinal or axillary adenopathy, palatine petechiae, splenomegaly, or atypical[ncbi.nlm.nih.gov]

    Missing: Retroorbital Pain
  • Chediak Higashi Syndrome

    Two of the patients, both with histologic and clinical evidence of the accelerated (infiltrative) phase of the syndrome, had intermittent hypersplenism manifest by splenomegaly[nejm.org] This rare autosomal recessive disorder is characterized by partial oculocutaneous albinism, decreased leukocyte chemotaxis, susceptibility to infection, and death in childhood[ncbi.nlm.nih.gov] Splenomegaly was also present 6 cm below costal margin. Her gait was normal.[omicsgroup.org]

    Missing: Retroorbital Pain
  • Chronic Myelomonocytic Leukemia

    Splenomegaly is frequently seen and may be massive.[ncbi.nlm.nih.gov] Treatment with hydroxyurea (1 g daily) was started, and the patient's leukocyte count decreased to normal within two weeks.[nejm.org] These patients are vulnerable to hepatic toxicity and graft failure after HSCT because of their increased likelihood of portal hypertension, massive splenomegaly, and extensive[ncbi.nlm.nih.gov]

    Missing: Retroorbital Pain
  • Acute Infectious Lymphocytosis

    pain, lethargy/malaise, anorexia/weight loss, N, V, D, meningitis, encephalitis, peripheral neuropathy. - Lab findings: lymphopenia then lymphocytosis, thrombocytopenia,[errolozdalga.com] Patients with infectious mononucleosis are likely to have splenomegaly.[aafp.org] In general, leukopenia may result from decreased marrow production of leukocytic precursors, by peripheral destruction or sequestration of circulating leukocytes, or by autoimmune[antimicrobe.org]

  • Niemann-Pick Disease

    Common disease-related morbidities included splenomegaly (96.6%), hepatomegaly (91.4%), liver dysfunction (82.6%), and pulmonary disease (75.0%).[ncbi.nlm.nih.gov] Acid sphingomyelinase activities of peripheral blood leukocytes were significantly decreased (4.05-21.9 nmol/h/mg protein, normal range 216.1-950.9 nmol/h/mg protein).[ncbi.nlm.nih.gov] Mean annual decreases in platelet count and leukocyte count were 7 10 3 and 0.2 10 3 per mm 3 , respectively.[pediatrics.aappublications.org]

    Missing: Retroorbital Pain
  • Paroxysmal Nocturnal Hemoglobinuria

    PNH is associated with abdominal vein thrombosis, which can cause splenomegaly and hypersplenism.[ncbi.nlm.nih.gov] […] red blood cells Folate/Iron Supplementation (see Folate , [[Folate]] and Iron , [[Iron]]) Usually Required Prednisone (see Prednisone , [[Prednisone]]) Decreases Complement[mdnxs.com] We describe a patient under treatment with the anti-complement antibody eculizumab who developed pancytopenia, requiring blood transfusions, due to massive splenomegaly.[ncbi.nlm.nih.gov]

    Missing: Retroorbital Pain

Similar symptoms