1,587 Possible Causes for Leukodystrophy

  • Globoid Cell Leukodystrophy

    Historical note and terminology Globoid cell leukodystrophy, or Krabbe disease, was described in 1916.[medlink.com] Krabbe, Knud Haraldsen, Danish neurologist, 1885-1961. Krabbe disease - a metabolic disorder of infancy.[medical-dictionary.thefreedictionary.com] In the juvenile and adult forms disease may not be as severe, and life expectancy may be improved. How is Krabbe Disease (Globoid cell leukodystrophy) Treated?[myvmc.com]

  • Diffuse Cerebral Sclerosis of Schilder

    Schilder's disease now appears to belong to a heterogeneous group of disorders which includes Krabbe's disease , sudanophilic cerebral sclerosis, metachromatic leukodystrophy[patient.info] The association of adrenoleukodystrophy (sudanophilic leukodystrophy , Schilder's disease, or diffuse cerebral sclerosis) and adrenal insufficiency has been recognized for[researchgate.net] Schilder's disease [ shil derz ] Schilder's disease [shil′dərz] Etymology: Paul F.[medical-dictionary.thefreedictionary.com]

  • Hearing Impairment
  • Deletion of the Long Arm of Chromosome 18

    Beyond this, treatment of 18q-syndrome is supportive, and can alleviate some of the symptoms of the disease. Prognosis is highly varied.[ulf.org] (including clubfoot, short thumbs) Eye movement disorders Genital hypoplasia: incomplete development of the genitals Hypotonia: poor muscle tone Hearing impairment Heart disease[ulf.org] Loss of MBP in mice results abnormalities in myelin formation, supporting the theory that the loss of MBP is at least partly responsible for the leukodystrophy.[ulf.org]

  • Ovarian Dysgenesis

    MRI showed diffuse white matter disease, with frontal cortical atrophy.[pediatricneurologybriefs.com] National Institutes of Neurological Disease, and Child Health and Development, Bethesda, MD.[pediatricneurologybriefs.com] Known causes for leukodystrophy were also excluded. The molecular basis for the syndrome remains to be determined.[pediatricneurologybriefs.com]

  • Kluver-Bucy Syndrome

    Postmortem examination disclosed the characteristic histopathologic changes of adreno-leukodystrophy in the nervous system, adrenal gland, and testis. 1980 by the American[neurology.org]

  • Leukodystrophy

    "Lysosomal leukodystrophies - Krabbe disease and metachromatic leukodystrophy" .[en.wikipedia.org] Examples of lysosomal disorders include metachromatic leukodystrophy, globoid cell leukodystrophy or Krabbe disease, and various mucolipidoses and gangliosidoses.[news-medical.net] Globoid cell leukodystrophy (GLD), also known as Krabbe disease and galactocerebrosidase deficiency, is autosomal recessively inherited, and caused by defects in the glycosylceramidase[encyclopedia.com]

  • Metachromatic Leukodystrophy

    Metachromatic Leukodystrophy Adult Metachromatic Leukodystrophy General Discussion Metachromatic leukodystrophy, the most common form of leukodystrophy, is a rare inherited[webmd.com] Metachromatic leukodystrophy ( MLD , also called arylsulfatase A deficiency ) is a lysosomal storage disease which is commonly listed in the family of leukodystrophies as[en.wikipedia.org] The disease course may be from three to ten or more years in the late-infantile form and up to 20 years or more in the juvenile and adult forms. • Late-infantile MLD .[flipper.diff.org]

  • Familial Osteodysplasia

    Fucosidosis Fukuyama Congential Muscular Dystrophy Galactosialidosis Globoid Cell Leukodystrophy (Krabbe Disease) GM1 Gangliosidosis GM2 Gangliosidosis (Tay-Sachs Disease[ulf.org] (Krabbe Disease) Hereditary Adult Onset Leukodystrophy simulating chronic progressive multiple sclerosis Hypomyelination with Atrophy of the Basal Ganglia and Cerebellum[thejacksonproject.org] Onset Autosomal Dominant Leukodystrophy (ADLD) Adult Polyglucosan Body Disease Aicardi-Goutieres Syndrome Alexander Disease Autosomal Dominant Diffuse Leukoencephalopathy[ulf.org]

  • Dementia

    These include familial Alzheimer's disease , SCA17 ( dominant inheritance); adrenoleukodystrophy ( X-linked ); Gaucher's disease type 3, metachromatic leukodystrophy , Niemann-Pick[en.wikipedia.org] "Cognitive Decline in a Young Adult with Pre-Existent Developmental Delay – What the Adult Neurologist Needs to Know" .[en.wikipedia.org] In young adults (up to 40 years of age) who were previously of normal intelligence, it is very rare to develop dementia without other features of neurological disease, or[en.wikipedia.org]

Further symptoms

Similar symptoms