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90 Possible Causes for Levofloxacin, Sickle Cell Trait

  • Urinary Tract Infection

    […] producing and non-ESBL-producing Escherichia coli in the neutropenic murine complicated urinary tract infection (cUTI) model with humanized exposures of cefepime, ertapenem, and levofloxacin[ncbi.nlm.nih.gov] Nitrofurantoin was the most commonly prescribed drug followed by ciprofloxacin, levofloxacin and amoxicillin clavulanic acid and amikacin.[ncbi.nlm.nih.gov] Four weeks of levofloxacin and minocycline administration successfully eradicated the infection.[ncbi.nlm.nih.gov]

  • Glucose-6-Phosphate Dehydrogenase Deficiency

    Levofloxacin 750 mg orally daily for possible pneumonia, lenalidomide 10 mg orally daily, and dexamethasone 20 mg orally weekly were administered.[ncbi.nlm.nih.gov] Of 1064 couples aged 14-60 years recruited from the Public Health Laboratory, 49 had beta-thalassaemia trait, 69 had sickle-cell trait, 2 had haemoglobin D trait, 2 had haemoglobin[apps.who.int] Sulfasalazine (Azulfidine) Sulfisoxazole (Gantrisin) Nitrofurans Nitrofurantoin (Furadantin, Macrobid, Macrodantin) Quinolones and Fluoroquinolones: Ciprofloxacin (Cipro) Levofloxacin[ihtc.org]

  • Splenic Abscess

    The patient’s creatinine level returned to baseline, his sepsis resolved, and he was discharged home on a 4-week course of levofloxacin.[consultant360.com] Serological evaluation for HIV, amoebiasis, urine culture and screening for sickle-cell trait were all negative. The total leucocyte count was 15 800.[esim.eg.net] Levofloxacin is effective for inflammatory acne and achieves high levels in the lesions: an open study. Dermatology. 2002;204(4):301–2.[link.springer.com]

  • Acute Pyelonephritis

    To compare the efficacy and safety of short-course intravenous levofloxacin (LVFX) 750 mg with a conventional intravenous/oral regimen of LVFX 500 mg in patients from China[ncbi.nlm.nih.gov] Conditions showing renal papillary necrosis: Diabetes mellitus NSAIDs abuse Acute pyelonephritis Sickle cell trait Emphysematous Pyelonephritis In some diabetic patients,[lecturio.com] Levofloxacin Fluoroquinolones (FQ) are the first line empiric treatment for acute pyelonephritis.[hopkinsguides.com]

  • Loss of Vision

    This case report highlights a rare adverse drug reaction caused by levofloxacin, resulting in optic neuritis progressing into unilateral loss of vision.[ncbi.nlm.nih.gov] She had no history of sickle cell disease or trait, diabetes, or coagulopathy. Her visual acuity was 20/200 in the right eye and 20/25 in the left eye.[nejm.org] A 49-year-old male patient was diagnosed to suffer from left maxillary and ethmoid sinusitis and was only prescribed oral levofloxacin 500 mg tablets once daily for 5 days[ncbi.nlm.nih.gov]

  • Rhabdomyolysis

    There are scarce reports in the literature associating rhabdomyolysis to levofloxacin. We describe a case of levofloxacin-induced rhabdomyolysis.[ncbi.nlm.nih.gov] Four out of seven patients tested had sickle cell trait. No alcohol abuse or drug intake was reported, apart from a single reported case of khat ingestion.[ncbi.nlm.nih.gov] To reduce the risk, fitness trainers may want to ask about sickle cell trait (and sickle cell anemia) in their health history questionnaires.[joe-cannon.com]

  • Ureaplasma Infection

    Treatment is with single-dose azithromycin or a week of ofloxacin , levofloxacin , erythromycin , or a tetracycline .[merckmanuals.com] The diagnosis of sickle-cell trait was confirmed with haemoglobin electrophoresis, and an intravenous pyelogram demonstrated the typical medullary cavities seen in this disease[ncbi.nlm.nih.gov] Unfortunately, he was treated by a different doctor with Levofloxacin, which we now know didn't work.[inspire.com]

  • Retroperitoneal Hematoma

    His clinical condition improved after antimicrobial therapy with levofloxacin and rifampin, debridement of the retroperitoneal hematoma and left-side chest tube insertion.[ncbi.nlm.nih.gov] Conditions reported have been included hemophilia, leukemia, polycythemia and sickle cell trait.[e-cmh.org]

  • Red Blood Cell Disorder

    Approximately 4 days after levofloxacin initiation, the man noticed symptoms of fatigue and dizziness.[ucsdlabmed.wikidot.com] A person who has sickle cell trait usually expresses less than 40% HbS , and the client with sickle cell disease may express 85% to 95% HbS .[intranet.tdmu.edu.ua] This is called sickle cell trait (SCT).[cdc.gov]

  • Drug-Induced Autoimmune Hemolytic Anemia

    Drugs that can cause this type of hemolytic anemia include: Cephalosporins (a class of antibiotics) – most common cause [ citation needed ] Dapsone Levodopa Levofloxacin Methyldopa[en.wikipedia.org] Drugs that can cause this type of hemolytic anemia include: Cephalosporins (a class of antibiotics), most common cause Dapsone Levodopa Levofloxacin Methyldopa Nitrofurantoin[medlineplus.gov] The medications known to cause this condition include: cephalosporin antibiotics dapsone levodopa (Parkinson’s disease drug) levofloxacin methyldopa nitrofurantoin nonsteroidal[healthline.com]

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