Limb Weakness Causes & Reasons

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Limb Weakness Symptom Checker: Possible causes include Vitamin B12 Deficiency. Check the full list of possible causes and conditions now! Talk to our Chatbot to narrow down your search.

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Patient File

Sex unknown, Age unknown

Reported Symptoms

Limb Weakness,

Negated

None

Unsure

None

Possible Causes

Vitamin B12 Deficiency

This can result in tingling in the feet and hands, weakness in the limbs, and even loss of sensation. [healthyandnaturalworld.com]

A 23-year-old man presented with weakness in the lower limbs, numbness in hands and feet over past 6 months. [ncbi.nlm.nih.gov]

He presented with weakness and numbness of the distal limbs and absent deep tendon reflex in all four extremities. [ncbi.nlm.nih.gov]

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Lumbar Disk Herniation

Weakness of affected limb due to possible nerve compression The above symptoms of Lumbar spondylosis which is predominantly due to vitiated Vata dosha. [bodhiwellnesscentre.com]

We report a 45-year-old male who presented with sudden onset right lower limb weakness after lifting heavy weight. [read.qxmd.com]

In some cases, it can lead to pain, numbness, or weakness in the limbs. However, some people experience no pain, particularly if the disk does not press on any nerves. [medicalnewstoday.com]

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Hypothyroidism

Here we describe a 3-year-old Caucasian girl who was admitted to our Clinic due to pericardial effusion, muscle weakness and weight gain. [ncbi.nlm.nih.gov]

At clinical examination, she presented with bradycardia, pale and round face, pseudohypertrophy of calf muscles and no pitting edema of the limbs. [ncbi.nlm.nih.gov]

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Polymyalgia Rheumatica

Weak or absent pulses may be noticed by the doctor. These symptoms occur in 15% to 20% of patients. What are the symptoms of PMR? [my.clevelandclinic.org]

Weak or absent pulses may be noticed by the doctor. These symptoms occur in 15 to 20% of patients. [my.clevelandclinic.org]

If narrowing occurs in the blood vessels leading to the arms or legs, patients may notice fatigue or aching in the limbs because of a reduced blood supply. [my.clevelandclinic.org]

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Primary Progressive Multiple Sclerosis

The exacerbations manifested as isolated optic neuritis in 9 patients, optic neuritis with limb paresis in 1, isolated diplopia in 2, diplopia with limb weakness in 1, limb [jamanetwork.com]

Symptoms can include: Pain (for example, headaches, pain in the legs and feet, back pain, and muscle spasms) Electric-shock sensations that run down the back and limbs when [hopkinsmedicine.org]

Pyramidal functional system impairment (ie, limb weakness, spasticity, or hyperreflexia) was seen in the following patterns, typically with sparing of the facial musculature [jamanetwork.com]

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Muscular Dystrophy

The symptoms of FSH dystrophy may appear during childhood with severe facial and limb weakness or develop slowly and gradually in adulthood with progressive difficulty closing [kennedykrieger.org]

Later on, after many years, mild limb weakness around the shoulders and hips may also develop. [patient.info]

[…] about Duchenne muscular dystrophy Facioscapulohumeral Muscular Dystrophy: Facioscapulohumeral (FSH) dystrophy is a common muscular dystrophy in which there is progressive weakness [kennedykrieger.org]

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Duchenne Muscular Dystrophy

And 2) are these gait deviations related to lower limb weakness? [ncbi.nlm.nih.gov]

Abstract Duchenne muscular dystrophy (DMD) is an X-linked form of muscular dystrophy characterized by progressive limb-girdle distribution of muscle weakness. [ncbi.nlm.nih.gov]

DMD typically appears between the ages of two with weakness in the pelvis and upper limbs, resulting in clumsiness, frequent falling, an unusual gait and general weakness. [medterms.com]

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Multifocal Motor Neuropathy

The initial high-dose intravenous immunoglobulin treatment significantly improved left upper limb muscle weakness. [ncbi.nlm.nih.gov]

