Leukostasis is an extreme form of leukocytosis (an excess of white blood cells) that is dangerously symptomatic. … Leukostasis is different from leukemic infiltration which is a neoplastic process where leukemic cells invade organs.
Chronic myeloid leukemia (CML), also known as chronic myelogenous leukemia, is the most common myeloproliferative disorder.
Most of patients with chronic myelogenous leukemia are diagnosed in the chronic phase and then progress to the accelerated and blast phases in 3 to 5 years. The diagnosis of chronic myeloid…
Promyelocytic leukemia (PL) is a hematopoietic malignancy and more specifically a type of acute myelogenous leukemia (AML), which is characterized by the increased levels of promyelocytes. Promyelocytes are partly differentiated granulocytes, which develop from a myeloblast into the final, completely differentiated…
Acute lymphocytic leukemia (ALL), otherwise referred to as acute lymphoblastic leukemia or acute lymphoid leukemia, is a hematopoietic malignancy that involves the overproduction of cancerous white blood cells in the bone marrow.
Acute lymphoblastic leukemia is a type of malignancy that most commonly affects children.…
Acute monocytic leukemia (AMoL, or AML-M5) is considered a type of acute myeloid leukemia.
In order to fulfill World Health Organization (WHO) criteria for AML-5, a patient must have greater than 20% blasts in the bone marrow, and of these, greater than 80% must be of the monocytic lineage. A further…
Philadelphia chromosome–positive chronic myeloid leukemia (Ph+ CML) is a myeloproliferative disorder in which early progenitor cells undergo malignant transformation. The pathogenesis of this disease is attributed to the presence of the Philadelphia chromosome, which is the result of a reciprocal translocation between…