Limb Weakness Causes & Reasons

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Limb Weakness Symptom Checker: Possible causes include Vitamin B12 Deficiency. Check the full list of possible causes and conditions now! Talk to our Chatbot to narrow down your search.

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Possible Causes

Vitamin B12 Deficiency

This can result in tingling in the feet and hands, weakness in the limbs, and even loss of sensation. [healthyandnaturalworld.com]

A 23-year-old man presented with weakness in the lower limbs, numbness in hands and feet over past 6 months. [ncbi.nlm.nih.gov]

He presented with weakness and numbness of the distal limbs and absent deep tendon reflex in all four extremities. [ncbi.nlm.nih.gov]

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Lumbar Disk Herniation

Weakness of affected limb due to possible nerve compression The above symptoms of Lumbar spondylosis which is predominantly due to vitiated Vata dosha. [bodhiwellnesscentre.com]

We report a 45-year-old male who presented with sudden onset right lower limb weakness after lifting heavy weight. [read.qxmd.com]

In some cases, it can lead to pain, numbness, or weakness in the limbs. However, some people experience no pain, particularly if the disk does not press on any nerves. [medicalnewstoday.com]

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Hypothyroidism

Here we describe a 3-year-old Caucasian girl who was admitted to our Clinic due to pericardial effusion, muscle weakness and weight gain. [ncbi.nlm.nih.gov]

At clinical examination, she presented with bradycardia, pale and round face, pseudohypertrophy of calf muscles and no pitting edema of the limbs. [ncbi.nlm.nih.gov]

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Polymyalgia Rheumatica

Weak or absent pulses may be noticed by the doctor. These symptoms occur in 15% to 20% of patients. What are the symptoms of PMR? [my.clevelandclinic.org]

Weak or absent pulses may be noticed by the doctor. These symptoms occur in 15 to 20% of patients. [my.clevelandclinic.org]

If narrowing occurs in the blood vessels leading to the arms or legs, patients may notice fatigue or aching in the limbs because of a reduced blood supply. [my.clevelandclinic.org]

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Primary Progressive Multiple Sclerosis

The exacerbations manifested as isolated optic neuritis in 9 patients, optic neuritis with limb paresis in 1, isolated diplopia in 2, diplopia with limb weakness in 1, limb [jamanetwork.com]

Symptoms can include: Pain (for example, headaches, pain in the legs and feet, back pain, and muscle spasms) Electric-shock sensations that run down the back and limbs when [hopkinsmedicine.org]

Pyramidal functional system impairment (ie, limb weakness, spasticity, or hyperreflexia) was seen in the following patterns, typically with sparing of the facial musculature [jamanetwork.com]

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Muscular Dystrophy

The symptoms of FSH dystrophy may appear during childhood with severe facial and limb weakness or develop slowly and gradually in adulthood with progressive difficulty closing [kennedykrieger.org]

Later on, after many years, mild limb weakness around the shoulders and hips may also develop. [patient.info]

[…] about Duchenne muscular dystrophy Facioscapulohumeral Muscular Dystrophy: Facioscapulohumeral (FSH) dystrophy is a common muscular dystrophy in which there is progressive weakness [kennedykrieger.org]

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Duchenne Muscular Dystrophy

And 2) are these gait deviations related to lower limb weakness? [ncbi.nlm.nih.gov]

Abstract Duchenne muscular dystrophy (DMD) is an X-linked form of muscular dystrophy characterized by progressive limb-girdle distribution of muscle weakness. [ncbi.nlm.nih.gov]

DMD typically appears between the ages of two with weakness in the pelvis and upper limbs, resulting in clumsiness, frequent falling, an unusual gait and general weakness. [medterms.com]

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Multifocal Motor Neuropathy

The initial high-dose intravenous immunoglobulin treatment significantly improved left upper limb muscle weakness. [ncbi.nlm.nih.gov]

Multifocal motor neuropathy is a disorder characterized by slowly progressive asymmetrical limb weakness and multiple motor conduction blocks. [ncbi.nlm.nih.gov]