Multifocal motor neuropathy is a disorder characterized by slowly progressive asymmetrical limb weakness and multiple motor conduction blocks. [ncbi.nlm.nih.gov]

Multifocal motor neuropathy (MMN) is typically associated with distal upper limb weakness and wasting. [ncbi.nlm.nih.gov]

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Chronic Inflammatory Demyelinating Polyneuropathy

We described a young girl with CIDP underlying type 2 diabetes mellitus, presenting with progressive numbness and limb weakness, who was initially misdiagnosed to have DPN [ncbi.nlm.nih.gov]

Although at 25 years of age she had already been diagnosed with limb weakness associated with chronic inflammatory demyelinating polyneuropathy (CIDP), she had never experienced [ncbi.nlm.nih.gov]

Proximal limb weakness is a core feature of CIDP, differentiating this disorder from other neuropathies, which often involve more distal portion of limbs. [symptoma.com]

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Motor Neuron Disease

Selective distal upper limb muscle weakness and atrophy with non-significant lower limb weakness during follow-up was the most frequent motor pattern, present in 18 patients [ncbi.nlm.nih.gov]

Diagnostic pointers in limb-onset MND [ 1 ] Asymmetrical distal weakness frequently occurs. Brisk reflexes will occur in a wasted limb. [patient.info]

Limb weakness and dysphagia eventually become disabling, although some patients have a primarily bulbar pattern of weakness with relative sparing of limb strength. [emedicine.medscape.com]

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Limb-Girdle Muscular Dystrophy

Limb-girdle muscular dystrophies (LGMD) are a group of clinically and genetically heterogeneous diseases characterized by weakness and wasting of the pelvic and shoulder girdle [ncbi.nlm.nih.gov]

PATIENT CONCERNS: A 25-year-old woman was admitted to our department as the limb weakness progressively worsened. [ncbi.nlm.nih.gov]

A 40-year-old woman reported exercise-induced calf pain at age 34, followed by progressive lower and upper limb weakness. [ncbi.nlm.nih.gov]

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Acute Hepatic Porphyria

Severe, Diffuse Abdominal Pain1-5 1 Or More Of The Following PERIPHERAL Nervous System Limb weakness or pain CENTRAL Nervous System Anxiety Confusion AUTONOMIC Nervous System [porphyria.ca]

Signs and Symptoms of AHP 1 Central Nervous System Confusion Anxiety Seizures Insomnia Hallucinations Depression 2 Peripheral Nervous System Limb weakness or pain Numbness [porphyria.com]

Nausea and vomiting Muscular weakness Limb pain Quadriplegia Psychiatric symptoms like psychosis Anxiety Skin rash Blisters on sun-exposed areas Red-brown colored urine Diagnosis [lecturio.com]

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Myopathy

A 47-year-old man with liver cirrhosis developed limb weakness after liver transplantation. [ncbi.nlm.nih.gov]

Background Immune-mediated necrotising myopathies are characterised clinically by the subacute onset of proximal limb weakness, accompanied by elevated creatinine kinase levels [ncbi.nlm.nih.gov]

The dominant symptoms were exertion induced myalgia and progressive proximal limb weakness in all. 12/19 (63.2%) had classical dropped head syndrome. [ncbi.nlm.nih.gov]

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Multiple Sclerosis

Multiple sclerosis (MS) patients are referred to occupational therapy with complaints about fatigue, limb weakness, alteration of upper extremity fine motor coordination, [ncbi.nlm.nih.gov]

Cochrane Database of Systematic Reviews Background Multiple sclerosis (MS) patients are referred to occupational therapy with complaints about fatigue, limb weakness, alteration [doi.org]

She was currently in a remission phase from her MS but with persistent sequelae, including impaired eyesight and muscle weakness of the limbs. [ncbi.nlm.nih.gov]

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Leigh's Disease

There was no fever, seizures, limb weakness, or sensory symptoms. Personal and family history was unremarkable. General and other systemic examination was normal. [annalsofian.org]

