80 Possible Causes for Lip Blisters in USA

  • Insect Bite
    Lip Swelling

    Insect bites may be inflicted by mosquitos, fleas, bugs, lice and a plethora of other species pertaining to distinct families of the order insects. While they are of little medical interest in the vast majority of cases, immunocompromised or allergic patients may suffer from severe reactions to an insect bite. Most…[1]

  • Stevens-Johnson Syndrome
    Cracked Lips Lip Blisters

    Ulcers and other lesions begin to appear in the mucous membranes, almost always in the mouth and lips, but also in the genital and anal regions. … The skin pattern most commonly associated with SJS is widespread, often joined or touching (confluent), papuric spots (macules) or flat small blisters or large blisters which … A few days later the skin begins to blister and peel forming painful raw areas.[2] [3]

  • Methotrexate
    Lip Blisters

    Methotrexate (MTX), formerly known as amethopterin, is a chemotherapy agent and immune system suppressant. It is used to treat cancer, autoimmune diseases, ectopic pregnancy, and for medical abortions. Types of cancers it is used for include breast cancer, leukemia, lung cancer, lymphoma, and osteosarcoma. Types…[4]

  • Brandt Syndrome
    Lip Blisters

    Brandt syndrome (BS) is also called acrodermatitis enteropathica (AE). It is a congenital disease that causes zinc deficiency due to malabsorption. Inherited in an autosomal recessive pattern, BS characteristically presents with dermatitis, diarrhea and hair loss. Brandt syndrome (BS) is an autosomal recessive inborn…[5]

  • Herpes Labialis
    Lip Blisters

    In time, these fluid-filled blisters form a cluster on the lip (labial) tissue, the area between the lip and skin (vermilion border), and can occur on the nose, chin, and … Otherwise, young children may present with febrile herpetic stomatitis, with small blisters and 2 to 10 mm ulcers in the mouth, tongue, and lips. … When reactivation occurs, the virus travels down the nerves to the skin where it may cause blisters (cold sores) around the lips, in the mouth or, in about 10% of cases, on … [6] [7]

  • Plasma Cell Gingivitis
    Lip Blisters

    If cheilitis is present, then the lip(s) will be dry, swollen, and fissured. … Another critical component of the evaluation is a thorough oral exam of the gums, teeth, mouth, tongue and lips. … Although rare, PCG may be accompanied by cheilitis, which is characterized by lip swelling, dryness, atrophy, and the formation of fissures.[8]

  • Bullous Pemphigoid

    The blistering disease usually occurs along the lines of the creases and skin folds but may rarely occur on the lips and eye mucosa. … The skin surrounding the blisters may appear normal or reddened. … These blisters occurs in the area of the lower abdomen, upper thighs and armpits.[9] [10]

  • Pemphigus Foliaceus

    The blisters rupture easily because the superficial skin overlying the blisters is quite thin. … These blisters are often very fragile. … Fluid fills these gaps and forms superficial blisters.[11] [12]

  • Erythema Multiforme

    papules distributed acrally with involvement of one or more mucous membranes; epidermal detachment involves less than 10% of total body surface area (TBSA) SJS/TEN—widespread blisters[13]

  • Chemical Burn

    Chemical warfare products such as sulfur and nitrogen mustards are blistering agents. … The clinical picture may feature any of the following signs at the site of contact: redness, irritation, burning, pain, numbness, blister formation, or darkened skin. … Bleach Ammonia Silver nitrate Hydrochloric acid Sulfuric acid Phosphoric acid Acetic acid Calcium hydroxide Sulfur mustard Vesicants Skin burns exhibit the following: Rash Blistering[14]

Further symptoms

Similar symptoms


  1. Insect Bite, Symptoma
  2. Stevens-Johnson Syndrome, Symptoma
  3. Stevens–Johnson syndrome, Wikipedia, CC-BY-SA-3.0
  4. Methotrexate, Wikipedia, CC-BY-SA-3.0
  5. Brandt Syndrome, Symptoma
  6. Herpes Labialis, Symptoma
  7. Herpes labialis, Wikipedia, CC-BY-SA-3.0
  8. Plasma Cell Gingivitis, Symptoma
  9. Bullous Pemphigoid, Symptoma
  10. Bullous pemphigoid, Wikipedia, CC-BY-SA-3.0
  11. Pemphigus Foliaceus, Symptoma
  12. Pemphigus foliaceus, Wikipedia, CC-BY-SA-3.0
  13. Erythema multiforme, Wikipedia, CC-BY-SA-3.0
  14. Chemical Burn, Symptoma