It can develop into a serious and life-threatening infection. Unfortunately, there is not much known about the condition.
[knowmedge.com]
Complications• Life-threatening infection – ? Increases mortality (36% 5yr)• Splenic rupture• Increased risk of NHL 14.
[fr.slideshare.net]
DMARDs (esp MTX) – Anti-TNF biologics• G-CSF• Anti CD20• Splenectomy “Methotrexate treatment in Feltys syndrome”, Wassenberg et al, Rheum 1998, 37, 8:908-911 10. rG-CSF• For life-threatening
[fr.slideshare.net]