Liver Biopsy: Causes & Reasons

Possible Causes for Liver Biopsy

Who should undergo liver biopsy? Not all patients with hemochromatosis need to undergo liver biopsy. [medicinenet.com]

For the liver biopsy, a thin needle is inserted into the liver while the patient is under local anesthesia. [medical-dictionary.thefreedictionary.com]

[…] severe iron overload in parenchymal cells, Kupffer cells, and periportal fibrosis on liver biopsy. [ncbi.nlm.nih.gov]

Portal Cirrhosis

Early cirrhosis is often diagnosed by liver stiffness measurement (Fibroscan®). Sometimes a liver biopsy is required to confirm the diagnosis of early cirrhosis. [singhealth.com.sg]

Sensitivity of liver biopsy approaches 100%. Nonalcoholic fatty liver disease (NAFLD) may be evident on ultrasound scans. [merckmanuals.com]

A high index of suspicion and a liver biopsy are needed to make the diagnosis in these patients. 4. [link.springer.com]

Alcoholic Liver Disease

Abstract Liver biopsy due to the limitations is not recommended for all patients with suspected Alcoholic Liver Disease (ALD) but useful for establishing the stage and severity [ncbi.nlm.nih.gov]

Liver biopsy 3 months after liver transplantation showed acute rejection and mild steatohepatitis. [ncbi.nlm.nih.gov]

biopsy. [ncbi.nlm.nih.gov]

Macronodular Cirrhosis

Histology: Liver biopsy (punction): no cirrhosis, increased amount of hemosiderin on the periphery of liver lobules. [atlases.muni.cz]

biopsy Cholestasis Primary biliary cirrhosis AMA, IgM, liver biopsy Secondary biliary cirrhosis MRCP, ERCP, liver biopsy Primary sclerosing cholangitis MRCP, ERCP, liver [abdominalkey.com]

[…] evaluation at our center underwent a liver biopsy examination. [ncbi.nlm.nih.gov]

Viral Hepatitis

Methods: A total of 302 patients with chronic hepatitis B or C, who had undergone liver biopsy, were retrospectively enrolled. [ncbi.nlm.nih.gov]

Before RTE, all patients underwent a US-guided percutaneous liver biopsy (right lobe). [ncbi.nlm.nih.gov]

This report describes unusual foci of hepatocellular hemosiderosis ("iron-rich foci" or IRF) in liver biopsy specimens from three patients with chronic hepatitis with or without [ncbi.nlm.nih.gov]

Hepatocellular Carcinoma

(D) Liver biopsy (HE). Histologic sections show loss of tissue architecture, with hepatocytes arranged in trabeculae or acini. (E) Liver biopsy (cytokeratin AE1/AE3). [ascopubs.org]

Liver Biopsy A liver biopsy offers a definitive diagnosis but may not be necessary. [hopkinsmedicine.org]

The risk of bleeding or other injury during a liver biopsy is usually low. [merckmanuals.com]

Chronic Hepatitis C

Are There Alternatives to Liver Biopsy? [healio.com]

MATERIALS AND METHODS: Patients were prospectively enrolled for paired liver biopsy and transient elastography. [ncbi.nlm.nih.gov]

[…] fibrosis in HCV-related chronic liver disease patients with good diagnostic performance comparable to that of liver biopsy and TE. [ncbi.nlm.nih.gov]

Acute Liver Failure

Liver biopsy revealed massive infiltration of neutrophils, but the cause of the acute hepatitis was not identified. [ncbi.nlm.nih.gov]

Diagnosis is based on findings of a paucity of bile ducts on liver biopsy combined with ≥3 of 5 major clinical criteria. [ncbi.nlm.nih.gov]

The patients had liver biopsies showing diffuse lobular necroinflammation, of which two had evidence of hemophagocytosis on histopathology. [ncbi.nlm.nih.gov]

Acute Fatty Liver of Pregnancy

iron studies, HFE genotype, and liver biopsy. [doi.org]

Liver biopsy interpretation continues to play an integral role in diagnosis and management of most forms of liver disease. [ncbi.nlm.nih.gov]

Liver biopsy was done on the 5th to 15th postpartum day in 8 cases. [ncbi.nlm.nih.gov]

Focal Nodular Hyperplasia

The role of liver biopsy in children for the diagnosis of FNH is unclear. [ncbi.nlm.nih.gov]

The transjugular approach was used to perform a random liver biopsy to assess the amount of hepatic necrosis and to perform the focal lesion biopsy orienting the needle with [ncbi.nlm.nih.gov]

KEYWORDS: Differential diagnosis; Focal nodular hyperplasia; Hepatocellular adenoma; Hepatocellular carcinoma; Liver biopsy [ncbi.nlm.nih.gov]

