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327 Possible Causes for Leukopenia, Osteopenia and Osteoporosis, Thrombocytopenia

  • Gaucher Disease

    KEYWORDS: GBA gene mutation; Gaucher cells; thrombocytopenia; type 1 Gaucher disease[ncbi.nlm.nih.gov] Spleen enlargement and bone marrow replacement cause anemia, thrombocytopenia, and leukopenia.[en.wikipedia.org] Osteopenia and osteoporosis may not improve, especially in elderly patients, and new sporadic episodes of osteonecrosis and fracture may occur, especially in patients with[bloodjournal.org]

  • Leukemia

    CASE PRESENTATION: We report a case of a 53 year old patient with T-LGL, Immune-Thrombocytopenia (ITP) and combined antibody deficiency, who presented with fever and reduced[ncbi.nlm.nih.gov] Common side effects of Besponsa include low levels of platelets (thrombocytopenia), low levels of certain white blood cells (neutropenia, leukopenia), infection, low levels[fda.gov] Bone damage – Chemotherapy or corticosteroid treatment can lead to osteopenia and osteoporosis – signs of decreased bone density, increasing the risk of fractures.[hopkinsmedicine.org]

  • Systemic Mastocytosis

    Abstract An elderly woman presented with anaemia, thrombocytopenia and multifocal lytic and sclerotic bone lesions.[ncbi.nlm.nih.gov] However, as has been indicated above, leukopenia and thrombocytosis have also been detected in cases of SM and should therefore not be considered exclusion criteria.[symptoma.com] Bone manifestations of SM include: osteopenia with or without lytic lesions, osteoporosis with or without atraumatic fracture, osteosclerosis with increased bone density,[ncbi.nlm.nih.gov]

  • Felty's Syndrome

    She had had a previous splenectomy for symptomatic thrombocytopenia, having received pneumococcal vaccine before the operation.[ncbi.nlm.nih.gov] Jump to navigation Jump to search syndrome that results in rheumatoid arthritis, splenomegaly and neutropenia Felty syndrome Rheumatoid arthritis with splenoadenomegaly and leukopenia[wikidata.org] […] and osteopenia secondary to steroid use, inactivity, and disease process bisphosphantes is an effective prophylactic therapy in these patients Nephrotic syndrome result of[medbullets.com]

  • Multiple Myeloma

    Moreover, there was much more largely decreased incidence of grade 3 and higher thrombocytopenia and BIPN in bortezomib SC administration than IV route.[ncbi.nlm.nih.gov] This interferes with blood cell production leading to anemia, leukopenia, and thrombocytopenia.[symptoma.com] Bisphosphonates (alendronate or zoledronic acid) have been shown to improve bone mineral density in MGUS patients with osteopenia/osteoporosis or osteoporotic fractures (grade[doi.org]

  • Systemic Lupus Erythematosus

    Blood platelet counts (BPCs) of 20   10/L represent severe thrombocytopenia, and a BPC of 21 to 50   10/L indicates moderate thrombocytopenia.[ncbi.nlm.nih.gov] Drugs causing leukopenia Some drugs may lead to leukopenia.[news-medical.net] Osteopenia was present in 50.3% of patients and osteoporosis in 17.4%. At least one vertebral fracture was detected in 26.1%.[ncbi.nlm.nih.gov]

  • Primary Myelofibrosis

    Six weeks later, he developed grade 4 thrombocytopenia and grade 3 anemia.[ncbi.nlm.nih.gov] We found that fibrosis grade 2 and greater on a 0-3 scale was associated with clinical characteristics indicative of a more advanced disease, such as anemia, leukopenia, thrombocytopenia[ncbi.nlm.nih.gov] Neither osteoporosis nor osteopenia were found.[ncbi.nlm.nih.gov]

  • Propionic Acidemia

    Severe thrombocytopenia is the hallmark of the metabolic crisis.[ncbi.nlm.nih.gov] […] propionyl-CoA carboxylase deficiency glycinemia, ketotic ketotic hyperglycinemia PROP Propionicacidemia PROPIONIC ACIDEMIA Pcc Deficiency Hyperglycinemia With Ketoacidosis and Leukopenia[wikidata.org] Osteoporosis or osteopenia have only been documented in one patient.[flipper.diff.org]

  • Acute Lymphoblastic Leukemia

    This bleeding is commonly attributed to thrombocytopenia due to bone marrow suppressive chemotherapeutic agents.[ncbi.nlm.nih.gov] CASE REPORT We report the case of a 58-year-old male patient who presented with severe chest pain, dyspnea, systemic symptoms, leukopenia, normocytic anemia, and severe lactic[ncbi.nlm.nih.gov] Another great burden of treatment is the current high frequency of avascular necrosis and osteoporosis/osteopenia from high doses of corticosteroids that develops in higher[clinicaladvisor.com]

  • Pegylated Interferon Alfa

    All 12 patients experienced at least one adverse event during treatment: two (17%) patients experienced anaemia, eight (67%) neutropenia, and ten (83%) thrombocytopenia.[ncbi.nlm.nih.gov] Anemia, neutropenia, leukopenia, and thrombcytopenia were 11%, 32%, 52%, and 5%, respectively.[ncbi.nlm.nih.gov] osteoporosis in patients with refractory bone pain and/or worsening bone mineral density on bisphosphonate therapy Use with Ribavirin may cause birth defects and death of[aetna.com]

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