Multifocal motor neuropathy (MMN) is typically associated with distal upper limb weakness and wasting. [ncbi.nlm.nih.gov]

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Chronic Inflammatory Demyelinating Polyneuropathy

We described a young girl with CIDP underlying type 2 diabetes mellitus, presenting with progressive numbness and limb weakness, who was initially misdiagnosed to have DPN [ncbi.nlm.nih.gov]

Although at 25 years of age she had already been diagnosed with limb weakness associated with chronic inflammatory demyelinating polyneuropathy (CIDP), she had never experienced [ncbi.nlm.nih.gov]

Proximal limb weakness is a core feature of CIDP, differentiating this disorder from other neuropathies, which often involve more distal portion of limbs. [symptoma.com]

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Motor Neuron Disease

Selective distal upper limb muscle weakness and atrophy with non-significant lower limb weakness during follow-up was the most frequent motor pattern, present in 18 patients [ncbi.nlm.nih.gov]

Diagnostic pointers in limb-onset MND [ 1 ] Asymmetrical distal weakness frequently occurs. Brisk reflexes will occur in a wasted limb. [patient.info]

Limb weakness and dysphagia eventually become disabling, although some patients have a primarily bulbar pattern of weakness with relative sparing of limb strength. [emedicine.medscape.com]

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Limb-Girdle Muscular Dystrophy

Limb-girdle muscular dystrophies (LGMD) are a group of clinically and genetically heterogeneous diseases characterized by weakness and wasting of the pelvic and shoulder girdle [ncbi.nlm.nih.gov]

PATIENT CONCERNS: A 25-year-old woman was admitted to our department as the limb weakness progressively worsened. [ncbi.nlm.nih.gov]

A 40-year-old woman reported exercise-induced calf pain at age 34, followed by progressive lower and upper limb weakness. [ncbi.nlm.nih.gov]

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Acute Hepatic Porphyria

Severe, Diffuse Abdominal Pain1-5 1 Or More Of The Following PERIPHERAL Nervous System Limb weakness or pain CENTRAL Nervous System Anxiety Confusion AUTONOMIC Nervous System [porphyria.ca]

Signs and Symptoms of AHP 1 Central Nervous System Confusion Anxiety Seizures Insomnia Hallucinations Depression 2 Peripheral Nervous System Limb weakness or pain Numbness [porphyria.com]

Nausea and vomiting Muscular weakness Limb pain Quadriplegia Psychiatric symptoms like psychosis Anxiety Skin rash Blisters on sun-exposed areas Red-brown colored urine Diagnosis [lecturio.com]

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Myopathy

A 47-year-old man with liver cirrhosis developed limb weakness after liver transplantation. [ncbi.nlm.nih.gov]

Background Immune-mediated necrotising myopathies are characterised clinically by the subacute onset of proximal limb weakness, accompanied by elevated creatinine kinase levels [ncbi.nlm.nih.gov]

The dominant symptoms were exertion induced myalgia and progressive proximal limb weakness in all. 12/19 (63.2%) had classical dropped head syndrome. [ncbi.nlm.nih.gov]

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Multiple Sclerosis

Multiple sclerosis (MS) patients are referred to occupational therapy with complaints about fatigue, limb weakness, alteration of upper extremity fine motor coordination, [ncbi.nlm.nih.gov]

Cochrane Database of Systematic Reviews Background Multiple sclerosis (MS) patients are referred to occupational therapy with complaints about fatigue, limb weakness, alteration [doi.org]

She was currently in a remission phase from her MS but with persistent sequelae, including impaired eyesight and muscle weakness of the limbs. [ncbi.nlm.nih.gov]

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Leigh's Disease

There was no fever, seizures, limb weakness, or sensory symptoms. Personal and family history was unremarkable. General and other systemic examination was normal. [annalsofian.org]

Exercise intolerance, limb weakness, hearing loss, and diabetes may also precede the occurrence of the stroke-like episodes. [umdf.org]

