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683 Possible Causes for Leukopenia, Splenomegaly, Thrombocytopenia

  • Infectious Mononucleosis

    Corticosteroids may have a role in hastening resolution of some complications, especially upper airway obstruction and possibly immune-mediated anemia and thrombocytopenia[dx.doi.org] Leukopenia and thrombocytopenia are not uncommon.[ncbi.nlm.nih.gov] Clinical estimates of splenomegaly are fallible.[ncbi.nlm.nih.gov]

  • Primary Myelofibrosis

    Six weeks later, he developed grade 4 thrombocytopenia and grade 3 anemia.[ncbi.nlm.nih.gov] We found that fibrosis grade 2 and greater on a 0-3 scale was associated with clinical characteristics indicative of a more advanced disease, such as anemia, leukopenia, thrombocytopenia[ncbi.nlm.nih.gov] Abstract We report a patient with very advanced myelofibrosis and huge splenomegaly who showed a complete hematological response to low dose thalidomide with reversal of splenomegaly[ncbi.nlm.nih.gov]

  • Myelodysplasia

    Therapy with granulocyte-colony stimulating factor (G-CSF) and granulocyte-monocyte-colony stimulating factor (GM-CSF) caused splenomegaly and severe thrombocytopenia, which[ncbi.nlm.nih.gov] Serum copper determination should be included in the work-up of patients with anemia and leukopenia of unclear etiology who have associated myeloneuropathy.[ncbi.nlm.nih.gov] Non-reportable disorder s include: Anemia, leukopenia and thrombocytopenia.[seer.cancer.gov]

  • Gaucher Disease

    KEYWORDS: GBA gene mutation; Gaucher cells; thrombocytopenia; type 1 Gaucher disease[ncbi.nlm.nih.gov] Spleen enlargement and bone marrow replacement cause anemia, thrombocytopenia, and leukopenia.[en.wikipedia.org] CONCLUSION: HALS for GD patients with refractory hypersplenism and massive splenomegaly is safe and feasible in experienced hands.[ncbi.nlm.nih.gov]

  • Felty's Syndrome

    She had had a previous splenectomy for symptomatic thrombocytopenia, having received pneumococcal vaccine before the operation.[ncbi.nlm.nih.gov] Jump to navigation Jump to search syndrome that results in rheumatoid arthritis, splenomegaly and neutropenia Felty syndrome Rheumatoid arthritis with splenoadenomegaly and leukopenia[wikidata.org] Computed tomography of the pelvis led to an incorrect diagnosis of malignancy, while radionuclide imaging using Tc-99m sulfur colloid confirmed the diagnosis of ectopic splenomegaly[ncbi.nlm.nih.gov]

  • Systemic Lupus Erythematosus

    Blood platelet counts (BPCs) of 20   10/L represent severe thrombocytopenia, and a BPC of 21 to 50   10/L indicates moderate thrombocytopenia.[ncbi.nlm.nih.gov] Drugs causing leukopenia Some drugs may lead to leukopenia.[news-medical.net] […] relapsing illness, with a variety of different presentations. [ 5 , 6 ] Symptoms and signs are often nonspecific - eg, fatigue (can be severe and debilitating), malaise, fever, splenomegaly[patient.info]

  • Pernicious Anemia

    This is the second description of pernicious anemia associated with autoimmune thrombocytopenia.[ncbi.nlm.nih.gov] A deficiency of white blood cells ( leukopenia ) and platelets ( thrombocytopenia ) in the blood may occur.[britannica.com] Some people with Pernicious Anemia may have an abnormally enlarged liver (hepatomegaly) or spleen (splenomegaly).[rarediseases.org]

  • Paroxysmal Nocturnal Hemoglobinuria

    The combination of thrombosis, splenomegaly, and thrombocytopenia (TST) is challenging because anticoagulants are indicated but thrombocytopenia may increase the bleeding[ncbi.nlm.nih.gov] CBC showed leukopenia (WBC 2.9 x 103 /µL) with neutropenia (segmented neutrophils 48%), macrocytic anemia (Hgb 6.1 g/dL, hematocrit 20%, MCV,113 fL) and thrombocytopenia ([ncbi.nlm.nih.gov] […] response to the action of complement, by acute episodes of hemolysis especially at night with hemoglobinuria noted upon urination after awakening, venous occlusion, and often leukopenia[merriam-webster.com]

  • Ehrlichiosis

    […] year-old boy who was referred to the Hematology-Oncology Clinic to consider a bone marrow etiologic process after his pediatrician discovered progressive neutropenia, anemia, thrombocytopenia[ncbi.nlm.nih.gov] Abstract I report a case of tick-borne ehrlichiosis in which the primary presentation suggested an infectious diarrhea, with impressive leukopenia and thrombocytopenia.[ncbi.nlm.nih.gov] Splenomegaly, a characteristic feature of E. muris infection, was associated with an expanded and disorganized marginal zone and a nearly 66-fold increase in the level of[ncbi.nlm.nih.gov]

  • Post-Polycythemia Vera Myelofibrosis

    KEYWORDS: JAK2 exon 12 mutation; myelofibrosis; polycythemia vera; ruxolitinib; thrombocytopenia[ncbi.nlm.nih.gov] Later he developed leukopenia and pancytopenia. Bone marrow biopsies showed fibrosis.[duo.uio.no] KEYWORDS: myelofibrosis; ruxolitinib; splenomegaly; tumor lysis syndrome[ncbi.nlm.nih.gov]

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