152 Possible Causes for Lithium Toxicity in USA

  • Lithium Toxicity

    Lithium toxicity can be acute or chronic in nature. … Definition: Lithium toxicity is defined as ingestion of over 1.2mEq/L of lithium. … Elderly patients with lithium toxicity has a worse prognosis.[1]

  • Diabetes Insipidus

    It is seen in lithium toxicity, hypercalcemia, hypokalemia, or release of ureteral obstruction. … Clinicians have been aware of lithium toxicity for many years, and traditionally have administered thiazide diuretics for lithium-induced polyuria and nephrogenic diabetes … Lithium-induced nephrogenic DI may be effectively managed with the administration of amiloride, a potassium-sparing diuretic often used in conjunction with thiazide or loop … [2] [3]

  • Nephrogenic Diabetes Insipidus

    Lithium in the cells primarily targets and inhibits glycogen synthase kinase 3, so this inhibition mediates the toxic effects of lithium use. … Adult-onset disease is almost always acquired and most commonly results from hypercalcemia and lithium toxicity. … The major causes of acquired NDI that produce clinical symptoms (e.g. polyuria) in the adult are lithium toxicity and high blood calcium.[4] [5]

  • Indomethacin
    Toxic Nephropathy

    Thus indometacin users have an elevated risk of lithium toxicity. … For patients taking lithium (e.g. for treatment of depression or bipolar disorder), less toxic NSAIDs such as sulindac or aspirin are preferred. … Indometacin has a high acute toxicity both for animals (in rats, 12 mg/kg) and for humans.[6]

  • Lithium
    Lithium Toxicity

    Dilithium List of countries by lithium production Lithium as an investment Lithium compounds Lithium (medication) Lithium soap Lithium-ion battery Lithium–air battery Lithium … aluminium production, lithium batteries, and lithium-ion batteries. … In moist air, lithium rapidly tarnishes to form a black coating of lithium hydroxide (LiOH and LiOH·H2O), lithium nitride (Li3N) and lithium carbonate (Li2CO3, the result … [7]

  • Angiotensin-Converting Enzyme Inhibitor
    Lithium Toxicity Toxic Nephropathy
  • Fosinopril
    Lithium Toxicity

    Fosinopril is an angiotensin converting enzyme (ACE) inhibitor used for the treatment of hypertension and some types of chronic heart failure. Fosinopril is the only phosphinate-containing ACE inhibitor marketed, by Bristol-Myers Squibb under the trade name Monopril. Fosinoprilat proved to have the same problem as…[8]

  • Diclofenac
    Lithium Toxicity Toxic Nephropathy

    However, diclofenac appears to have a different mechanism of renal toxicity. … The drug's use in animals is controversial due to its toxicity which can rapidly kill scavenging birds that eat dead animals. … The mechanism is presumed to be renal failure, however toxicity may be due to direct inhibition of uric acid secretion in vultures.[9]

  • Thiazide Diuretic
    Lithium Toxicity Toxic Erythema Toxic Nephropathy
  • Electrolytes Abnormal

Further symptoms

Similar symptoms


  1. Lithium Toxicity, Symptoma
  2. Diabetes Insipidus, Symptoma
  3. Diabetes insipidus, Wikipedia, CC-BY-SA-3.0
  4. Nephrogenic Diabetes Insipidus, Symptoma
  5. Nephrogenic diabetes insipidus, Wikipedia, CC-BY-SA-3.0
  6. Indometacin, Wikipedia, CC-BY-SA-3.0
  7. Lithium, Wikipedia, CC-BY-SA-3.0
  8. Fosinopril, Wikipedia, CC-BY-SA-3.0
  9. Diclofenac, Wikipedia, CC-BY-SA-3.0