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252 Possible Causes for Leukopenia, Normocytic Normochromic Anemia, Thrombocytopenia

  • Paroxysmal Nocturnal Hemoglobinuria

    The combination of thrombosis, splenomegaly, and thrombocytopenia (TST) is challenging because anticoagulants are indicated but thrombocytopenia may increase the bleeding[ncbi.nlm.nih.gov] CBC showed leukopenia (WBC 2.9 x 103 /µL) with neutropenia (segmented neutrophils 48%), macrocytic anemia (Hgb 6.1 g/dL, hematocrit 20%, MCV,113 fL) and thrombocytopenia ([ncbi.nlm.nih.gov] Leukopenia, thrombocytopenia, arterial and venous thromboses, and episodic crises are common. Diagnosis requires flow cytometry.[merckmanuals.com]

  • Familial Myelofibrosis

    Blood counts generally reveal normocytic, normochromic anemia, leukopenia, and thrombocytopenia.[symptoma.com] Blood counts generally reveal normocytic, normochromic anemia, leukopenia, and thrombocytopenia.[symptoma.com] Blood counts generally reveal normocytic, normochromic anemia, leukopenia, and thrombocytopenia.[symptoma.com]

  • Aplastic Anemia

    After the initial appearance of AMI approximately 2 months earlier, he had received conservative treatment/transfusion alone because of severe thrombocytopenia and anemia[ncbi.nlm.nih.gov] The regimen has a low incidence of bone marrow suppression, and the incidences of anemia, leukopenia, neutropenia and thrombocytopenia exceeding grade 3 are less than 5%.[ncbi.nlm.nih.gov] Read More on This Topic blood disease: Normocytic normochromic anemias In aplastic anemia the normally red marrow becomes fatty and yellow and fails to form enough of its[britannica.com]

  • Hairy Cell Leukemia

    We are reporting a 4-year-old child who was received for investigation for persistent anemia, prolonged fever, and thrombocytopenia.[ncbi.nlm.nih.gov] Later he developed leukopenia and pancytopenia. Bone marrow biopsies showed fibrosis.[ncbi.nlm.nih.gov] , normochromic anemia, rarely aplastic anemia due to infiltration of BM, spleen, lymph nodes; 10% have platelet counts of 20 x 109/L–US: 20,000/mm3, 20% have thrombocytosis[medical-dictionary.thefreedictionary.com]

  • Primary Myelofibrosis

    Six weeks later, he developed grade 4 thrombocytopenia and grade 3 anemia.[ncbi.nlm.nih.gov] We found that fibrosis grade 2 and greater on a 0-3 scale was associated with clinical characteristics indicative of a more advanced disease, such as anemia, leukopenia, thrombocytopenia[ncbi.nlm.nih.gov] Normocyticnormochromic anemia is present in most, but not all, patients (see Table 91–2). 7–15,262–265 Mean hemoglobin concentration in a series of patients at diagnosis[patient-help.com]

  • Severe Aplastic Anemia

    She recovered completely, but her thrombocytopenia persisted. Six weeks later she became pancytopenic. A bone marrow aspirate and biopsy showed severe aplastic anemia.[ncbi.nlm.nih.gov] Symptoms result from anemia, thrombocytopenia (petechiae, bleeding), or leukopenia (infections).[msdmanuals.com] Read More on This Topic blood disease: Normocytic normochromic anemias In aplastic anemia the normally red marrow becomes fatty and yellow and fails to form enough of its[britannica.com]

  • Atypical Hemolytic Uremic Syndrome

    A 28-day-old female presented with gross hematuria and hypertension. aHUS was suspected based on anemia with schistocytes, thrombocytopenia, low C3, and acute kidney injury[ncbi.nlm.nih.gov] Biochemistry revealed: normocytic normochromic anemia (Hb 6 g/dL); platelet count 132 10 9 L 1 , acute kidney injury (Urea 81 mmol/L; Creatinine 1487 μmol/L); high Lactate[medintensiva.org] After three doses, the child developed leukopenia (total leukocyte count 3500/mm 3 and absolute neutrophil count 800/mm 3 ).[indianjnephrol.org]

  • Hypersplenism

    The laparoscopic splenic vessels ligation is a feasible option for treating hypersplenism and thrombocytopenia in children.[ncbi.nlm.nih.gov] Unfortunately, these patients may become intolerant to this therapy when it is complicated by hypersplenism with leukopenia and/or thrombocytopenia.[ncbi.nlm.nih.gov] Normocytic, normochromic anemia Reticulocytes increased Increased MCV is due to prominent reticulocytosis Spherocytes Bone marrow Hypercellular with erythroid precursors[5minuteconsult.com]

  • Agranulocytosis

    We describe a second case of fluconazole associated agranulocytosis with thrombocytopenia and recovery upon discontinuation of therapy.[ncbi.nlm.nih.gov] The risks of severe leukopenia and agranulocytosis have varied over time and among geographical regions and cultures, with little information available on South American populations[ncbi.nlm.nih.gov] Peripheral smear showed normocytic normochromic anemia with Rouleaux formation, leucopenia with 2% atypical cells and mild thrombocytosis.[ncbi.nlm.nih.gov]

  • Pancytopenia

    […] mm(3), and severe thrombocytopenia as thrombocyte counts below 20,000/mm(3).[ncbi.nlm.nih.gov] In this study, we describe seven cases of severe thrombocytopenia, anemia and leukopenia (pancytopenia) from the same geographic locality and similar clinical presentation[ncbi.nlm.nih.gov] Anemias were then classified morphologically into four groups - normocytic normochromic, microcytic hypochromic, macrocytic, and dimorphic.[mjdrdypu.org]

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