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316 Possible Causes for Leukopenia, Thrombocytopenia, Uric Acid Increased

  • Chemotherapy

    The main outcomes were improvement in chemotherapy-induced grade 3/4 marrow suppression (leukopenia, neutropenia, anemia, and thrombocytopenia) or gastrointestinal toxicities[ncbi.nlm.nih.gov] The patient presented with abdominal pain, haematochezia, acute anaemia and thrombocytopenia. CT of the abdomen and pelvis revealed SISBH.[ncbi.nlm.nih.gov] Hematological toxicities of Grade 3/4 were leukopenia 50%, neutropenia 68%, and febrile neutropenia 18%.[ncbi.nlm.nih.gov]

  • Pernicious Anemia

    This is the second description of pernicious anemia associated with autoimmune thrombocytopenia.[ncbi.nlm.nih.gov] A deficiency of white blood cells ( leukopenia ) and platelets ( thrombocytopenia ) in the blood may occur.[britannica.com] Intravenous Lipid Emulsion-Associated Catatonia, Thrombocytopenia, and Leukopenia: A Case Report and the Role of NMDA Receptor .[bjp.rcpsych.org]

  • Acute Lymphoblastic Leukemia

    This bleeding is commonly attributed to thrombocytopenia due to bone marrow suppressive chemotherapeutic agents.[ncbi.nlm.nih.gov] CASE REPORT We report the case of a 58-year-old male patient who presented with severe chest pain, dyspnea, systemic symptoms, leukopenia, normocytic anemia, and severe lactic[ncbi.nlm.nih.gov] Sodium bicarbonate may be used to alkalinize the urine to increase uric acid excretion. The dietary restriction of potassium and calcium may also be required.[lecturio.com]

  • Chronic Myeloid Leukemia

    […] without thrombocytopenia (p   0.01).[ncbi.nlm.nih.gov] Leukopenia is a shortage of normal white blood cells. This shortage increases the risk of infections.[cancer.org] Gout – increased cell turnover excess purines broken down to uric acid Increased susceptibility to infections – functional immune cells Shortness of breath/fatigue – anaemia[geekymedics.com]

  • Acute Myelocytic Leukemia

    The clinical presentation was similar in all three, with acute onset of hepatomegaly and thrombocytopenia in the absence of significant transaminasemia or icterus.[ncbi.nlm.nih.gov] After completion of streptozotocin therapy, the patient had progressive leukopenia.[ncbi.nlm.nih.gov] Joint Pain Joint pain occurs due to the presence of increased deposition of uric acid in the joints resulting in gout .[lecturio.com]

  • Leukemia

    Patients with the BRAF V600E mutation had a significantly higher frequency of neutropenia, thrombocytopenia, and elevated soluble interleukin-2 receptor and common B-cell[ncbi.nlm.nih.gov] Common side effects of Besponsa include low levels of platelets (thrombocytopenia), low levels of certain white blood cells (neutropenia, leukopenia), infection, low levels[fda.gov] acid. 21 Immunosuppression from chemotherapy, hematopoietic stem cell transplantation, or the leukemia itself may increase the risk of serious infections.[aafp.org]

  • Ifosfamide

    Grade 3 hematological toxicities included neutropenia (34 %), anemia (59 %), and thrombocytopenia (31 %).[ncbi.nlm.nih.gov] We have also observed an association between severe post-treatment leukopenia and the development of IIE, which has not been reported previously.[ncbi.nlm.nih.gov] Hepatic enzymes, uric acid: increased levels Platelets, white blood cells: decreased counts Patient monitoring • Monitor hematopoietic function tests (such as CBC with white[medical-dictionary.thefreedictionary.com]

  • Multiple Myeloma

    Moreover, there was much more largely decreased incidence of grade 3 and higher thrombocytopenia and BIPN in bortezomib SC administration than IV route.[ncbi.nlm.nih.gov] This interferes with blood cell production leading to anemia, leukopenia, and thrombocytopenia.[symptoma.com] acid levels may be elevated as a complication of multiple myeloma.[labtestsonline.org]

  • Sickle Cell Disease

    Patients should be monitored for leukopenia and thrombocytopenia. Complications from long-term usage are not yet known. Efficacy in children has not been proven.[symptoma.com] […] baseline counts may safely tolerate absolute neutrophil counts as low as 1,205 per μL (1.2 10 9 per L) Maintain platelet count 80,000 per μL (80.0 10 9 per L) If neutropenia or thrombocytopenia[aafp.org] ., thrombocytopenia or neutropenia). It is important to monitor blood counts serially while the patient is on therapy, especially during intercurrent illnesses.[clinicaladvisor.com]

  • Hepatosplenomegaly

    In the first 2 days of life, the infant developed hepatosplenomegaly, conjugated hyperbilirubinemia, thrombocytopenia, and hemolysis.[ncbi.nlm.nih.gov] Bacterial sepsis can present with leukopenia or leukocytosis, although I find that leukopenia is both more common and a graver prognostic sign in infants than in older children[jamanetwork.com] From 6 months of age he has had lymphadenopathy, low levels of serum uric acid, increased levels of serum lactate dehydrogenase and hyper gamma-globulinemia.[ncbi.nlm.nih.gov]

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