Limb girdle muscular dystrophy (LGMD) is a group of genetic muscle disorders which are mainly characterized by weakness and wasting of the muscles of the pelvic and pectoral girdles. The disorders are caused by genetic mutations affecting proteins and pathways of muscle function. Generally, presentation varies…
Proximal limb weakness is a core feature of CIDP, differentiating this disorder from other neuropathies, which often involve more distal portion of limbs. … The disease presents with progressive development of proximal and distal limb weakness; muscles of hands and feet may be involved, affecting fine movements. … Classical CIDP In the classical form, CIDP presents with the following features: Symmetrical limb weakness, involving both proximal and distal extremities Sensory loss (usually … 
Multifocal motor neuropathy (MMN) is a rare disorder characterized by progressive, asymmetric limb weakness. … The resultant conduction block causes progressive limb weakness and differentiates this entity from clinically similar diseases. … According to these guidelines, there are two clinical core criteria: MMN patients present with a progressive, asymmetric limb weakness.
There is a clinical variant of SMA, known as autosomal-dominant spinal muscular atrophy characterized by a predominantly lower limb weakness and muscle wasting.
Upper and lower limb weakness, visual impairments and myotonia may lead to the need for mobility aids and functional adaptive equipment such as buttonhooks and handled sponges … 
Hemiplegic migraine is an unusual variant of migraine. Persons with this form of migraine have headaches associated with the loss of motor strength on one side of the body. A migraine is a recurrent throbbing headache. Typically, the pain only affects one side of the head. While classic migraine is often accompanied…
Adult spinal muscular atrophy is a genetic neurodegenerative disorder characterized by muscle wasting and weakness. In adults, normal life expectancy is achieved, as only mild weakness may be encountered. The diagnosis rests on confirming genetic mutations. Adult spinal muscular atrophy or spinal muscular atrophy…
Spinal muscular atrophies are a group of neurodegenerative disorders in which genetic mutations lead to progressive damage of motor neurons in the spinal cord. Type 1 is most severe, with a very early onset of numerous symptoms that lead to death within the first few years of life in the vast majority of cases.…
Diabetic amyotrophy is a complication of diabetes mellitus. Affected individuals suffer from painful, progressive damage to the lumbosacral plexus and consequent neurological deficits. Initially, DA manifests in form of severe, unilateral pain in buttocks, hips, and thighs. Similar symptoms subsequently affect the…