Possible Causes for Liver Biopsy Abnormal in USA

  • Gaucher Disease
    Liver Biopsy Abnormal

    Gaucher disease is a lysosomal storage disease in which enzyme deficiency leads to accumulation of glycolipids in various tissues, mainly in the monocyte-macrophage system. It is transferred by autosomal recessive pattern of inheritance and depending on the subtype, patients may present with hepatosplenomegaly,…[1]

  • Familial Generalized Lipodystrophy
    Liver Biopsy Abnormal
  • Glycogen Storage Disease Type 4
    Liver Biopsy Abnormal

    Glycogen storage disease type IV, also known as Glycogen branching enzyme deficiency, Andersen's disease or amylopectinosis is a rare inherited metabolic disorder. Clinically there are many variations in presentation. As soon as the disease begins, there is accumulation of the long un-branched chains mainly in the…[2]

  • Phosphorylase Kinase Deficiency
    Liver Biopsy Abnormal
  • Hepatic Veno-Occlusive Disease
    Liver Biopsy Abnormal

    Hepatic veno-occlusive disease is a life-threatening condition in which toxic substances (either chemotherapeutic drugs or pyrrolizidine alkaloids found in various herbal remedies) cause severe damage to the endothelial cells of sinusoidal vessels in the liver, resulting in massive fibrosis and blood flow obstruction.…[3]

  • Autoimmune Hepatitis
    Liver Biopsy Abnormal Liver Biopsy

    Oettinger et al. published a series of 142 children with autoimmune hepatitis. Findings included: Jaundice 58% Non specific weakness 57% Anorexia 47% Abdominal pain 38%  Paleness 26% Other symptoms and signs may include: General discomfort or uneasiness  Abdominal distension Pruritis Diarrhea Edema Weight loss Spider…[4]

  • Primary Biliary Cirrhosis
    Liver Biopsy Abnormal Liver Biopsy showing Abnormal Bile Duct Proliferation Liver Biopsy

    Primary biliary cirrhosis (PBC) is a chronic and progressive disease of the liver which involves destruction of the interlobular bile ducts. In many cases, primary biliary cirrhosis causes no symptoms. However, in certain percentage of individuals this disease is known to cause the following signs and symptoms: Dry…[5]

  • Chronic Hepatitis C
    Liver Biopsy Abnormal Liver Biopsy

    Hepatitis C is an infectious disease caused by the hepatitis C virus. If such an infection persists for more than six months, it is deemed chronic hepatitis C, and this condition bears high risks of liver cirrhosis or malignant degeneration. An acute stage of hepatitis C infection has been described, but most patients…[6]

  • Hepatitis B
    Liver Biopsy Abnormal

    Hepatitis B is a form of viral hepatitis, caused by the hepatitis B virus, a member of the Hepadnavirus family. It is estimated that worldwide, more than 350 million people have chronic hepatitis B virus infection. The course of the disease may be extremely variable, depending on the patient’s age and immune status.…[7]

  • Hepatocellular Adenoma
    Liver Biopsy Abnormal Liver Biopsy

    Hepatocellular adenomas are benign tumors of liver closely linked to oral contraceptive and anabolic steroid use that usually involve the right hepatic lobe. Cases have also been described in type I and III glycogen storage diseases and men with metabolic syndrome. Often clinically silent, this condition may be found…[8]

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References

  1. Gaucher Disease, Symptoma
  2. Glycogen Storage Disease Type 4, Symptoma
  3. Hepatic Veno-Occlusive Disease, Symptoma
  4. Autoimmune Hepatitis, Symptoma
  5. Primary Biliary Cirrhosis, Symptoma
  6. Chronic Hepatitis C, Symptoma
  7. Hepatitis B, Symptoma
  8. Hepatocellular Adenoma, Symptoma
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