Autoimmune Hepatitis

A 61-year-old male was referred to our hospital because of abnormal liver enzyme levels after initial diagnosis of CAEBV had been made by laboratory tests and liver biopsy [ncbi.nlm.nih.gov]

Liver biopsy showed prominent interface hepatitis with MS. A drug-lymphocyte stimulation test (DLST) using EE2 was positive. [ncbi.nlm.nih.gov]

biopsy, and none of the patients consented for transjugular liver biopsy. [tropicalgastro.com]

Primary Biliary Cirrhosis

[…] or liver biopsy. [ucsfhealth.org]

A liver biopsy uses a thin needle to remove a small sample of liver tissue. The sample is then examined with a microscope. [oregonclinic.com]

During a liver biopsy, a small sample of tissue is removed from your liver using a thin needle. [ucsfhealth.org]

Hepatic Sarcoidosis

The diagnosis is based on a characteristic histopathological finding of liver biopsy. [ncbi.nlm.nih.gov]

Liver biopsy revealed non-caseating granuloma in 88% (14 of 16 patients). A total of four patients developed cirrhosis. [ncbi.nlm.nih.gov]

Liver biopsy showed non caseating granulomas. [ncbi.nlm.nih.gov]

Chronic Active Hepatitis B

As noted in Question 3, when the role of liver biopsy was discussed, in patients with chronic hepatitis C virus (HCV), a liver biopsy is also only necessary in patients with [healio.com]

The intrahepatic distribution of HBcAg was studied in liver biopsies of 14 patients with chronic active hepatitis B (CAH-B) (5 were hepatitis B e antigen [HBeAg]+/anti-HBe [ncbi.nlm.nih.gov]

We studied biopsy or autopsy tissue samples from 57 patients with chronic active hepatitis B for morphologic differences between chronic delta-positive and delta-negative [ncbi.nlm.nih.gov]

Hereditary Fructose Intolerance

A second liver biopsy 10 months later had normal aldolase B activity towards fructose-1-phosphate and a fructose tolerance test was also normal. [ncbi.nlm.nih.gov]

The usefulness of 2 diagnostic procedures, fructose tolerance test (FTT) and aldolase assay on biopsied liver, was studied. [ncbi.nlm.nih.gov]

Traditionally, diagnosis has been made by intravenous fructose challenge or by liver biopsy, both difficult and risky invasive tests. [ncbi.nlm.nih.gov]

Liver Transplant Rejection

Surgical liver biopsies (either open liver biopsy or laparoscopic liver biopsy) are typically performed when patients require a surgical procedure for another indication. [intechopen.com]

Key words Liver transplantation Liver, radionuclide studies Liver biopsy This is a preview of subscription content, log in to check access. [link.springer.com]

[…] patients with biopsy evidence for rejection, cholestasis or neither condition, we reviewed scintigrams and biopsies in 36 patients. [ncbi.nlm.nih.gov]

Alcoholic Fatty Liver

Patients with paired liver biopsies and LSM were followed prospectively for liver-related and non-liver related complications, and survival. [ncbi.nlm.nih.gov]

A liver biopsy was performed on all the patients. Results Of 96 patients undergoing liver biopsy for non-alcoholic fatty liver disease (NAFLD), 76 (79.2%) were men. [ncbi.nlm.nih.gov]

Clinicopathological features at the time of liver biopsy and factors related to hepatocellular carcinoma (HCC) occurrence were compared between the groups. [ncbi.nlm.nih.gov]

Cholesterol Ester Storage Disease

The biopsy appearances were compared with those of biopsies of other causes of fatty liver. [ncbi.nlm.nih.gov]

Laboratory tests showed elevated liver serum enzymes and dyslipidemia. Liver biopsy was consistent with CESD. [scielo.br]

Liver biopsy showed fat storage in hepatocytes. [genecelltissue.com]

Cardiac Cirrhosis

liver biopsy. [healthfrom.com]

Advanced fibrosis (stage F3-F4) on liver biopsy independently predicts all-cause and liver-related mortality in NASH. [pubfacts.com]

Liver biopsy in 2000 showed normal architecture. [gastrohep.com]

Wilson Disease

If any results are abnormal, liver biopsy is done to measure hepatic copper concentration. [msdmanuals.com]

Anti-smooth muscle antibody was positive 1:20, and liver biopsy showed micronodular cirrhosis with abundant Mallory hyaline and stainable copper deposits. [ncbi.nlm.nih.gov]

Diagnosis is based on a low serum ceruloplasmin level, high urinary excretion of copper, and sometimes liver biopsy results. [msdmanuals.com]

Hepatocellular Adenoma

KEYWORDS: Differential diagnosis; Focal nodular hyperplasia; Hepatocellular adenoma; Hepatocellular carcinoma; Liver biopsy [ncbi.nlm.nih.gov]

