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1,048 Possible Causes for Leukopenia, Splenomegaly, Thrombocytopenia

  • Infectious Mononucleosis

    A 49-year-old man with diabetic mellitus suffered from IM with fever, pharyngitis, parotiditis with lymphadenopathies, thrombocytopenia and splenomegaly.[ncbi.nlm.nih.gov] Clinical estimates of splenomegaly are fallible.[ncbi.nlm.nih.gov] Leukopenia and thrombocytopenia are not uncommon.[ncbi.nlm.nih.gov]

  • Paroxysmal Nocturnal Hemoglobinuria

    The combination of thrombosis, splenomegaly, and thrombocytopenia (TST) is challenging because anticoagulants are indicated but thrombocytopenia may increase the bleeding[ncbi.nlm.nih.gov] CBC showed leukopenia (WBC 2.9 x 103 /µL) with neutropenia (segmented neutrophils 48%), macrocytic anemia (Hgb 6.1 g/dL, hematocrit 20%, MCV,113 fL) and thrombocytopenia ([ncbi.nlm.nih.gov] Leukopenia, thrombocytopenia, arterial and venous thromboses, and episodic crises are common. Diagnosis requires flow cytometry.[merckmanuals.com]

  • Felty's Syndrome

    She had had a previous splenectomy for symptomatic thrombocytopenia, having received pneumococcal vaccine before the operation.[ncbi.nlm.nih.gov] Computed tomography of the pelvis led to an incorrect diagnosis of malignancy, while radionuclide imaging using Tc-99m sulfur colloid confirmed the diagnosis of ectopic splenomegaly[ncbi.nlm.nih.gov] […] of other known causes of leukopenia.[ncbi.nlm.nih.gov]

  • Malignant Histiocytosis

    The terminal event was characterized by fever, hepatosplenomegaly, thrombocytopenia, and a leukemic blood picture.[ncbi.nlm.nih.gov] The long duration of massive splenomegaly suggests that this patient could represent a chronic form of MH.[ncbi.nlm.nih.gov] Two years later, he manifested persistent fever, leukopenia, effusions and hypoproteinemia, and his general condition worsened progressively.[ncbi.nlm.nih.gov]

  • Ehrlichiosis

    […] year-old boy who was referred to the Hematology-Oncology Clinic to consider a bone marrow etiologic process after his pediatrician discovered progressive neutropenia, anemia, thrombocytopenia[ncbi.nlm.nih.gov] Splenomegaly, a characteristic feature of E. muris infection, was associated with an expanded and disorganized marginal zone and a nearly 66-fold increase in the level of[ncbi.nlm.nih.gov] I report a case of tick-borne ehrlichiosis in which the primary presentation suggested an infectious diarrhea, with impressive leukopenia and thrombocytopenia.[ncbi.nlm.nih.gov]

  • Chronic Myelomonocytic Leukemia

    The aim of our study was to analyze the association of immune thrombocytopenia (ITP) with chronic myelomonocytic leukemia (CMML).[ncbi.nlm.nih.gov] Splenomegaly is frequently seen and may be massive.[ncbi.nlm.nih.gov] Not having enough normal white blood cells (leukopenia) can lead to frequent or severe infections .[cancer.org]

  • Hairy Cell Leukemia

    We are reporting a 4-year-old child who was received for investigation for persistent anemia, prolonged fever, and thrombocytopenia.[ncbi.nlm.nih.gov] Also these cytokines may play a role in the development of hairy cell leukemia.Key words: hairy cell leukemia -  sarcoidosis - massive splenomegaly.[ncbi.nlm.nih.gov] Later he developed leukopenia and pancytopenia. Bone marrow biopsies showed fibrosis.[ncbi.nlm.nih.gov]

  • Malaria

    […] describ the case of a young soldier who, after returning from Central Africa, presented a fever associated with petechial purpura and gingivorrhagia, hemogram showed deep thrombocytopenia[ncbi.nlm.nih.gov] Anemia, Leukopenia, and thrombocytopenia are commonly observed hematological abnormalities in malaria and typhoid patients.[ncbi.nlm.nih.gov] We report the case of a 12-year-old child who was admitted to our Department, with 7 days' history of high fever and splenomegaly.[ncbi.nlm.nih.gov]

  • Plasmodium Falciparum Malaria

    Statistics from Altmetric.com Plasmodium falciparum malaria thrombocytopenia traveller Thrombocytopenia is frequent in patients with acute malaria and is sometimes profound[adc.bmj.com] Two black African immigrants, with no history of recent travel outside France, received a diagnosis of a malignant lymphoproliferative disorder and splenomegaly, and they[ncbi.nlm.nih.gov] Fever (100%), splenomegaly (86.7%), hepatomegaly (26.7%), leukopenia (13.3%), thrombocytopenia (80%), elevated liver function tests (40%), and increased serum creatinine levels[ncbi.nlm.nih.gov]

  • Aggressive Systemic Mastocytosis

    A rapidly progressive anemia and thrombocytopenia dictated a splenectomy.[ncbi.nlm.nih.gov] In fact, bone marrow failure is associated with cytopenias and patients suffering from anemia, leukopenia, or thrombocytopenia may present with pallor, weakness, and fatigue[symptoma.com] A 43 year-old woman presented with fever, abdominal pain, epato-splenomegaly, ascites, cholestasis, anemia, thrombocytopenia and previous diagnosis of sclerosing cholangitis[ncbi.nlm.nih.gov]

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