171 Possible Causes for Leukodystrophy in USA

  • Leukodystrophy

    leukodystrophies. … For three types of leukodystrophies (X-linked adrenoleukodystrophy (X-ALD), metachromatic leukodystrophy (MLD) and Krabbe Disease (globoid cell leukodystrophy - GLD), gene … Leukodystrophy at DMOZ United Leukodystrophy Foundation Leukodystrophy Alliance MLD Foundation - metachromatic leukodsytrophy ALD LIfe - Adrenoleukodsytrophy UK Documentary[1]

  • Metachromatic Leukodystrophy

    There are three subtypes of metachromatic leukodystrophy. … Adult metachromatic leukodystrophy generally presents at 17 years of age or older. … Juvenile metachromatic leukodystrophy commonly occurs between 3 and 16 years of age.[2]

  • Peroxisomal Disease

    United Leukodystrophy Foundation The United Leukodystrophy Foundation is dedicated to helping children and adults who have leukodystrophy and assisting the family members, … Peroxisomal disorders also include: The European Leukodystrophy Foundation The mission of the ELA is to help and support families affected by leukodystrophy, to stimulate … ELA is thus a bridge between all forms of leukodystrophy and a family solidarity network.[3]

  • Canavan Disease

    What Characterizes Leukodystrophies? … Occasionally, the leukodystrophies are misdiagnosed, as Multiple Sclerosis and Cerebral Palsy. … Inheritance of Leukodystrophies Canavan disease is inherited as an autosomal recessive disorder.[4]

  • Refsum Disease

    The most common leukodystrophies include Canavan disease, Krabbe disease, metachromatic Leukodystrophy (MLD), Childhood Ataxia with Central Nervous System Hypomyelination … The leukodystrophies are often referred to as “demyelinating” diseases. … As myelin deteriorates in leukodystrophies such as Refsum disease, nervous system function is impaired.[5]

  • Alexander Disease

    Alexander disease, also known as fibrinoid leukodystrophy, is a progressive and fatal neurodegenerative disease. … Alexander disease belongs to leukodystrophies, a group of diseases that affect the growth or development of the myelin sheath. … A rough diagnosis may also be made through revealing of clinical symptoms including, enlarged head size, along with radiological studies, and negative tests for other leukodystrophies[6]

  • Demyelinating Disease

    adrenoleukodystrophy Krabbe leukodystrophy metachromatic leukodystrophy sometimes classified as leukodystrohpies 2 Alexander disease Canavan disease Cockayne syndrome Pelizaeus-Merzbacher … considered separately but for the sake of completeness they are listed below. central pontine myelinolysis (CPM) posterior reversible encephalopathy syndrome (PRES) chemotherapy leukodystrophies … He noted that imbalances in proteostasis have been reported to contribute to some leukodystrophies.[7] [8]

  • Cerebrotendinous Xanthomatosis

    It falls within a group of genetic disorders called the leukodystrophies.[9]

  • Globoid Cell Leukodystrophy

    Globoid cell leukodystrophy may also be referred to as Krabbe disease. … Globoid cell leukodystrophy (GLC) is a rare genetic disorder. … Globoid cell leukodystrophy is a rare, degenerative disease associated with progressive demyelination; symptom onset typically occurs in infancy.[10]

  • Rieger Syndrome

    , Dysmyelinating, with Oligodontia Leukodystrophy, Hypomyelinating, with Hypodontia and Hypogonadotropic Hypogonadism Leukomelanoderma, Infantilism, Mental Retardation, Hypodontia … bullosa, late-onset localized junctional, with mental retardation Growth Retardation, Alopecia, Pseudoanodontia and Optic Atrophy Hypodontia Oligodontia with Orofacial Cleft Leukodystrophy[11]

Further symptoms

Similar symptoms


  1. Leukodystrophy, https://en.wikipedia.org/wiki/Leukodystrophy
  2. Metachromatic Leukodystrophy, https://www.symptoma.com/en/info/metachromatic-…
  3. Peroxisomal disorder, https://en.wikipedia.org/wiki/Peroxisomal_disorder
  4. Canavan Info | Jacobs Ladder, http://jacobsladder.ca/canavan/
  5. Refsum Disease | National Stem Cell Foundation, http://www.nationalstemcellfoundation.org/refsu…
  6. Alexander disease, https://en.wikipedia.org/wiki/Alexander_disease
  7. Demyelination | Radiology Reference Article, http://radiopaedia.org/articles/demyelination
  8. New drug ‘dials down’ protein synthesis to treat demyelinating diseases, http://www.buffalo.edu/news/releases/2015/04/042.html
  9. Cerebrotendineous xanthomatosis, https://en.wikipedia.org/wiki/Cerebrotendineous…
  10. Globoid Cell Leukodystrophy, https://www.symptoma.com/en/info/globoid-cell-l…
  11. Axenfeld-Rieger Syndrome, Type 2 - Ontology Browser, http://rgd.mcw.edu/rgdweb/ontology/view.html?ac…