82 Possible Causes for Leukostasis

  • Chronic Phase of Chronic Myeloid Leukemia

    Rarely, the aforementioned hematological disturbances manifest in dyspnea, transient ischemic attacks, or cerebrovascular accidents (related to leukostasis), gastrointestinal[symptoma.com]

  • Blast Phase

    Hyperleukocytic leukemias and leukostasis: a review of pathophysiology, clinical presentation and management. Leuk Lymphoma. 2000; 39: 1-18 PMID: 10975379 Shet AS et al.[coreem.net] Blast Crisis: A critical increase in circulating leukocytes, or leukostasis, leads to blood hyperviscosity and ultimately decreased tissue perfusion via the formation of white[coreem.net] Leukostasis is generally defined as a leukocytosis greater than 50 x 10 9 /L or 100 x 10 9 /L Clinical Presentation The majority of patients in blast crisis will often present[coreem.net]

  • Promyelocytic Leukemia

    […] cytokine release à capillary leak Treatment: dexamethasone (without treatment, mortality 30%) Role of prophylactic steroids prior to ATRA induction unclear Hyperleukocytosis/leukostasis[errolozdalga.com] Hyperleucocytosis • Marked increase in WBC count due to the rapid maturation induced by ATRA of a large mass of leukemic cells, may result in leukostasis. • Most current remission[slideshare.net] The marked increase in WBC count due to the rapid maturation induced by ATRA of a large mass of leukemic cells, may result in leukostasis and management is controversial.[mjhid.org]

  • Acute Myelocytic Leukemia

    Leukostasis is a medical emergency that calls for immediate intervention.[emedicine.medscape.com] In the case of hyperleukocytosis ( 100 x 109/l), symptoms of leukostasis may manifest. Such symptoms comprise ocular and cerebrovascular hemorrhages and dysfunction.[symptoma.com] Hyperleukocytosis, leukostasis, or both can cause impairment of blood flow, most often resulting in central nervous system (CNS) or pulmonary symptoms.[clevelandclinicmeded.com]

  • Chronic Myeloid Leukemia

    Physical findings of leukostasis and hyperviscosity can occur in some patients, with extraordinary elevation of their WBC counts, exceeding 300,000-600,000 cells/μL.[emedicine.medscape.com]

  • Acute Lymphoblastic Leukemia

    Although patients may present with symptoms of leukostasis (eg, respiratory distress, altered mental status) because of the presence of large numbers of lymphoblasts in the[emedicine.medscape.com] […] leukemia/lymphoma (T-ALL) Bone pain (can be severe and often atypical) Left upper quadrant fullness and early satiety due to splenomegaly (about 10% of cases) Symptoms of leukostasis[emedicine.medscape.com] […] peripheral circulation, leukostasis is much less common in people with ALL than those with acute myelogenous leukemia (AML), and it occurs only in patients with the highest[emedicine.medscape.com]

  • Acute Monocytic Leukemia

    Leukostasis in AML Thornton, KA, Levis, M. FLT3 Mutation and Acute Myelogenous Leukemia with Leukostasis. N Engl J Med 2007; 357:1639.[slideshare.net] Creutzig U, Ritter J, Budde M, et al: Early deaths due to hemorrhage and leukostasis in childhood acute myelogenous leukemia.[jco.ascopubs.org] Leukostasis is a medical emergency that requires immediate intervention. There can also be bone pain.[patient.info]

  • Leukemia
  • Philadelphia Chromosome Positive Chronic Myeloid Leukemia
  • Leukostasis

    leukostasis leu·ko·sta·sis (loo″ko-staґsis) increased blood viscosity and hypercoagulability, seen in leukemia that is accompanied by hyperleukocytosis.[medicine.academic.ru] "Hyperleukocytosis and Leukostasis" . UpToDate .[en.wikipedia.org] AML: Hyperleukocytosis in 10-20 percent of patients, leukostasis more common with WBC 100 X 10 9 cells ALL: Hyperleukocytosis in 10-30 percent of patients, leukostasis very[learnpicu.com]

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