24 Possible Causes for Leukostasis in USA

  • Leukostasis

    Concepts Disease or Syndrome ( T047 ) MSH D018921 SnomedCT 30419000 English Leukostases , Leukostasis , Leukostasis Syndrome , Leukostasis Syndromes , Syndrome, Leukostasis … , Syndromes, Leukostasis , Leukostasis [Disease/Finding] , Leukostasis syndrome , Leukostasis (morphologic abnormality) Swedish Leukostas Czech leukostáza , Syndrom leukostázy … Leukostasis is typically detected in the brain and lungs of persons with leukemia.[1]

  • Acute Myelocytic Leukemia
    Leukostasis

    Leukostasis is a medical emergency that calls for immediate intervention. … Patients with markedly elevated WBC counts ( 100,000 cells/µL) can present with symptoms of leukostasis (ie, respiratory distress and altered mental status). … In the case of hyperleukocytosis (>100 x 109/l), symptoms of leukostasis may manifest.[2] [3]

  • Acute Monocytic Leukemia
    Leukostasis

    Leukostasis in AML Thornton, KA, Levis, M. … FLT3 Mutation and Acute Myelogenous Leukemia with Leukostasis. … Leukostasis Leukostasis – predominantly in those with WBC counts 100,000 (10% of patients); can also be seen in patients with WBC 50,000 Most common in those with M4 or M5[4]

  • Acute Lymphoblastic Leukemia
    Leukostasis

    Although patients may present with symptoms of leukostasis (eg, respiratory distress, altered mental status) because of the presence of large numbers of lymphoblasts in the … peripheral circulation, leukostasis is much less common in people with ALL than those with acute myelogenous leukemia (AML), and it occurs only in patients with the highest[5]

  • Typhlitis

    Hypercalcemia of malignancy Hyponatremia due to SIADH Adrenal insufficiency Tumor lysis syndrome Carcinoid syndrome Neutropenic fever Neutropenic enterocolitis (typhlitis) Leukostasis[6]

  • Hyperviscosity Syndrome

    Complete blood cell count may show high white blood cell numbers in leukemia and leukostasis.[7]

  • Myeloproliferative Disease

    bruising, bleeding, and/or symptoms of thrombosis Swollen, painful joint(s) secondary to gouty arthritis that is secondary to hyperuricemia Priapism, tinnitus, or stupor from leukostasis … tissue death) of the arms and legs Painful swollen joints, caused by gouty arthritis , which is in turn caused by hyperuricemia Bone pain Priapism Tinnitus Stupor due to leukostasis … Further signs such as tinnitus, priapism, and stupor are suggestive of leukostasis.[8] [9] [10]

  • Promyelocytic Leukemia
    Leukostasis

    cytokine release à capillary leak Treatment: dexamethasone (without treatment, mortality 30%) Role of prophylactic steroids prior to ATRA induction unclear Hyperleukocytosis/leukostasis … Hyperleucocytosis • Marked increase in WBC count due to the rapid maturation induced by ATRA of a large mass of leukemic cells, may result in leukostasis. • Most current remission … The marked increase in WBC count due to the rapid maturation induced by ATRA of a large mass of leukemic cells, may result in leukostasis and management is controversial.[11] [12] [13]

  • Arterial Embolism

    Suspect in patients with heparin exposure, non-severe thrombocytopenia, etc. 3) Hyperviscosity States Waldenstrom’s Macroglobulinemia Leukostasis in the setting of leukemia[14]

  • Arterial Thrombosis

    Suspect in patients with heparin exposure, non-severe thrombocytopenia, etc. 3) Hyperviscosity States Waldenstrom’s Macroglobulinemia Leukostasis in the setting of leukemia[15]

Further symptoms

Similar symptoms

References

  1. Hyperviscosity Syndrome, http://www.fpnotebook.com/HemeOnc/Coags/Hyprvsc…
  2. Acute Myelogenous Leukemia (AML) Clinical Presentation: History, Physical Examination, http://emedicine.medscape.com/article/197802-cl…
  3. Acute Myelocytic Leukemia, https://www.symptoma.com/en/info/acute-myelocyt…
  4. Acute Myeloid Leukemia, http://www.slideshare.net/AALLII/acute-myeloid-leukemia
  5. Acute Lymphoblastic Leukemia (ALL) Clinical Presentation: History, Physical Examination, http://emedicine.medscape.com/article/207631-cl…
  6. Neutropenic enterocolitis (typhlitis) - WikEM, https://wikem.org/wiki/Neutropenic_enterocoliti…
  7. Hyperviscosity Syndrome, https://www.symptoma.com/en/info/hyperviscosity…
  8. Myeloproliferative Disease: Practice Essentials, Background, Pathophysiology, http://emedicine.medscape.com/article/204714-overview
  9. Myeloproliferative Disease, https://www.symptoma.com/en/info/myeloprolifera…
  10. Myeloproliferative Neoplasm - Symptoms and Diagnosis, http://www.diagnose-me.com/symptoms-of/myelopro…
  11. Acute promyelocytic leukemia, http://www.slideshare.net/ranjitapallavi/acute-…
  12. Acute Promyelocytic Leukemia, http://errolozdalga.com/medicine/pages/CW/Acute…
  13. HOW I TREAT NEWLY DIAGNOSED ACUTE PROMYELOCYTIC LEUKEMIA | Avvisati, http://www.mjhid.org/article/view/265/314
  14. Thrombosis/Embolism, Hypercoaguable States & Antiphospholipid Syndrome, http://errolozdalga.com/medicine/pages/Thrombos…
  15. Thrombosis/Embolism, Hypercoaguable States & Antiphospholipid Syndrome, http://errolozdalga.com/medicine/pages/Thrombos…