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975 Possible Causes for Liver Biopsy Normal

  • Gilbert Syndrome

    Other LFTs (including lactate dehydrogenase) and liver biopsy are normal; however, the latter should rarely be required.[] It shows a mildly raised level of bilirubin; however, all the other liver tests will be normal.[] Investigations FBC shows normal reticulocyte count - to distinguish from haemolysis.[]

  • Hypoglycemia

    Diagnosis by liver biopsy or genetics.[] Other signs/symptoms: high triglycerides/cholesterol, lactate, uric acid; LFTs usually normal or slightly elevated; bleeding such as recurrent epistaxis; neutropenia with[]

  • Arthritis

    Rarely, a liver biopsy is needed if liver function test findings are persistently twice the upper limit of normal or more and the patient needs to continue to use methotrexate[]

  • Polycystic Ovary Syndrome

    A repeat liver biopsy done 13 months after the initial biopsy revealed a substantial decrease in steatosis and a reduction in inflammation.[] […] physician and an exercise physiologist, the patient initiated a diet and exercise program that resulted in an 11.5% weight loss during approximately 8 months and yielded normalization[]

  • Hypercholesterolemia

    A liver biopsy obtained 5 months posttransplant showed chronic rejection versus ischemia, however, this improved with antiviral therapy, and the remainder of his liver biopsies[] Cholesterol levels quickly normalized after liver transplant. The lipid panel remained normal 1 year posttransplant, and the xanthomas regressed ( Fig 2 ).[] Aspirin therapy was continued, however statin therapy was not reinitiated post–liver transplant given the markedly normal lipids and risk of elevated liver function enzymes[]

  • Indian Childhood Cirrhosis

    Review of serial liver biopsy specimens showed a sequence of recovery from ICC through inactive micronodular cirrhosis to virtually normal histological appearances.[] No portal hypertension. • Ophthalmological examination NormalLiver biopsy micronodular cirrhosis with mallory hyaline disease and copper stain positive suggestive of Indian[] Hepatosplenomegaly reduced significantly and liver function tests returned to normal in all.[]

  • Acanthosis Nigricans

    Plasma glucose level, thyroid function test, liver and renal function tests were within normal limits. Ultrasonography of the abdomen was normal.[] Skin biopsy showed papillomatosis with minimal acanthosis. The stratum corneum was thickened and orthokeratotic.[]

  • Acidosis

    Other biochemical parameters, including tests of liver transaminases and bilirubin, were normal.[] A complete blood count revealed low counts in all three major cell lines and a subsequent bone marrow biopsy demonstrated B-cell follicular lymphoma.[]

  • Proteus

    Other serological examinations for autoantibodies, infection, liver and kidney function were normal.[] Thyroid hormones were within normal range and thyroid associated antibodies were negative.[] The renal biopsy revealed mild mesangial proliferative lesion and thickness of Bowman’s capsule without thickening of the glomerular basement membrane or spike.[]

  • Calcium Pyrophosphate Arthropathy

    A liver biopsy confirmed haemochromatosis. Regular phlebotomy was instituted. Eight months later his serum ferritin and liver function tests had returned to normal.[] The γ-glutamyltransferase was 65 (10–50 U/l) and the alanine aminotransferase 65 (5–40 U/l), the remainder of the liver function tests were normal.[]

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