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236 Possible Causes for Leukopenia, Reticulocytes Increased

  • Primary Myelofibrosis

    The percentage of reticulocytes is mildly increased but may vary widely in a given case.[patient-help.com] We found that fibrosis grade 2 and greater on a 0-3 scale was associated with clinical characteristics indicative of a more advanced disease, such as anemia, leukopenia, thrombocytopenia[ncbi.nlm.nih.gov] Compared with pre-PMF, overt PMF was enriched in patients with anemia, thrombocytopenia, leukopenia, higher blast count, symptoms, large splenomegaly, and unfavorable karyotype[ncbi.nlm.nih.gov]

  • Paroxysmal Nocturnal Hemoglobinuria

    CBC showed leukopenia (WBC 2.9 x 103 /µL) with neutropenia (segmented neutrophils 48%), macrocytic anemia (Hgb 6.1 g/dL, hematocrit 20%, MCV,113 fL) and thrombocytopenia ([ncbi.nlm.nih.gov] Erythrocytes fractionated by centrifugation revealed increased glycolytic enzyme activities of hexokinase, G3PD, PGK, TPI, PK, LDH, G6PD, and 6PGD in the reticulocyte-rich[pediatrics.aappublications.org] Leukopenia, thrombocytopenia, arterial and venous thromboses, and episodic crises are common. Diagnosis requires flow cytometry.[merckmanuals.com]

  • Viral Hepatitis

    Fever, nausea, vomiting, abdominal pain, leukopenia, thrombocytopenia, coagulopathy, and a marked rise in serum transaminase levels are invariably present.[ncbi.nlm.nih.gov] […] autopsy due to nonspecific clinical features Better survival in children than adults ( J Hepatol 2011;55:1222 ) Laboratory Sudden, marked elevation of ALT or AST, fever, leukopenia[pathologyoutlines.com] […] immunohistochemical analysis of liver tissue ( Liver Transpl 2007;13:1428 ) Laboratory Marked elevation of liver serum markers (AST, ALT, bilirubin, alkaline phosphatase, GGT) Leukopenia[pathologyoutlines.com]

  • Familial Myelofibrosis

    Blood counts generally reveal normocytic, normochromic anemia, leukopenia, and thrombocytopenia.[symptoma.com] At the same time, the number of immature cells in peripheral blood is increased.[symptoma.com] Thus, patients suffering from myelofibrosis eventually develop anemia, leukopenia, and thrombocytopenia.[symptoma.com]

  • Hypersplenism

    Unfortunately, these patients may become intolerant to this therapy when it is complicated by hypersplenism with leukopenia and/or thrombocytopenia.[ncbi.nlm.nih.gov] Normocytic, normochromic anemia Reticulocytes increased Increased MCV is due to prominent reticulocytosis Spherocytes Bone marrow Hypercellular with erythroid precursors[5minuteconsult.com] A big spleen can cause anaemia, thrombocytopenia and/or leukopenia just by being that massive.[medicguide.blogspot.com]

  • Gaucher Disease

    We report here the case of a young woman with hepatosplenomegaly, leukopenia, and thrombocytopenia.[ncbi.nlm.nih.gov] Spleen enlargement and bone marrow replacement cause anemia, thrombocytopenia, and leukopenia.[en.wikipedia.org] Splenectomy may be helpful for patients with anemia, leukopenia, or thrombocytopenia or when spleen size causes discomfort.[merckmanuals.com]

  • Malaria

    OBJECTIVE: Anemia, Leukopenia, and thrombocytopenia are commonly observed hematological abnormalities in malaria and typhoid patients.[ncbi.nlm.nih.gov] 48 hours or a dose of mefloquine in preceding 12 hours Primaquine phosphate Severe intravascular hemolysis in people with G6PD deficiency, gastrointestinal disturbances, leukopenia[msdmanuals.com]

  • Acute Arsenic Poisoning

    ) and easy bruising / petechia (thrombocytopenia) Anemia and leukopenia are common in chronic arsenic toxicity, are often accompanied by thrombocytopenia and mild eosinophilia[pathologyoutlines.com] Leukocytosis acutely followed by leukopenia and thrombocytopenia may occur.[calpoison.org] , may initially manifest as pancytopenia and be reversible; may have nonspecific clinical presentation of pancytopenia, fatigue / weakness (anemia), frequent infections (leukopenia[pathologyoutlines.com]

  • Anemia

    There may be leukopenia and/or and thrombocytopenia, but these features do not represent a diagnostic requirement.[atlasgeneticsoncology.org] With regenerative anemia, the bone marrow responds appropriately to the decreased red cell mass by increasing RBC production and releasing reticulocytes.[merckvetmanual.com] ., café-au-lait spots; microsomy; low birth weight; thumb, renal, skeletal, and eye abnormalities) Microcytic anemia and reticulocytopenia, thrombocytopenia, or leukopenia[aafp.org]

  • Chronic Malaria

    Abstract The effect of parasitic infections on immunoregulatory T lymphocytes was evaluated by means of quantitative determinations of total T cell and T-cell subset populations present in peripheral blood of patients with lymphatic filariasis, with the malaria-induced tropical splenomegaly syndrome (TSS), and with[…][ncbi.nlm.nih.gov]

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