Loss of sensation and weakness in the limbs (peripheral neuropathy), common in people with Leigh syndrome, may also make movement difficult. [mitoaction.org]

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Erb Muscular Dystrophy

Symptoms - Muscular dystrophy limb girdle type 2A- Erb type Muscle weakness is first evident in the shoulder girdle and later in the pelvic girdle. [checkorphan.org]

In 1954, when Walton and Nattrass reported 105 cases of limb-girdle weakness associated with many other disorders, the nosologic entity of limb-girdle dystrophy was formally [emedicine.medscape.com]

The weakness slowly gets worse, and people may need the aid of a cane or a walker. [icdlist.com]

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Brachial Plexus Neuropathy

Fourteen days post-transplant he developed rapidly progressive proximal weakness in both upper limbs. [nature.com]

The disease was characterized by repeated attacks of pain in the upper limb/shoulder region, followed by muscle weakness and atrophy. [ncbi.nlm.nih.gov]

Brachial plexus neuropathy is a disorder which usually occurs sporadically, and is characterized by pain and varying degrees of weakness in one or both upper limbs. [ncbi.nlm.nih.gov]

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Acute Intermittent Porphyria

[…] lower limbs. [ncbi.nlm.nih.gov]

In February 2012, he experienced recurrent urinary retention after onset of intestinal obstruction, irritability, hallucinations and delirium, lower limbs muscle pain, weakness [doi.org]

[…] or paralysis of the limbs, and psychic changes resembling hysteria. [britannica.com]

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Facioscapulohumeral Muscular Dystrophy

FSHD presentation with foot drop or lower limb proximal weakness appeared to be more frequent than expected. [ncbi.nlm.nih.gov]

[…] distal (22.45 %) or proximal lower limb weakness (14.8 %). 85.57 % patients were ambulant or ambulant with assistance at the time of registration, 7.9 % report respiratory [ncbi.nlm.nih.gov]

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Polymyositis

In her history, she had upper and lower limbs weakness accompanied by dysphagia which was further complicated by right bronchial aspiration 9 months ago. [ncbi.nlm.nih.gov]

Examination revealed multiple telangiactasia over face and nail beds and bilateral proximal lower limb weakness of power 4/5. [ncbi.nlm.nih.gov]

Muscle weakness is common and mainly involves the ‘proximal’ limb muscles (the muscles around the shoulders, upper arms, pelvis and thighs). [musculardystrophyuk.org]

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Spinal Cord Compression

We report a 7-year-3-month-old girl who suffered from neck pain with restricted movement, poor appetite, body weight loss, mild right limbs weakness, and a non-tender neck [ncbi.nlm.nih.gov]

We present the case of a 33-year-old Caucasian woman with a 10-day history of thoracic back pain and a 1-day history of sudden-onset bilateral lower limb weakness and paresthesia [ncbi.nlm.nih.gov]

We present a case of 50 year old male who came to the hospital with back pain and progressive bilateral lower limb weakness for the past 6 months. [ncbi.nlm.nih.gov]

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Bickerstaff Brainstem Encephalitis

One patient among Bickerstaff’s original cases had flaccid limb weakness, and BBE cases were divided into ‘BBE without limb weakness’ and ‘BBE with limb weakness’. [doi.org]

Table 6 Anti‐ganglioside IgG antibodies for patients with BBE and BBE with limb weakness IgG antibody to BBE, total BBE without limb weakness BBE with limb weakness ( n 62 [doi.org]

Table 3 Clinical profiles of patients with BBE and BBE with limb weakness Total BBE without limb weakness BBE with limb weakness Number of patients 62 25 37 Sex (male/female [doi.org]

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Lambert Eaton Myasthenic Syndrome

Here, we describe a patient with a 5-year history of cervical myelopathy who presented with recurrent limb weakness of her limbs and complained of recent progressive weakness [ncbi.nlm.nih.gov]

Neurological examination revealed muscle weakness, predominantly in the proximal parts of the limbs. [ncbi.nlm.nih.gov]

