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673 Possible Causes for Leukocytosis, Malaise, Splenomegaly

  • Infectious Mononucleosis

    Clinical estimates of splenomegaly are fallible.[ncbi.nlm.nih.gov] Sprunt, Frank Alexander Evans (1889-1956): Mononuclear leukocytosis in reaction to acute infection (infectious mononucleosis).[whonamedit.com] A 16-year-old, previously healthy girl presents with a several-day history of fever, sore throat, and malaise. She appears very tired and has a temperature of 39 C.[oadoi.org]

  • Infective Endocarditis

    This score includes clinical, epidemiological (male, fever, splenomegaly, clubbing, vascular disease and stroke) and biological criteria (Leucocytes 10,000/mm3, sedimentation[ncbi.nlm.nih.gov] CASE PRESENTATION: A 57-year-old white man presented with bilateral large leg ulcers, fever, and marked leukocytosis.[ncbi.nlm.nih.gov] CASE PRESENTATION: A 77-year-old Asian man with a 10-year history of psoriatic erythroderma was referred due to high fever and general malaise.[ncbi.nlm.nih.gov]

  • Leukemia

    Five features were present in 50% of children: hepatomegaly (64%), splenomegaly (61%), pallor (54%), fever (53%) and bruising (52%).[ncbi.nlm.nih.gov] Evaluation Step 0: Leukocytosis ( White Blood Cell Count 11,000/mm3) Confirmed with a second Complete Blood Count with differential No other obvious cause for Leukocytosis[fpnotebook.com] […] fatigue (including ‘malaise’ and ‘malaise/fatigue’) and infections (including ‘infection’ and ‘recurrent infections’).[doi.org]

  • Splenic Infarction

    On admission, he had a low-grade fever and was grossly anaemic; examination revealed splenomegaly.[ncbi.nlm.nih.gov] A post hoc analysis demonstrated that single infarcts were more likely to be associated with fever (20% vs. 63%, p 0.05) and leukocytosis (75% vs. 33%, P 0.06) CONCLUSIONS[ncbi.nlm.nih.gov] Furthermore, constitutional symptoms (fatigue, malaise) and a poor general condition might lead to a state of shock due to severe subcapsular bleeding that may be life-threatening[symptoma.com]

  • Subacute Bacterial Endocarditis

    Fever, anaemia, splenomegaly and positive blood cultures for Gram-negative bacteria were found on admission.[ncbi.nlm.nih.gov] Laboratory studies may show anemia, leukocytosis, elevated erythrocyte sedimentation rate (ESR), and microscopic hematuria.[symptoma.com] Among the signs of subacute bacterial endocarditis are: Malaise Weakness Excessive sweat Fever It is usually caused by a form of Viridans group streptococcus bacteria that[en.wikipedia.org]

  • Chronic Lymphocytic Leukemia

    One month later, he presented with progressive leukocytosis (mostly neutrophilia) and splenomegaly.[ncbi.nlm.nih.gov] The CLL itself leads to unspecific symptoms such as general malaise and weakness, possibly also to fever, night sweats and weight loss.[symptoma.com] BACKGROUND/AIM: In chronic lymphocytic leukemia (CLL) the absolute neutrophil count (ANC) has generally been reported to be within normal limits and leukocytosis is due to[ncbi.nlm.nih.gov]

  • Alcoholic Hepatitis

    Image studies showed an extremely enlarged fatty liver and splenomegaly.[ncbi.nlm.nih.gov] Although a leukocytosis of 15,000-18,000 cells/mm(3) is frequently seen in AH, LRs are rare in this context.[ncbi.nlm.nih.gov] […] circulation Bone Rib fractures on CXR Spinal osteoporosis (particularly in men) Generally, patients with fatty liver have few symptoms, however they may notice nausea and malaise[almostadoctor.co.uk]

  • Acute Myelocytic Leukemia

    Typical symptoms are spongy and bleeding gums, anemia, fatigue, fever, dyspnea, moderate splenomegaly, joint and bone pain, and repeated infections.[medical-dictionary.thefreedictionary.com] Thus, the bone marrow and peripheral blood are characterized by leukocytosis with a predominance of immature cells, primarily blasts.[ncbi.nlm.nih.gov] […] receiving NEUPOGEN It may occur as early as the first week after start of therapy Manifestations may include generalized signs and symptoms such as fever, abdominal pain, malaise[neupogenhcp.com]

  • Malaria

    Abstract We report the case of a 12-year-old child who was admitted to our Department, with 7 days' history of high fever and splenomegaly.[ncbi.nlm.nih.gov] When neutrophil leukocytosis present raises possibility of secondary bacterial infection [ 41 ] Platelets Usually low.[doi.org] The protean and nonspecific clinical findings occurring in malaria (fever, malaise, headache, myalgias, jaundice and sometimes gastrointestinal symptoms of nausea, vomiting[ncbi.nlm.nih.gov]

  • Acute Lymphoblastic Leukemia

    Splenomegaly and thrombocytopenia were frequently observed more in CD200 patients. Increased frequency of CD34 was associated with CD200 and CD56 patients.[ncbi.nlm.nih.gov] , hematological, and immunocytological) parameters pointed towards a diagnosis of Wilms tumor in our case, the subsequent development of thrombocytopenia and lymphocytic leukocytosis[ncbi.nlm.nih.gov] They largely reflect bone marrow failure and include malaise, fatigue, bleeding or bruising, and secondary infections.[accessmedicine.mhmedical.com]

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