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227 Possible Causes for Limb Weakness, Muscle Twitch, Spasticity - Hyperreflexia

  • Multifocal Motor Neuropathy

    Upper motor neuron signs (spasticity, hyperreflexia, extensor plantar response).[clinicaltrials.gov] The initial high-dose intravenous immunoglobulin treatment significantly improved left upper limb muscle weakness.[ncbi.nlm.nih.gov] Usually beginning in one or both hands, MMN is characterized by weakness, muscle atrophy, cramping, and often profuse fasciculations (muscle twitching).[en.wikipedia.org]

  • Motor Neuron Disease

    Lower motor neuron (LMN) findings include muscle atrophy and fasciculations, and upper motor neuron (UMN) findings include hyperreflexia, spasticity, muscle spasm, and abnormal[en.wikipedia.org] A 69-year-old man with long-standing depression and failing memory presented with muscle twitches of 8 months' duration.[ncbi.nlm.nih.gov] Selective distal upper limb muscle weakness and atrophy with non-significant lower limb weakness during follow-up was the most frequent motor pattern, present in 18 patients[ncbi.nlm.nih.gov]

  • Amyotrophic Lateral Sclerosis Type 4

    hyperreflexia ( ) Hoffman's ( ) Babinski's spastic dysarthria lower motor neuron (LMN) signs muscular atrophy weakness clinical fasciculations clumsiness Evaluation Diagnosis[orthobullets.com] They may seek medical advice due to progressive distal limb weakness and subsequent muscle wasting.[symptoma.com] . [1] [2] There are various types of ALS that are distinguished by symptoms and, in some cases, genetic cause. [2] Early symptoms may include muscle twitching, cramping, stiffness[rarediseases.info.nih.gov]

  • Amyotrophic Lateral Sclerosis Type 9

    Additional symptoms typical of ALS, such as fasciculations, spasticity, and hyperreflexia, have also been described in ALS9 patients.[symptoma.com] Unable to function, the muscles gradually weaken, start to twitch (called fasciculations), and waste away (atrophy).[ninds.nih.gov] Bulbar onset is common but ALS9 patients also suffer from limb muscle weakness and show pyramidal signs.[symptoma.com]

  • Primary Progressive Multiple Sclerosis

    Affected individuals may have tremors, muscle stiffness (spasticity), exaggerated reflexes (hyperreflexia), weakness or partial paralysis of the muscles of the limbs, difficulty[icdlist.com] Symptoms can include: Pain (for example, headaches, pain in the legs and feet, back pain, and muscle spasms) Electric-shock sensations that run down the back and limbs when[hopkinsmedicine.org] Typical symptoms associated with PML are diverse, progress over days to weeks, and include progressive weakness on one side of the body or clumsiness of limbs, disturbance[ocrevus.com]

  • Upper Motor Neuron Disease

    No spasticity or hyperreflexia.[brainscape.com] weakness Advanced stage: Weakness in the muscles, in particular the limbs, where movement becomes more and more difficult The limb muscles begin to shrink and some develop[newhealthadvisor.com] Lower motor neuron disease causes weakness, loss of muscle ("atrophy") and muscle twitching ("fasciculations").[neurology.emory.edu]

  • Peripheral Motor Neuropathy

    However, hyperreflexia and spasticity typical of ALS never occur in MMN. Conduction block Amount of block increases with more proximal stimulation. B.[neuromuscular.wustl.edu] Motor neuropathy symptoms may include: Muscle weakness Cramps Muscle twitching Loss of muscle and bone Changes in skin, hair, or nails Sensory neuropathy symptoms may include[stlouischildrens.org] weakness in individual motor nerve distribution with or without persistent conduction block preferentially affecting young man.[neurology.org]

  • Amyotrophic Lateral Sclerosis Type 1

    hyperreflexia ( ) Hoffman's ( ) Babinski's spastic dysarthria lower motor neuron (LMN) signs muscular atrophy weakness clinical fasciculations clumsiness Evaluation Diagnosis[orthobullets.com] Diagnostic pointers in limb-onset MND [ 1 ] Asymmetrical distal weakness frequently occurs. Brisk reflexes will occur in a wasted limb.[patient.info] Muscles twitch (called fasciculations) and waste away.[msdmanuals.com]

  • Progressive Muscular Atrophy

    Clinical Loss of fine motor skills, triad of atrophic weakness of hands and forearms; leg spasticity; generalised hyperreflexia. Management Possibly riluzole.[medical-dictionary.thefreedictionary.com] This then leads to fasciculations (muscle twitches), progressively worsening muscle weakness, and a loss of muscle mass and weight.[mndcentre.org.uk] However, hyperreflexia and spasticity typical of ALS never occur in MMN. Conduction block Amount of block increases with more proximal stimulation. B.[neuromuscular.wustl.edu]

  • Hallervorden-Spatz Syndrome

    Described features include 9,11 : progressive dementia extrapyramidal signs (rigidity, dystonia, choreoathetosis) corticospinal signs (spasticity, hyperreflexia) dysarthria[radiopaedia.org] They may experience involuntary muscle contractions (dystonia) of the head and neck, resulting in repetitive movements and contortions.[ghr.nlm.nih.gov] […] tremor writhing movements dementia spasticity weakness seizures (rare) toe walking retinitis pigmentosa, another degenerative disease that affects the individual’s retina[en.wikipedia.org]

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