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36 Possible Causes for Leukocytes Decreased, Virus Associated Hemophagocytic Syndrome

  • Malignant Histiocytosis

    The differential diagnosis among hemophagocytic syndromes and particularly between the virus-associated hemophagocytic syndrome (VAHS) and the malignant histiocytosis (HM)[ncbi.nlm.nih.gov] @article{bcdd39714f824a70a344d180d388782a, title "Hyperferritinemia in malignant histiocytosis and virus-associated hemophagocytic syndrome", abstract "There are few clinical[jhu.pure.elsevier.com] Abstract Data on 28 patients with malignant histiocytosis (MH), fourteen patients with virus-associated hemophagocytic syndrome (VAHS) and two patients with familial erythrophagocytic[ncbi.nlm.nih.gov]

  • Infectious Mononucleosis

    Severe chronic active Epstein-Barr virus infection accompanied by virus-associated hemophagocytic syndrome, cerebellar ataxia and encephalitis.[emedicine.medscape.com] Epstein-Barr virus-associated hemophagocytic syndrome and fatal infectious mononucleosis. Am J Hematol. 1996 Oct. 53(2):111-5. [Medline].[emedicine.medscape.com] Epstein-Barr virus-induced infectious mononucleosis after two separate episodes of virus-associated hemophagocytic syndrome. Intern Med. 2009. 48(13):1169-73. [Medline].[emedicine.medscape.com]

  • Influenza Pneumonia

    Virus-associated hemophagocytic syndrome (VAHS) refers to hemophagocytic lymphohistiocytosis due to viral infection.[emcrit.org] Virus-associated hemophagocytic syndrome as a major contributor to death in patients with 2009 influenza A (H1N1) infection. Crit Care. 2011 Mar 2. 15(2):R80. [Medline].[medscape.com] Novel swine-origin influenza A (H1N1) virus-associated hemophagocytic syndrome–a first case report. Am J Trop Med Hyg. 2010;82(4):743-745. [ PubMed ] 48.[emcrit.org]

  • Chediak Higashi Syndrome

    This rare autosomal recessive disorder is characterized by partial oculocutaneous albinism, decreased leukocyte chemotaxis, susceptibility to infection, and death in childhood[ncbi.nlm.nih.gov] In our case, a four-month-old boy, virus-associated hemophagocytic syndrome (VAHS) was suspected from generation of fever, hepatosplenomegaly, and existence of atypical lymphocytes[ncbi.nlm.nih.gov] Partial albinism, pan-leukocytic giant granules, and profoundly decreased NK-cell activity were compatible with childhood CHS, but apparently normal neutrophil function prolonged[ncbi.nlm.nih.gov]

  • Viral Pneumonia

    Virus-associated hemophagocytic syndrome may play an important role in development of multiorgan failure and ensuing death in H1N1 infection. [28] For more information on[emedicine.com] Virus-associated hemophagocytic syndrome as a major contributor to death in patients with 2009 influenza A (H1N1) infection. Crit Care. 2011 Mar 2. 15(2):R80. [Medline].[emedicine.medscape.com] Virus-associated hemophagocytic syndrome as a major contributor to death in patients with 2009 influenza A (H1N1) infection. Crit Care . 2011 Mar 2. 15(2):R80.[emedicine.medscape.com]

  • Sickle Cell Disease

    It also reduces circulating leukocytes, decreasing inflammation. Hydroxyurea therapy has proven to decrease the frequency and severity of crises.[symptoma.com] As the endothelium-derived relaxing factor, NO acts as a vasodilator and also decreases platelet, leukocyte, and endothelial cell activation.[ncbi.nlm.nih.gov] […] antigen (HLA)-matched donors and decreased application in older patients with significant morbidity.[ncbi.nlm.nih.gov]

  • Severe Aplastic Anemia

    […] transplantation (SCT) can be curative for patients with severe aplastic anemia (SAA). 1 , 2 Concerns about graft failure and graft-versus-host disease (GVHD), more so for human leukocyte[nature.com] In virus-associated hemophagocytic syndrome with an acute parvovirus B19 infection, raised levels of cytokines such as interferon γ would impair regulation of the phagocytic[omicsonline.org] The introduction of post-SCT cyclophosphamide (PTCy) has been shown to decrease alloreactivity in the host-versus-graft and graft-versus-host directions and could be particularly[nature.com]

  • Multicentric Castleman's Disease

    […] lymphoma; HLH-MAS, hemophagocytic lymphohistiocytosis- macrophage activation syndrome; IgG4, IgG4-related disease; JIA, juvenile idiopathic arthritis; M-HLH, malignancy-associated[doi.org] ALPS, autoimmune lymphoproliferative syndrome; AOSD, adult-onset Still disease; EBV, Epstein-Barr virus; FDC, follicular dendritic cell; HHV-8, human herpesvirus-8; HL, Hodgkin[doi.org]

  • Hypersplenism

    As a disorder, hypersplenism typically involves a distended spleen (splenomegaly), decreased levels of leukocytes, erythrocytes and platelets, shorter platelet and erythrocyte[symptoma.com] Case Report. ( 27227931 ) Lu X.X....Zheng S. 2016 21 Severe hypersplenism associated to hemophagocytic and lymphoproliferative syndrome secondary to Epstein-Barr virus infection[malacards.org] , and platelets, resulting in mild-to-moderate decreases in some or all of these cell lines.[emedicine.medscape.com]

  • Dengue Fever

    […] of leukocytes and platelets.[ncbi.nlm.nih.gov] ’s records revealed that she met the clinical case definition for hemophagocytic lymphohistiocytosis, a hyperinflammatory syndrome that is sometimes associated with dengue[emedicine.com] […] bitten by mosquitoes, a 60-year-old Japanese female exhibited positive serologic tests of immunoglobulin M and G enzyme immunoassays for dengue viral infection along with a decrease[ncbi.nlm.nih.gov]

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