A 27-year-old man as initially having the diagnosis of Addison's disease was admitted to the hospital because of fatigue, dry-mouthness and proximal limb weakness for 1 year [ncbi.nlm.nih.gov]

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Brachial Plexus Neuritis

Its classical presentation involves painful progressive asymmetrical upper limb weakness with sensory abnormalities. [jnnp.bmj.com]

After infections, surgery or stress Few episodes after 50 years Non-penetrance: Rare Pain Precedes weakness Increased by limb movement Weakness: Multifocal Course: Maximum [neuromuscular.wustl.edu]

[…] in upper limb muscles and hypertrophy of the brachial plexus brachial plexus hypertrophy can be seen on MRI typically painless INA begins with acute painful phase, followed [orthobullets.com]

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Glycogen Storage Disease Type 2

There may be limb-girdle weakness and weakness of respiratory muscles.[5] Signs Infantile form: Cardiomegaly and congestive heart failure. [patient.info]

The glycogen accumulation leads to myopathy / progressive muscle weakness, notably limb-girdle muscle weakness. [youtube.com]

Electromyography may be used initially to distinguish Pompe from other causes of limb weakness. [en.wikipedia.org]

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Adult Spinal Muscular Atrophy

As the disease progresses patients may notice limb weakness starting in the pelvis or shoulders, or weakness of the facial and tongue muscles. [cedars-sinai.edu]

weakness, hypotonia Bulbar palsy Late Microcephaly Oculomotor defects: strabismus, nystagmus, oculomotor apraxia Cognitive defects Life expectancy 1 year Diagnostics Genetic [amboss.com]

In addition to muscle weakness, clinical features include head lag, poor sucking and swallowing, weak cry, proximal limb weakness, and lack of reflexes. [encyclopedia.com]

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Diabetic Amyotrophy

BACKGROUND: People with diabetes mellitus (DM) sometimes present with acute or subacute, progressive, asymmetrical pain and weakness of the proximal lower limb muscles. [ncbi.nlm.nih.gov]

[…] involving predominantly the proximal muscles of the lower limbs; weakness that is not confined to one nerve or nerve root distribution; and exclusion of other causes of lumbosacral [ncbi.nlm.nih.gov]

[…] involving predominantly the proximal muscles of the lower limbs, weakness that is not confined to one nerve or nerve root distribution and exclusion of other causes of lumbosacral [ncbi.nlm.nih.gov]

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Myotonic Dystrophy

Patient-reported perceived changes (worse/stable) in balance, walking, lower-limb weakness, stair-climbing and hand weakness were used as criteria. [ncbi.nlm.nih.gov]

In the clinical neurological examination, there was a facial but no limb muscle weakness or atrophy. Ankle jerks were weak. [bmcresnotes.biomedcentral.com]

[…] muscle weakness as well as a bilateral winged scapula associated with atrophy of the pectoralis major muscle and lumbar lordosis; pelvic muscles were mostly spared. [ncbi.nlm.nih.gov]

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Spinal Muscular Atrophy

As the disease progresses patients may notice limb weakness starting in the pelvis or shoulders, or weakness of the facial and tongue muscles. [cedars-sinai.edu]

There is a clinical variant of SMA, known as autosomal-dominant spinal muscular atrophy characterized by a predominantly lower limb weakness and muscle wasting. [symptoma.com]

In addition to muscle weakness, clinical features include head lag, poor sucking and swallowing, weak cry, proximal limb weakness, and lack of reflexes. [encyclopedia.com]

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Nemaline Myopathy Type 4

neck, and limbs. [malacards.org]

LGMD2L (AR) P21 56 N/A Limb-girdle muscle weakness COL6A3 c.5658G A p.Arg1886Cys (VUS) - Bethlem myopathy (AD) P22 46 Limb-girdle muscle weakness DYSF c.2448 2 T G [ojrd.biomedcentral.com]

The muscle weakness, which begins at birth or during childhood, can worsen over time. [malacards.org]

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