Exercise intolerance, limb weakness, hearing loss, and diabetes may also precede the occurrence of the stroke-like episodes. [umdf.org]

Loss of sensation and weakness in the limbs (peripheral neuropathy), common in people with Leigh syndrome, may also make movement difficult. [mitoaction.org]

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Erb Muscular Dystrophy

Symptoms - Muscular dystrophy limb girdle type 2A- Erb type Muscle weakness is first evident in the shoulder girdle and later in the pelvic girdle. [checkorphan.org]

In 1954, when Walton and Nattrass reported 105 cases of limb-girdle weakness associated with many other disorders, the nosologic entity of limb-girdle dystrophy was formally [emedicine.medscape.com]

The weakness slowly gets worse, and people may need the aid of a cane or a walker. [icdlist.com]

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Brachial Plexus Neuropathy

Fourteen days post-transplant he developed rapidly progressive proximal weakness in both upper limbs. [nature.com]

The disease was characterized by repeated attacks of pain in the upper limb/shoulder region, followed by muscle weakness and atrophy. [ncbi.nlm.nih.gov]

Brachial plexus neuropathy is a disorder which usually occurs sporadically, and is characterized by pain and varying degrees of weakness in one or both upper limbs. [ncbi.nlm.nih.gov]

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Acute Intermittent Porphyria

[…] lower limbs. [ncbi.nlm.nih.gov]

In February 2012, he experienced recurrent urinary retention after onset of intestinal obstruction, irritability, hallucinations and delirium, lower limbs muscle pain, weakness [doi.org]

[…] or paralysis of the limbs, and psychic changes resembling hysteria. [britannica.com]

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Facioscapulohumeral Muscular Dystrophy

FSHD presentation with foot drop or lower limb proximal weakness appeared to be more frequent than expected. [ncbi.nlm.nih.gov]

[…] distal (22.45 %) or proximal lower limb weakness (14.8 %). 85.57 % patients were ambulant or ambulant with assistance at the time of registration, 7.9 % report respiratory [ncbi.nlm.nih.gov]

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Polymyositis

In her history, she had upper and lower limbs weakness accompanied by dysphagia which was further complicated by right bronchial aspiration 9 months ago. [ncbi.nlm.nih.gov]

Examination revealed multiple telangiactasia over face and nail beds and bilateral proximal lower limb weakness of power 4/5. [ncbi.nlm.nih.gov]

Muscle weakness is common and mainly involves the ‘proximal’ limb muscles (the muscles around the shoulders, upper arms, pelvis and thighs). [musculardystrophyuk.org]

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Spinal Cord Compression

We report a 7-year-3-month-old girl who suffered from neck pain with restricted movement, poor appetite, body weight loss, mild right limbs weakness, and a non-tender neck [ncbi.nlm.nih.gov]

We present the case of a 33-year-old Caucasian woman with a 10-day history of thoracic back pain and a 1-day history of sudden-onset bilateral lower limb weakness and paresthesia [ncbi.nlm.nih.gov]

We present a case of 50 year old male who came to the hospital with back pain and progressive bilateral lower limb weakness for the past 6 months. [ncbi.nlm.nih.gov]

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Bickerstaff Brainstem Encephalitis

One patient among Bickerstaff’s original cases had flaccid limb weakness, and BBE cases were divided into ‘BBE without limb weakness’ and ‘BBE with limb weakness’. [doi.org]

Table 6 Anti‐ganglioside IgG antibodies for patients with BBE and BBE with limb weakness IgG antibody to BBE, total BBE without limb weakness BBE with limb weakness ( n 62 [doi.org]

Table 3 Clinical profiles of patients with BBE and BBE with limb weakness Total BBE without limb weakness BBE with limb weakness Number of patients 62 25 37 Sex (male/female [doi.org]

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Lambert-Eaton Syndrome

Here, we describe a patient with a 5-year history of cervical myelopathy who presented with recurrent limb weakness of her limbs and complained of recent progressive weakness [ncbi.nlm.nih.gov]

Neurological examination revealed muscle weakness, predominantly in the proximal parts of the limbs. [ncbi.nlm.nih.gov]

