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314 Possible Causes for Leukopenia, Normocytic Normochromic Anemia, Thrombocytopenia

  • Paroxysmal Nocturnal Hemoglobinuria

    This case raises caution for heparin-induced thrombocytopenia in paroxysmal nocturnal hemoglobinuria.[ncbi.nlm.nih.gov] CBC showed leukopenia (WBC 2.9 x 103 /µL) with neutropenia (segmented neutrophils 48%), macrocytic anemia (Hgb 6.1 g/dL, hematocrit 20%, MCV,113 fL) and thrombocytopenia ([ncbi.nlm.nih.gov] Leukopenia, thrombocytopenia, arterial and venous thromboses, and episodic crises are common. Diagnosis requires flow cytometry.[merckmanuals.com]

  • Anorexia Nervosa

    Many hematologic abnormalities (anaemia, leukopenia and thrombocytopenia) were present and worsened during the occurrence of sepsis which required hemotransfusions and targeted[ncbi.nlm.nih.gov] Laboratory work-up revealed markedly elevated LFTs, hypoglycemia, thrombocytopenia and elevated INR and lipase. ECG showed sinus bradycardia with prolonged QTc.[ncbi.nlm.nih.gov] Leukopenia is frequently observed in patients with anorexia nervosa (AN). However, serious infectious diseases are infrequent in patients with AN.[ncbi.nlm.nih.gov]

  • Familial Myelofibrosis

    Blood counts generally reveal normocytic, normochromic anemia, leukopenia, and thrombocytopenia.[symptoma.com] , thrombocytosis, increased LDH Prognostic factors Histologic stage at diagnosis (prefibrotic versus fibrotic) Adverse factors include age 70 years, anemia (Hb 10 g/dL), thrombocytopenia[pathologyoutlines.com] Responses were also reported for anaemia (22%) and thrombocytopenia (50%).[onlinelibrary.wiley.com]

  • Aplastic Anemia

    After the initial appearance of AMI approximately 2 months earlier, he had received conservative treatment/transfusion alone because of severe thrombocytopenia and anemia[ncbi.nlm.nih.gov] Symptoms result from anemia, thrombocytopenia (petechiae, bleeding), or leukopenia (infections).[merckmanuals.com] Read More on This Topic blood disease: Normocytic normochromic anemias In aplastic anemia the normally red marrow becomes fatty and yellow and fails to form enough of its[britannica.com]

  • Leukoerythroblastic Anemia

    Acute Erythroblastic Leukemia Anemia, X-Linked, without Thrombocytopenia aplastic anemia Aplastic Anemia, Idiopathic Bone Marrow Failure Syndromes chronic myeloid leukemia[rgd.mcw.edu] Myelophthisic anemia is a normocytic-normochromic anemia that occurs when normal marrow space is infiltrated and replaced by nonhematopoietic or abnormal cells.[merckmanuals.com] Leukopenia ( 4.0 x 10(9)/l leukocytes), thrombocytopenia ( 150 x 10(9)/l Plt), elevated LDH levels ( 220 U/l), and laboratory evidence of disseminated intravascular coagulation[ncbi.nlm.nih.gov]

  • Myelophthisis

    Causes of isolated thrombocytopenia include viral infections, immune-mediated platelet destruction, congenital diseases, gestational thrombocytopenia, conditions in which[consultant360.com] CBC -anemiaHb, HCT -polycythemia -leukocytosis WBC -leukopenia -abnormal cells -thrombocytosisPlatelet -thrombocytopenia 5.[pt.slideshare.net] Myelophthisic anemia is a normocytic-normochromic anemia that occurs when normal marrow space is infiltrated and replaced by nonhematopoietic or abnormal cells.[merck.com]

  • Pancytopenia

    […] mm(3), and severe thrombocytopenia as thrombocyte counts below 20,000/mm(3).[ncbi.nlm.nih.gov] In this study, we describe seven cases of severe thrombocytopenia, anemia and leukopenia (pancytopenia) from the same geographic locality and similar clinical presentation[ncbi.nlm.nih.gov] Our patient’s symptoms, signs, and laboratory values (with normocytic normochromic anemia) are inconsistent with symptomatic colon cancer leading to iron-deficiency anemia[mdedge.com]

  • Ehrlichiosis

    […] year-old boy who was referred to the Hematology-Oncology Clinic to consider a bone marrow etiologic process after his pediatrician discovered progressive neutropenia, anemia, thrombocytopenia[ncbi.nlm.nih.gov] I report a case of tick-borne ehrlichiosis in which the primary presentation suggested an infectious diarrhea, with impressive leukopenia and thrombocytopenia.[ncbi.nlm.nih.gov] During the acute phase of E canis infection in dogs, the hemogram is usually normal but may reflect a mild normocytic, normochromic anemia; leukopenia; or mild leukocytosis[merckmanuals.com]

  • Multiple Myeloma

    KEYWORDS: Multiple myeloma; autoimmun hemolytic anemia; evan s syndrome; thrombocytopenia[ncbi.nlm.nih.gov] This interferes with blood cell production leading to anemia, leukopenia, and thrombocytopenia.[symptoma.com] […] typically normochromic/normocytic renal failure proteinuria hypercalcemia Presentation may also be with a complication, including: pathological fracture vertebral compression[radiopaedia.org]

  • Myelodysplasia

    Neutropenia and thrombocytopenia were the most common treatment-associated adverse events ( Table 4 ).[doi.org] Serum copper determination should be included in the work-up of patients with anemia and leukopenia of unclear etiology who have associated myeloneuropathy.[ncbi.nlm.nih.gov] The anemia was normochromic and normocytic in seven patients. Neutropenia was present in seven patients.[ncbi.nlm.nih.gov]

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