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Autoimmune Hepatitis
Liver Biopsy Abnormal
Liver Biopsy
Biopsy will show Ag-Ab aggregates in the liver. … However, the diagnosis of autoimmune hepatitis always requires a liver biopsy. … Laboratory Tests Complete blood count Liver function tests Serology for ANAs, SMAs, LKM1, anti-LC1 Immunoglobulins and albumen levels Blood profile Imaging Studies Liver biopsy … [1]
[2]
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Primary Biliary Cirrhosis
Liver Biopsy Abnormal
Liver Biopsy
However, a liver biopsy is needed to determine the stage of disease. … In many instances, biopsy of the liver tissue is also done to confirm diagnosis. … Imaging studies such as MRI and CT scan of the liver would have to be carried out to look for abnormalities in the organ.[3]
[4]
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Chronic Hepatitis C
Liver Biopsy Abnormal
Liver Biopsy
In some cases, a liver biopsy needs to be obtained. … on biopsy. … Liver biopsies are used to determine the degree of liver damage present; however, there are risks from the procedure.[5]
[6]
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Hepatitis B
Liver Biopsy Abnormal
Histologic testing is done by performing a liver biopsy especially for chronic hepatitis cases in which the findings show ground glass appearance of hepatocytes due to infiltration … Individuals with high viral loads, characteristically have ground glass hepatocytes on biopsy. … Co-infection with hepatitis D increases the risk of liver cirrhosis and liver cancer.[7]
[8]
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Hepatic Veno-Occlusive Disease
Liver Biopsy Abnormal
A liver biopsy is required for a definitive diagnosis. … Finally, liver biopsy and evaluation of hepatic vein pressure through the transjugular route may be performed and are effective, but highly risky procedures that may confirm … A biopsy may be performed in cases when the diagnosis is inconclusive, but the procedure carries a great risk.[9]
[10]
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Generalized Lipodystrophy
Liver Biopsy Abnormal
It may result in abnormal proliferation of mitochondria, known as mitochondrial toxicity. … Fasting blood glucose, lipid profile, liver enzymes, uric acid, creatinine and urinalysis should be obtained. … Hypertriglyceridemia, liver cirrhosis, diabetes mellitus, as well as cardiovascular complications are frequently observed.[11]
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Glycogen Storage Disease Type 4
Liver Biopsy Abnormal
Coagulation studies will be abnormal due to altered liver function. … It commonly affects the liver and abnormal liver function is seen in infants and children especially. … Liver function tests are altered due to hepatomegaly and cirrhosis of liver.[12]
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Gaucher Disease
Liver Biopsy Abnormal
Laboratory studies that show anemia and other hematological abnormalities, together with marked hepatosplenomegaly will usually indicate a bone marrow biopsy, which will show … Symptoms appear in adulthood and include enlarged liver and spleen, anemia, low thrombocyte count and skeletal abnormalities; Type 2 is the most severe form that develops … Cirrhosis of the liver is rare.[13]
[14]
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Phosphorylase Kinase Deficiency
Liver Biopsy Abnormal
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Acute Liver Failure
Liver Biopsy Abnormal
Liver Biopsy
A liver biopsy done via the transjugular route because of coagulopathy is not usually necessary, other than in occasional malignancies. … Multiple electrolyte abnormalities are common in ALF. … There is also abnormal oxygen transport and utilization.[15]
[16]