A 27-year-old man as initially having the diagnosis of Addison's disease was admitted to the hospital because of fatigue, dry-mouthness and proximal limb weakness for 1 year [ncbi.nlm.nih.gov]

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Brachial Plexus Neuritis

Its classical presentation involves painful progressive asymmetrical upper limb weakness with sensory abnormalities. [jnnp.bmj.com]

After infections, surgery or stress Few episodes after 50 years Non-penetrance: Rare Pain Precedes weakness Increased by limb movement Weakness: Multifocal Course: Maximum [neuromuscular.wustl.edu]

[…] in upper limb muscles and hypertrophy of the brachial plexus brachial plexus hypertrophy can be seen on MRI typically painless INA begins with acute painful phase, followed [orthobullets.com]

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Glycogen Storage Disease Type 2

There may be limb-girdle weakness and weakness of respiratory muscles.[5] Signs Infantile form: Cardiomegaly and congestive heart failure. [patient.info]

The glycogen accumulation leads to myopathy / progressive muscle weakness, notably limb-girdle muscle weakness. [youtube.com]

Electromyography may be used initially to distinguish Pompe from other causes of limb weakness. [en.wikipedia.org]

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Adult Spinal Muscular Atrophy

As the disease progresses patients may notice limb weakness starting in the pelvis or shoulders, or weakness of the facial and tongue muscles. [cedars-sinai.edu]

weakness, hypotonia Bulbar palsy Late Microcephaly Oculomotor defects: strabismus, nystagmus, oculomotor apraxia Cognitive defects Life expectancy 1 year Diagnostics Genetic [amboss.com]

In addition to muscle weakness, clinical features include head lag, poor sucking and swallowing, weak cry, proximal limb weakness, and lack of reflexes. [encyclopedia.com]

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Diabetic Amyotrophy

BACKGROUND: People with diabetes mellitus (DM) sometimes present with acute or subacute, progressive, asymmetrical pain and weakness of the proximal lower limb muscles. [ncbi.nlm.nih.gov]

[…] involving predominantly the proximal muscles of the lower limbs; weakness that is not confined to one nerve or nerve root distribution; and exclusion of other causes of lumbosacral [ncbi.nlm.nih.gov]

[…] involving predominantly the proximal muscles of the lower limbs, weakness that is not confined to one nerve or nerve root distribution and exclusion of other causes of lumbosacral [ncbi.nlm.nih.gov]

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Myotonic Dystrophy

Patient-reported perceived changes (worse/stable) in balance, walking, lower-limb weakness, stair-climbing and hand weakness were used as criteria. [ncbi.nlm.nih.gov]

In the clinical neurological examination, there was a facial but no limb muscle weakness or atrophy. Ankle jerks were weak. [bmcresnotes.biomedcentral.com]

[…] muscle weakness as well as a bilateral winged scapula associated with atrophy of the pectoralis major muscle and lumbar lordosis; pelvic muscles were mostly spared. [ncbi.nlm.nih.gov]

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Spinal Muscular Atrophy

As the disease progresses patients may notice limb weakness starting in the pelvis or shoulders, or weakness of the facial and tongue muscles. [cedars-sinai.edu]

There is a clinical variant of SMA, known as autosomal-dominant spinal muscular atrophy characterized by a predominantly lower limb weakness and muscle wasting. [symptoma.com]

In addition to muscle weakness, clinical features include head lag, poor sucking and swallowing, weak cry, proximal limb weakness, and lack of reflexes. [encyclopedia.com]

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Nemaline Myopathy Type 4

neck, and limbs. [malacards.org]

LGMD2L (AR) P21 56 N/A Limb-girdle muscle weakness COL6A3 c.5658G A p.Arg1886Cys (VUS) - Bethlem myopathy (AD) P22 46 Limb-girdle muscle weakness DYSF c.2448 2 T G [ojrd.biomedcentral.com]

The muscle weakness, which begins at birth or during childhood, can worsen over time. [malacards.org]

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