Liver biopsy revealed diffuse expression of β-catenin and a partial hepatic resection was performed. [ncbi.nlm.nih.gov]

METHODS: We included all patients with a hospital discharge diagnosis for benign liver tumour (ICD-10: D13.4) in 1997-2012 and a liver biopsy confirming the hepatocellular [ncbi.nlm.nih.gov]

Alpha-1 Antitrypsin Deficiency

A liver biopsy revealed cirrhosis with a dense mononuclear cell infiltrate. [ncbi.nlm.nih.gov]

METHODS: Study includes 33 participants, 11 per group, who underwent clinical research evaluation, liver biopsy (AAT and NAFLD groups), and MRE. [ncbi.nlm.nih.gov]

Liver biopsy is not required for diagnosis but can help to support it. [unboundmedicine.com]

Angiosarcoma of the Liver

Due to the vascularity of angiosarcoma, liver biopsy may be hazardous and can be avoided when there is a history of exposure to vinyl chloride monomer and the CT findings [ncbi.nlm.nih.gov]

Conclusions Liver biopsies are difficult to obtain from patients with cryptogenic liver failure. [surgicalcasereports.springeropen.com]

To confirm the diagnosis, a liver biopsy needs to be done, frequently giving rise to many bleeding and fibrosis related complications thereafter. [symptoma.com]

Reye Syndrome

The muscle biopsy results were compared with those of liver biopsies in 7 patients including one patient with definite RS and 6 with mimicking RS. [ncbi.nlm.nih.gov]

The liver biopsy of each patient revealed changes in centrilobular hepatocytes rather than the diffuse small droplet fatty change characteristic of Reye syndrome. [ncbi.nlm.nih.gov]

The diagnosis of Reye syndrome was confirmed by a liver biopsy and at autopsy. [ncbi.nlm.nih.gov]

Granulomatous Liver Disease

Abstract Hepatic granulomas are often encountered on liver biopsy and may represent a primary hepatic process, a manifestation of a systemic illness, or an innocent finding [ncbi.nlm.nih.gov]

Liver biopsy was performed (Figure 1). [gastrohep.com]

A 56-year-old man with persistently elevated liver enzyme levels, fatigue, lethargy and a 9.0 kg weight loss over six months underwent a percutaneous liver biopsy that demonstrated [ncbi.nlm.nih.gov]

Peliosis Hepatis

A Fatal Case of Intra-Abdominal Hemorrhage Following Diagnostic Blind Percutaneous Liver Biopsy in a Patient With Peliosis Hepatis Abstract Peliosis hepatis (PH) is a rare [gastrores.org]

The liver biopsy under laparoscopy revealed marked sinusoidal dilatation and retention of red blood cells, which was consistent with a diagnosis of peliosis hepatis. [ncbi.nlm.nih.gov]

Liver biopsy is necessary to establish diagnosis. By withdrawing the offending drug or treatment of the underlying disorder, regression may be observed. [ncbi.nlm.nih.gov]

Syphilitic Liver Cirrhosis

Coverage also includes a timely discussion on liver transplantation...and speculations on the future of the liver biopsy. [books.google.de]

Changes consistent with liver cirrhosis and splenomegaly were identified on computed tomography; liver biopsy showed chronic portal tract inflammation. [medicalxpress.com]

The architecture of the entire liver and its vasculature is disrupted. This fragment of cirrhotic liver was sampled by liver biopsy. [pathologylearningcentre.uct.ac.za]

Gaucher Disease

Based on bone marrow (BM) findings and on liver biopsy showing extramedullary hematopoiesis, an initial diagnosis of PMF was formulated. [ncbi.nlm.nih.gov]

Perform chest radiography to evaluate pulmonary manifestations.  Bone marrow examination for the presence of Gaucher’s cells is diagnostic.  Liver biopsy – Liver biopsy [slideshare.net]

A bone marrow or liver biopsy is not necessary to establish the diagnosis. [genome.gov]

Gaucher Disease Type 1

A liver biopsy specimen demonstrated Gaucher cells in Glisson's capsule. [karger.com]

Case 1 evaluated the misdiagnosis (from childhood) of spherocytosis in a 37-year-old Caucasian woman, which resulted in an inappropriate liver biopsy and delayed appropriate [mdmag.com]

Liver disease (but not Gaucher disease [GD]) was suspected and therefore a liver biopsy was performed. [touchoncology.com]

Liver Cirrhosis

liver biopsy. [web.archive.org]

biopsy 3.1 PERCUTANEOUS LIVER BIOPSY Percutaneous liver biopsy may be classified according to the site of entry of the biopsy needle, whether the biopsy is performed in a [web.archive.org]

The use and evidence for image guided liver biopsy is controversial and will be discussed. 3.1.3 Plugged liver biopsy Plugged liver biopsy is a modification of the percutaneous [web.archive.org]